KEGG   Chlorocebus sabaeus (green monkey): 103216291
Entry
103216291         CDS       T04361                                 
Symbol
PLCE1
Name
(RefSeq) phospholipase C epsilon 1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
csab  Chlorocebus sabaeus (green monkey)
Pathway
csab00562  Inositol phosphate metabolism
csab01100  Metabolic pathways
csab04014  Ras signaling pathway
csab04015  Rap1 signaling pathway
csab04020  Calcium signaling pathway
csab04024  cAMP signaling pathway
csab04070  Phosphatidylinositol signaling system
csab04919  Thyroid hormone signaling pathway
csab04933  AGE-RAGE signaling pathway in diabetic complications
csab05205  Proteoglycans in cancer
Module
csab_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:csab00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    103216291 (PLCE1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    103216291 (PLCE1)
   04015 Rap1 signaling pathway
    103216291 (PLCE1)
   04020 Calcium signaling pathway
    103216291 (PLCE1)
   04070 Phosphatidylinositol signaling system
    103216291 (PLCE1)
   04024 cAMP signaling pathway
    103216291 (PLCE1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    103216291 (PLCE1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103216291 (PLCE1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    103216291 (PLCE1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:csab04131]
    103216291 (PLCE1)
Enzymes [BR:csab01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     103216291 (PLCE1)
Membrane trafficking [BR:csab04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    103216291 (PLCE1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    103216291 (PLCE1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF RA C2 EF-hand_like GDPD
Other DBs
NCBI-GeneID: 103216291
NCBI-ProteinID: XP_007961794
Ensembl: ENSCSAG00000006211
UniProt: A0A0D9R1M1
Position
9:87214166..87559010
AA seq 2317 aa
MTSEEITASVLIPVTQRKVVSAQSAADESSEKVSDINISKAHTVRQSGETSHTISRLNKL
KEEPSGSNLPKILSITREKIVSDENSNEKCWEKSMPDSVKNLNINCNNILRNHQHGLPQR
QFYEMYNSVVEEDLCLETGILSPLERKVFPGIQLELDRPSMGINPLGNQSAIIETGRADP
DSSTAVFHFHYEVDRRMSDTFCTLSENLILDDCGNCVPLPGGEEKQKENYVAYTCKLMEL
AKNCDNKNEQLQCDHCDTLNDKYFCFEGSCQKVDMVYSSHSFCREDFTDSQTAKTFLSHF
EDFPDNCEDVEEDAFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLIA
WSYIDQKRNGPLLPCGRVMEPLSTVEIKQGGSRRLSEAQWYPIYNAVRRGEETENTVGSL
LHFFTKLPVSETAHGRISVGPCLKQCVRDTVYEYRATLQRTSISQYITGSLLEATTSLGA
RSGLLSTFGGSTGRMMLKERQPGPSVANSNTLPSSSAGISKELIDLQPLIQFPEEVASIL
MEQEQSIYRRVLPVDYLCFLTRDLGTPECQRSLPCLKASISASILTTQNGEHNALEDLVM
RFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKM
WQFMDQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDG
ASGLMKICPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCSR
SLETDEEDSPSEGNSSRKSSLKDKSRWQFIIGDLLDSDNDIFEQSKEYDSHGSEDSQQAF
DHGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWVKPTTA
SPANTKAKLGVLNNTAEPGKFPLLGNAGLSGLTEGVLDLFAVKAVYMGHPGIDIHTVCVQ
NKLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQR
QQWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSARNPSPGTSAKNAEKPSMQRNNTL
GISTTKKKKKILMRGESGEATDDEMATRKAKMHKECRSRSGSDPQDINEQEESEANTIAS
PPNPLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLPSSNKSPSSAWSSSSWHGRIKGG
MKGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCSRSGSESAPLYTNLM
IDENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSL
GIFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPNISMCHQGLMSFEGFARFLMDKEN
FASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELD
CWDGDDGMPIIYHGHTLTTKIPFKEVVEAINRSAFINSDLPIIISIENHCSLPQQRKMAE
IFKTVFGEKLVAKFLFETDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQL
ASMQAQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDADVLTASPAPNGQEDNILEDR
PENKSCNDKLQFEYSEEIPKRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPEL
SDLVIYCQAVKFPGLSTLNSSGSNRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSC
EGIRQTWEESSSPLNPTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLL
RTYPAATRIDSSNPNPIMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVL
WDKNCPMYQKFSPLERDLDSMDPVVYSLTIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCH
FRTKPIHRNTLNPMWNEQFLFRVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRH
LQLRNLHNEVLEISSLFINSRRMEENSSGSTMSASLMFNTEERKCLQTHRVTVHGVPGPE
PFTVFTINGGTKAKQLLQQILTTEQDIKPVTTDYFLMEEKYFISKEKNECRKQPFQRVIG
PEEEIVQILSSWFPEEGYVGRIVLKTQQENLEEKNIVQDDKEVILSSEEESFFVQVHDVS
PEQPRTVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKSTTP
KSSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQ
PRGLTSPSQLLTSESIQTKEEKPVGGLSSSDTMDYRQ
NT seq 6954 nt   +upstreamnt  +downstreamnt
atgacttctgaagaaattacagcttctgttctcatacctgtgactcagagaaaagtggtt
tctgcccagtcagctgcagatgaaagtagtgaaaaggtctcagacatcaatatttcaaaa
gcacatactgtcagacaaagtggggagacttctcataccatctcacgactgaacaaactt
aaagaagaaccttctggaagcaacttgccaaagattctctcaataacaagggagaaaata
gtgagtgatgagaacagtaatgaaaaatgctgggagaaaagcatgccagattctgtgaaa
aaccttaacattaactgcaacaacatattgagaaaccatcagcatggccttcctcaaaga
cagttttatgaaatgtacaactctgttgttgaggaagacctgtgtttagaaactggaatt
ctgtctccactggaaagaaaggtgttccctggaattcaactggaactagacagaccttcc
atgggcattaatcctttaggaaatcagtcggcaatcatagagacaggcagagcagaccct
gacagcagcacagcagtatttcattttcattatgaagttgacagaagaatgtcagacact
ttctgtaccctatcagaaaacttaattttagacgattgtggaaattgtgtaccactacct
gggggtgaggagaagcaaaaggaaaactatgtggcatatacctgtaaactgatggaattg
gccaaaaattgtgataataagaatgaacagctgcagtgtgatcattgtgacaccttgaat
gataaatacttttgctttgaaggctcttgccagaaggtggacatggtatattcaagtcat
agcttttgtagggaagattttactgacagtcaaactgccaagacctttttgagccatttt
gaggacttccctgataattgtgaagatgtagaagaagatgcttttaaaagcaaaaaggag
cggtccactttgttagtcaggagattctgtaaaaatgacagagaagttaagaaatctgtg
tataccggaacaagagcaattgtgaggactctgccttctggccacattgggctgattgca
tggagttacatagatcaaaagagaaatggtcccttactgccttgtgggagagtaatggaa
cccctatcaacagtggagataaagcaaggtgggagccgacgtctgtcagaagcccagtgg
tatcctatctacaatgcagtgagaagaggagaagaaacagaaaatacagttggatctcta
ctccatttcttcaccaagctcccagtctccgagacagcccatggaagaataagtgttggt
ccatgcttaaagcaatgtgtccgagacactgtatatgagtatcgcgccaccctccaaagg
