KEGG   Chlorocebus sabaeus (green monkey): 103243514
Entry
103243514         CDS       T04361                                 
Symbol
TOP2A
Name
(RefSeq) topoisomerase (DNA) II alpha
  KO
K03164  DNA topoisomerase II [EC:5.6.2.2]
Organism
csab  Chlorocebus sabaeus (green monkey)
Pathway
csab01524  Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:csab00001]
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    103243514 (TOP2A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:csab03032]
    103243514 (TOP2A)
   03036 Chromosome and associated proteins [BR:csab03036]
    103243514 (TOP2A)
Enzymes [BR:csab01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.2  DNA topoisomerase (ATP-hydrolysing)
     103243514 (TOP2A)
DNA replication proteins [BR:csab03032]
 Eukaryotic type
  DNA Topoisomerases
   103243514 (TOP2A)
Chromosome and associated proteins [BR:csab03036]
 Eukaryotic type
  Chromosome condensation proteins
   Other regulators of chromosome condensation
    103243514 (TOP2A)
  Centrosome formation proteins
   Centriole proteins
    103243514 (TOP2A)
SSDB
Motif
Pfam: DNA_topoisoIV TOPRIM_C DNA_gyraseB DTHCT HATPase_c Toprim
Other DBs
NCBI-GeneID: 103243514
NCBI-ProteinID: XP_008010980
Ensembl: ENSCSAG00000002790
UniProt: A0A0D9S316
Position
16:65761391..65792041
AA seq 1531 aa
MEVSPLQPVNENMQVNKIKKNEDAKKRPSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFSGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQPKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSADCTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKMLNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMSFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSVTDSGPTFNYLLDMPLWYLTKEK
KDELCRLRNEKEQELDTLKRKSPSDLWKEDLATFIEELEAVEAKEKQDEQVGPPGKGGKA
KGKKTQMAEVLPSPRGQRVIPRITIEMKAEAEKKNKKKIKNENTEGSPQEDGMELEGLKQ
RLEKKQKREPGTKTKKQTTLSFKPIKKGKKRNPWSDSESDRSSDESNFDVPPRETEPRRA
ATKTKFTVDLDSDEDFSDFDEKTDDEDFVPSDASPPKTKTSPKLTNKDLKPQKSAMSDIE
ADDAKDSVPLSSSPPAAHFPNETEITNPVPKKNVTVKKTAAKSQSSTSTTGAKKRAAPKG
TKKEPALNSGISQKPDPAKTKIRRKRKPSTSDDSDSNFEKIVSKAVTSKKSRGESDDFHM
DFDSAVAPRAKSVRAKKPIKYLEESDEDDLF
NT seq 4596 nt   +upstreamnt  +downstreamnt
atggaagtgtcaccattgcagcctgtaaatgaaaatatgcaagtcaacaaaataaagaaa
aatgaagatgctaagaaaagaccgtctattgaaagaatctatcaaaagaaaacacagttg
gaacatattttgctccggccagacacctacattggttctgtggaattagtaacccagcaa
atgtgggtttacgatgaagatgttggcattaactatagggaagtcacttttgttcctggt
ttgtacaaaatctttgatgagattctagttaatgctgcggacaacaaacaaagggaccca
aaaatgtcttgtattagagtcacaattgatccggaaaacaatttaattagtatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgaaaagatgtatgtcccagctctc
atatttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtgacaggt
ggtcgaaatggctatggagccaaattgtgtaacatattcagtaccaaatttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacatggatggataatatggggaga
gctggtgagatggaactcaagcccttcagtggagaagattatacatgtatcacctttcag
cctgatttgtctaagtttaaaatgcaaagcctggacaaagatattgttgcactaatggtc
agaagagcatatgatattgctggatccaccaaagatgtcaaagtctttcttaatggaaat
aaactgccagtaaaaggatttcgtagttatgtggacatgtatttgaaagacaagttggat
gaaactggtaacccattgaaagtaatacatgaacaagtgaaccacaggtgggaagtgtgt
ttaaccatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatatttgtaaatgccttaattgaaaacccaacctttgactctcagacaaaagaaaac
atgactttacaaccaaagagctttggatcaacatgccaattaagtgaaaaatttatcaaa
gctgcaattggctgtggtattgtagaaagcatactaaactgggtgaaatttaaggcccaa
gtccagttaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattcccaaa
cttgatgatgccaatgatgcagggggccgaaattccgctgattgtacacttatcctgact
