| Entry |
|
|---|
| Name |
Misoprostol (JAN/USP/INN);
Cytotec (TN) |
|---|
| Product |
|
|---|
| Generic |
MISOPROSTOL (ANI Pharmaceuticals), MISOPROSTOL (American Health Packaging), MISOPROSTOL (Bryant Ranch Prepack), MISOPROSTOL (GenBioPro), MISOPROSTOL (GenBioPro), MISOPROSTOL (GenBioPro), MISOPROSTOL (Greenstone LLC), MISOPROSTOL (Lupin Pharmaceuticals), MISOPROSTOL (Marlex Pharmaceuticals), MISOPROSTOL (Micro Labs Limited), MISOPROSTOL (Novel Laboratories), MISOPROSTOL (NuCare Pharmaceuticals), MISOPROSTOL (NuCare Pharmaceuticals), MISOPROSTOL (PD-Rx Pharmaceuticals), MISOPROSTOL (PD-Rx Pharmaceuticals), MISOPROSTOL (PD-Rx Pharmaceuticals), MISOPROSTOL (PharmPak), MISOPROSTOL (Pharmacist Pharmaceutical), MISOPROSTOL (Proficient Rx LP) |
|---|
| Formula |
C22H38O5
|
|---|
| Exact mass |
382.2719
|
|---|
| Mol weight |
382.5341
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Hormonal agent
DG01961 Prostaglandin derivative
DG01611 Prostaglandin E1 derivative
Gastrointestinal agent
DG01975 Agents for peptic ulcer
|
|---|
| Remark |
| Therapeutic category: | 2329 |
| Product (mixture): | D11091<US> D12586<JP> |
|
|---|
| Efficacy |
Anti-ulcerative, Prostaglandin E receptor agonist |
|---|
| Disease |
|
|---|
| Comment |
Prostaglandin E1 analog
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04750 | Inflammatory mediator regulation of TRP channels |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07228 | Eicosanoid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A02 DRUGS FOR ACID RELATED DISORDERS
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
A02BB Prostaglandins
A02BB01 Misoprostol
D00419 Misoprostol (JAN/USP/INN) <JP/US>
G GENITO URINARY SYSTEM AND SEX HORMONES
G02 OTHER GYNECOLOGICALS
G02A UTEROTONICS
G02AD Prostaglandins
G02AD06 Misoprostol
D00419 Misoprostol (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Gastrointestinal Agents
Protectants
Misoprostol
D00419 Misoprostol (JAN/USP/INN)
Hormonal Agents, Stimulant/Replacement/Modifying (Prostaglandins)
Misoprostol
D00419 Misoprostol (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
23 Digestive organ agents
232 Peptic ulcer agents
2329 Others
D00419 Misoprostol (JAN/USP/INN)
Drug groups [BR:br08330]
Hormonal agent
DG01961 Prostaglandin derivative
DG01611 Prostaglandin E1 derivative
D00419 Misoprostol
Gastrointestinal agent
DG01975 Agents for peptic ulcer
D00419 Misoprostol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Prostaglandin
PTGER2
D00419 Misoprostol (JAN/USP/INN) <JP/US>
PTGER3
D00419 Misoprostol (JAN/USP/INN) <JP/US>
PTGER4
D00419 Misoprostol (JAN/USP/INN) <JP/US>
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 27
1 C1y C 20.0900 -21.8400
2 C1y C 20.0900 -23.2400
3 C5x C 18.7600 -21.4200
4 C1b C 21.3500 -20.7900
5 C1y C 18.7600 -23.7300
6 C2b C 21.3500 -24.2900
7 C1x C 17.9900 -22.6100
8 O5x O 18.3400 -20.1600
9 O1a O 18.3400 -24.9900
10 C2b C 22.5400 -23.5900
11 C1b C 23.7300 -24.2900
12 C1d C 24.9200 -23.5900
13 C1b C 26.0400 -24.2900
14 C1b C 27.3000 -23.5900
15 C1b C 28.4900 -24.2900
16 C1a C 29.6800 -23.5900
17 C1b C 22.5400 -21.4900
18 C1b C 23.7300 -20.7900
19 C1b C 24.9200 -21.4900
20 C1b C 26.0400 -20.7900
21 C1b C 27.2300 -21.4900
22 C7a C 28.4200 -20.7900
23 O7a O 29.6800 -21.4900
24 O1a O 25.8300 -22.6100
25 C1a C 23.9400 -22.6100
26 C1a C 30.8807 -20.7701
27 O6a O 28.4028 -19.3901
BOND 27
1 1 2 1
2 1 3 1
3 1 4 1 #Down
4 2 5 1
5 2 6 1 #Up
6 3 7 1
7 3 8 2
8 5 9 1 #Down
9 6 10 2
10 10 11 1
11 11 12 1
12 12 13 1
13 13 14 1
14 14 15 1
15 15 16 1
16 5 7 1
17 4 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 20 21 1
22 21 22 1
23 22 23 1
24 12 24 1
25 12 25 1
26 23 26 1
27 22 27 2
|
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