KEGG   Chlorocebus sabaeus (green monkey): 103221339
Entry
103221339         CDS       T04361                                 
Symbol
GCLC
Name
(RefSeq) glutamate-cysteine ligase catalytic subunit
  KO
K11204  glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
Organism
csab  Chlorocebus sabaeus (green monkey)
Pathway
csab00270  Cysteine and methionine metabolism
csab00480  Glutathione metabolism
csab01100  Metabolic pathways
csab01240  Biosynthesis of cofactors
csab04216  Ferroptosis
Module
csab_M00118  Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:csab00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    103221339 (GCLC)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    103221339 (GCLC)
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    103221339 (GCLC)
Enzymes [BR:csab01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.2  glutamate---cysteine ligase
     103221339 (GCLC)
SSDB
Motif
Pfam: GCS GCS2
Other DBs
NCBI-GeneID: 103221339
NCBI-ProteinID: XP_007970416
Ensembl: ENSCSAG00000013162
UniProt: A0A0D9RL47
Position
17:19012994..19060617
AA seq 638 aa
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVRLVLSGEKVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EANMRKRRKEATSVLEENQALCTITSFPRLGCPGFTLPEVKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEASRASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKAAQKRDAVL
QGMFYFRKDICKAGGNAVVDGCGKAQNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILN
SYLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNY
SLILKCNQIANELCECPELLGSAFRKVKYGGSKTDSSN
NT seq 1917 nt   +upstreamnt  +downstreamnt
atggggctgctgtcccagggctcgccgctgagctgggaggaaaccaagcgccatgccgac
cacgtgcggcggcacgggatcctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgttctcaagtggggcgatgaggtggaatacatgttggtatcttttgatcat
gaaaataaaaaagtccgattggtcctgtctggggagaaagttcttgaaactctacaagag
aaaggggaaaggacaaacccaaaccatcctaccctttggagaccagagtatgggagttac
atgattgaagggacaccaggacagccctacggaggaacgatgtccgagttcaacacagtt
gaggccaacatgcgaaaacgccggaaggaggccacttctgtattagaagaaaatcaggct
ctttgcaccataacttcatttcccagattaggctgtcctgggttcacactgcccgaggtc
aaacccaacccagtggaaggaggagcttccaagtccctcttctttccagatgaagcaata
aacaagcaccctcgcttcagtaccttaacaagaaatatccgacataggagaggagaaaag
gttgtcatcaatgtaccaatatttaaggacaagaatacaccatctccatttatagaaaca
tttcctgaggatgatgaagcttcaagggcttctaagccagatcatatttacatggatgcc
atgggatttggaatgggcaattgctgtcttcaggtgacattccaagcctgcagtatatct
gaggccagatacctttatgatcagttggctactatctgtccaattgtcatggctttgagt
gctgcatctcccttttaccgaggctatgtgtcagacatcgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccattgaagaacaat
aactataggatcagtaaatcccgatatgactcaatagacagctatttatctaagtgtggt
gagaaatataatgacatcgacttgacaatagataaagagatctacgaacagctgttgcag
gaaggcattgatcatctcctggcccagcatgttgctcatctctttattagagacccactg
acactttttgaagagaaaatacacctggatgatgctaatgagtctgaccattttgagaat
attcagtccacaaattggcagacaatgagatttaagccccctcctccaaactcagacatc
ggatggagagtagaatttcgacccatggaggtgcaattaacagactttgagaactctgcc
tatgtggtgttcgtagtactgctcaccagagtgatcctttcgtacaaattggattttctc
attccactgtcaaaggttgatgagaacatgaaggcagcacagaaacgagatgctgtcttg
cagggaatgttttatttcaggaaagatatttgcaaagcaggtggcaacgcagtggtggat
ggttgtggcaaggcccagaacagcacagagcttgctgcagaggagtacaccctcatgagc
atagacaccatcatcaatgggaaggaaggtgtgtttcctggactgatcccaattctgaac
tcttaccttgaaaacatggaagtagatgtggacactagatgtagtattctgaactaccta
aagctaattaagaagagagcatctggagaactaatgacagttgccaggtggatgagggag
tttatcgcaaaccatcctgactacaagcaagacagtgtcataactgatgaaatgaattat
agccttattttgaagtgtaaccaaattgcaaatgaattatgtgaatgcccagagttactt
ggatcagcatttaggaaagtaaaatatggtggaagtaaaactgactcatccaactag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (2)   
   Pfam (2)   
All databases (32)   

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