gagggagactcagccaaaactttggctgtttcaggccttggtgtggttgggagagacaaa
tacggggttttccctctgagaggaaaaatgctcaatgttcgagaagcttctcataagcag
atcatggaaaatgctgagattaacaatatcatcaaaattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcactgaagactcttcgttatgggaagataatgattatgaca
gatcaggaccaagatggttcccacatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgcgacatcgtttcctggaggaatttatcactcccattgtgaaggta
tccaaaaacaagcaagaaatgtcattttatagccttcctgaatttgaagaatggaagagt
tctactccaaatcataaaaaatggaaagtcaaatattacaaaggtttgggtaccagcaca
tcaaaggaagctaaagaatattttgcagatatgaaaagacatcgtatccagttcaaatat
tctggtcctgaagatgatgctgctatcagcctggcctttagcaaaaaacagatagatgat
cgaaaggaatggttaactaatttcatggaggatagaagacaacgaaagttacttggactt
cctgaggattacttgtatggacaaactaccacatatctgacatataatgacttcatcaac
aaggaacttatcttgttctcaaattctgataacgagagatctatcccttctatggtggat
ggtttgaaaccaggtcagagaaaggttttgtttacttgcttcaaacggaatgacaagcga
gaggtaaaggttgcccagttagctggatcagtggctgaaatgtcttcttatcatcatggt
gagatgtcattaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctgaacctcttgcagcccattggtcagtttggtaccaggctacatggtggcaaggattcc
gctagtccacgatacatcttcacaatgctcagctctttggctcggttgttatttccacca
aaagatgatcacacattgaagtttttatatgacgacaaccagcgtgttgagcctgaatgg
tacattcctattattcccatggtgctgataaatggtgctgaaggaatcggtaccgggtgg
tcctgcaaaatccccaactttgatgtacgtgaagttgtaaataacatcaggcgtttgatg
gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtactattgaa
gaactggctccaaatcaatatgtgattagtggtgaagtagctattcttaattccacaacc
attgaaatctcagagcttcccatcagaacatggacccagacatacaaagaacaagttcta
gaacccatgttgaatggcactgagaagacacctcctctcataacagactatagggaatac
catacagataccactgtgaaatttgttgtgaagatgactgaagaaaaactggcagaggca
gagagagttggactacacaaagtcttcaaactccaaactagtctcacatgcaactctatg
gtgctttttgaccacgtaggctgtttaaagaaatatgacacggtgttggatattctaaga
gacttttttgaactcagacttaaatattatggattaagaaaagaatggctcctaggaatg
cttggtgctgaatctgctaaactgaataatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagcctaagaaagaattaattaaagttctgattcagagg
ggatatgattcggatcctgtgaaggcctggaaagaagcccagcaaaaggttccagatgaa
gaagaaaatgaagagagtgacaatgaaaaggaaactgaaaagagtgactctgtaacagat
tctggaccaaccttcaactatcttcttgatatgcccctttggtatttaaccaaggaaaag
aaagatgaactctgcagactaagaaatgaaaaagaacaagagctggacacattaaagaga
aagagtccatcagatttgtggaaagaagacttggctacatttattgaagaactggaggct
gttgaagccaaggaaaaacaagatgaacaagttggacctcctgggaaaggggggaaggcc
aaggggaaaaaaacacaaatggctgaagttttgccttctccacgtggtcaaagagtcatt
ccgcgaataaccatagaaatgaaagcagaggcagaaaagaaaaataaaaagaaaattaag
aatgaaaatactgaaggaagccctcaagaagatggtatggaactagaaggcctaaaacaa
agattagaaaagaaacagaaaagagaaccaggtacaaagacaaagaaacaaactacattg
tcatttaagccaatcaaaaaaggaaagaagagaaatccctggtctgattcagaatcagat
aggagcagtgacgaaagtaattttgatgtccctccacgagaaacagagccacgaagagca
gcaacaaaaaccaaattcacagtggatttggattcagatgaagatttctcagattttgat
gaaaaaactgatgatgaagattttgtcccatcagatgctagtccacctaagaccaaaact
tccccaaaacttactaacaaagatctgaaacctcagaaaagtgctatgtcagacattgaa
gctgatgatgctaaggacagtgtaccactgtcttcaagccctcctgctgcacatttccca
aatgaaactgaaattacaaacccagttcctaaaaagaatgtgacagtgaagaagacagca
gcaaaaagtcagtcttccacctccactaccggtgccaaaaaaagggctgcccctaaagga
actaaaaaggaaccagctttgaattctggtatctctcaaaagcctgatcctgccaaaacc
aagattcgccgcaaaaggaagccatccacttctgatgattctgactctaattttgagaaa
attgtttcgaaagcagtcacaagcaagaaatccaggggggagagtgatgacttccatatg
gactttgactcagctgtggctcctcgggcaaaatctgtgcgggcaaagaaacctataaag
tacctggaagagtcagatgaagatgatctgttttaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (21)   

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