acttcaatatcgcagtacatcaccggttctctcctagaagcaaccacgtctttgggagca
agaagtggccttctcagtacttttggaggatccactggacgaatgatgctgaaagaacgc
cagccaggcccctctgtggccaattccaacaccctcccttcaagttcagctggtatcagc
aaggagctgattgatctgcagcctctcatccagttcccagaggaagtcgccagcatcctg
atggagcaggagcagagtatttaccgcagggtcttgccggtcgactacctttgcttctta
acacgggacttgggcactcccgaatgccagaggtccctgccctgcctcaaagcatccatc
tcagcgtcgattcttaccactcagaatggagagcacaatgcccttgaagatctggtgatg
cggtttaatgaggtgagctcctgggtgacatggctgatcctcacggcaggctccatggag
gagaagcgagaagtcttttcatatttggtgcatgtggccaaatgctgctggaacatgggc
aattacaacgctgtcatggagttcttggctggcctcaggtcaagaaaagttttaaaaatg
tggcagtttatggaccagtctgatattgagaccatgaggagcctgaaggatgctatggcc
cagcatgagtcctcttgtgagtacagaaaggtggtgacacgtgccctgcacatccctggc
tgtaaggtggttccgttctgtggagtgtttctgaaggagctctgtgaagtgcttgacggc
gcctctggcctcatgaagatatgcccgcggtacaattcccaagaagaaactttagagttt
gtagcagattacagtggacaagataatttcttacaacgagtgggacaaaatggcttaaag
aattcggagaaggagtccactgtcaacagcatctttcaggtcatccggagctgcagtcga
agtctggagacagacgaggaggacagccccagtgaagggaacagctccaggaaaagttcc
ttgaaggataaaagccgatggcagtttataattggagatttgttggattcagacaatgat
atctttgagcaatccaaagaatatgactctcatggttcagaggactcacagcaggccttc
gaccatggaacggagctcatcccatggtatgtgctgtccatccaagccgatgtgcaccag
ttcctgctgcagggtgccacggtcatccactacgaccaggacacacacctctctgcccgc
tgcttcctccagcttcaacctgacaatagcaccttgacctgggtaaagcccacaactgcc
tccccagccaacactaaagcaaaacttggtgtacttaataacacagctgagcctggaaaa
ttcccactactgggcaatgctggattaagtggcctgacggaaggggtcttggatcttttt
gcagtgaaggcggtatacatgggccaccctggcattgatatacacactgtgtgtgttcag
aacaaattgggtagcatgttcctgtcagagactggtgtgacactgctctatgggcttcag
accacggacaatagattattgcacttcgtggcaccaaagcacacagctaaaatgctcttc
agcggattgttggaactcactagagctgtgagaaagatgaggaaattccctgaccaaaga
cagcagtggctgcggaaacagtacgtcagcctctatcaggaggatggacggtatgaaggc
ccaactttggctcatgctgtggagttgtttggtggcagacgatggagtgctcgaaacccc
agccccggcacatctgcaaagaatgctgagaagcccagtatgcagagaaacaacaccctg
ggcataagcactaccaagaaaaagaagaaaatcctcatgaggggtgagagtggagaggca
actgacgatgagatggcaacccgaaaggccaagatgcacaaagagtgtcgaagccggagt
ggttctgatcctcaagacattaatgaacaagaagaatcagaggcgaataccatcgctagc
ccgccaaaccccctcccttccagaagagcccactctttgaccacagctgggtcccccaac
ttggctgctgggacgtcatctcccatcaggccagtgtcctcccctgtgctgccttcttca
aacaagagcccgtccagtgcttggagcagtagtagctggcacgggcggatcaaaggtggc
atgaagggatttcagagcttcatggtttcagacagcaacatgagttttgttgaatttgtt
gagctgttcaaatcattcagtgtcaggagccgcaaggacctgaaggatctgtttgatgtc
tatgcagtgccctgcagccgatctggatccgagtcagccccgctctacaccaacttgatg
attgatgaaaacaccagcgatcttcagcctgacctagatctgttgaccagaaatgtctca
gatttggggttgttcatcaagagtaaacagcagctatcggacaaccagaggcagatatct
gatgccattgctgctgcaagcatcgtgacaaatggcactgggattgagagcacatctctg
ggcattttcggggtgggcatacttcagctcaacgatttcctcgtgaattgccaaggagaa
cactgcacttatgatgaaatcctcagcatcatccagaagtttgagcctaacatcagtatg
tgtcatcagggactaatgtcatttgaagggtttgcaaggtttctgatggataaagaaaat
tttgcctcaaaaaacgatgagtcacaggagaacattaaagaactgcagctacccctctca
tactattacatcgaatcttcgcacaatacctacctcacgggccatcagctcaaaggagaa
tcctcggtagaactctacagccaggtcctcttgcaaggctgtcgaagtgtagaattggac
tgctgggacggagacgatgggatgcccatcatttatcatggacatacactgacaaccaag
atccccttcaaggaagtggttgaagccattaatcgcagtgccttcatcaactctgacctg
ccaatcatcatatcgattgagaaccactgttcattgcctcagcaacgaaaaatggcagaa
attttcaagactgtgtttggagaaaagctggtggctaaattcttatttgagactgatttc
tcagatgatccaatgcttccttcacctgaccaactcagaaggaaagtgcttcttaaaaac
aagaaactaaaagcccatcagacaccagtggatatcttaaagcaaaaggctcatcagtta
gcatctatgcaagcgcaggcttataatggtgggaatgccaaccccccacctgccaataat
gaggaagaggaagatgaggaagacgaatatgattatgactatgaatccctttctgatgca
gatgtccttactgcctcccctgctcctaacggtcaggaagacaacattctggaagacaga
cctgaaaataaatcatgtaatgacaagcttcagtttgagtacagtgaagaaatccccaag
aggataaagaaggcagataactctgcttgcaacaaaggaaaggtttatgatatggaactg
ggagaagaattttatcttgatcagaataaaaaggaaagcagacagattgcaccagagctt
tctgaccttgtaatctattgtcaagcagtaaaatttccaggactgtcaactctaaattca
tctggctctaacagaggaaaggaaaggaaaagcaggaagtccatttttggcaacaatccg
ggcagaatgagcccaggggagacagcatcatttaacaaaacatctggaaaaagttcctgt
gaaggcattcgacagacctgggaggaatcttcttcccctctcaacccaaccacgtccctc
agtgctatcattagaactcccaaatgttatcatatctcgtcgctgaatgaaaatgcggcc
aaacgtctgtgtcgcaggtattctcagaaactgatccagcataccgcctgtcagctgctg
agaacttaccctgctgccacccgcatcgactcctccaacccgaaccccatcatgttctgg
cttcatgggatacagctcgtggcactcaactaccagaccgatgatctccctttacattta
aatgctgcaatgtttgaggcaaatggtggttgtggttatgttttgaaacctccagttctg
tgggacaagaactgcccgatgtatcagaagttttctccactggaaagagatctggacagc
atggatcctgtagtctattctttaactattgtctctggtcagaatgtgtgccccagtaac
agcacgggaagcccgtgcattgaagtcgatgtcctgggcatgcctctggacagctgccat
ttccgcacaaagcccatccatcgaaacaccctgaaccccatgtggaacgagcagtttctg
ttccgcgttcacttcgaagatcttgtatttcttcgttttgcagttgtggaaaacaacagt
tcagcggtaactgctcagagaatcattccactgaaagctttaaaacgaggatatcgacat
cttcagctgcgaaaccttcacaatgaagtcttggaaatctctagtttattcattaacagc
agaaggatggaagaaaattcctctggcagtaccatgtcagcctctttgatgtttaataca
gaagaaagaaaatgtttgcagactcacagagtcacggtgcatggggtcccagggccagag
ccctttactgttttcactattaatggaggcaccaaggcaaagcagcttctgcagcaaatt
ctgacaactgaacaagacatcaaacctgttaccacagactattttttgatggaagaaaaa
tattttatatctaaagaaaagaatgaatgcaggaaacaaccattccaaagagtcattgga
ccagaagaggagattgtgcaaattttaagcagctggtttccagaagagggatatgtgggc
aggattgtcttaaaaacccagcaggaaaacctagaagagaaaaacattgttcaagacgac
aaagaggtgatcttgagctcagaggaggagagtttctttgtccaagtgcatgatgtttct
ccagagcaacctcgaacagtcatcaaagcaccccgcgtcagcaccgcacaggatgtcatt
cagcagaccttatgcaaagccaaatattcctacagcatcctgagcaaccccaatccgagt
gactatgtgcttctggaagaggtggtgaaagacactaccaacaagaagtctaccacaccc
aagtcctctcagcgggtccttctggatcaggagtgtgtgtttcaagcccaaagcaagtgg
aaaggtgcaggaaaattcatccttaagctaaaggagcaggtgcaggcatctcgagaagat
aaaaagaaaggcatttcttttgcaagtgaactcaagaagctcaccaagtcaactaaacag
ccccgaggacttacatcaccttctcagctcttgacctcagaaagtatccaaaccaaggag
gagaaacctgtgggtggcttgtcctccagtgacacaatggattaccgacagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (10)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (8)   
   UniProt (1)   
   RefSeq(pep) (7)   
DNA sequence (7)   
   RefSeq(nuc) (7)   
Protein domain (7)   
   Pfam (7)   
All databases (54)   

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