| Entry |
|
|---|
| Name |
Armodafinil (USAN/INN);
Nuvigil (TN) |
|---|
| Product |
|
|---|
| Generic |
ARMODAFINIL (Aurobindo Pharma Limited), ARMODAFINIL (Bryant Ranch Prepack), ARMODAFINIL (Bryant Ranch Prepack), ARMODAFINIL (Bryant Ranch Prepack), ARMODAFINIL (DirectRx), ARMODAFINIL (Direct_Rx), ARMODAFINIL (Mylan Pharmaceuticals), ARMODAFINIL (Natco Pharma USA LLC), ARMODAFINIL (Preferred Pharmaceuticals), ARMODAFINIL (Preferred Pharmaceuticals), ARMODAFINIL (Preferred Pharmaceuticals), ARMODAFINIL (Quality Care Products LLC), ARMODAFINIL (Sandoz), ARMODAFINIL (Teva Pharmaceuticals USA), ARMODAFINIL (direct rx) |
|---|
| Formula |
C15H15NO2S
|
|---|
| Exact mass |
273.0823
|
|---|
| Mol weight |
273.3501
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01971 Agents for narcolepsy
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG02925 CYP3A5 substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Stimulant (central) |
|---|
| Disease |
|
|---|
| Comment |
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Metabolism |
Enzyme: CYP3A4 [HSA: 1576], CYP3A5 [HSA: 1577]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
N06BA Centrally acting sympathomimetics
N06BA13 Armodafinil
D03215 Armodafinil (USAN/INN) <US>
USP drug classification [BR:br08302]
Sleep Disorder Agents
Wakefulness Promoting Agents
Armodafinil
D03215 Armodafinil (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01971 Agents for narcolepsy
D03215 Armodafinil
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D03215 Armodafinil
DG02925 CYP3A5 substrate
D03215 Armodafinil
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A3 (DAT1)
D03215 Armodafinil (USAN/INN) <US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D03215
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 19
1 C8x C 14.9817 -17.5728
2 C8x C 14.9817 -18.9709
3 C8x C 16.1954 -19.6699
4 C8x C 17.4021 -18.9709
5 C8y C 17.4021 -17.5728
6 C8x C 16.1954 -16.8736
7 C1c C 18.6134 -16.8746
8 C8y C 19.8238 -17.5747
9 C8x C 19.8172 -18.9707
10 C8x C 21.0276 -19.6708
11 C8x C 22.2391 -18.9725
12 C8x C 22.2401 -17.5745
13 C8x C 21.0296 -16.8745
14 S4a S 18.6042 -15.4754
15 C1b C 19.8113 -14.7679
16 C5a C 19.8019 -13.3689
17 O3c O 17.3684 -14.7731
18 O5a O 18.5631 -12.6648
19 N1a N 21.0008 -12.6658
BOND 20
1 4 5 1
2 5 6 2
3 8 9 2
4 9 10 1
5 10 11 2
6 11 12 1
7 12 13 2
8 13 8 1
9 6 1 1
10 7 14 1
11 5 7 1
12 7 8 1
13 1 2 2
14 2 3 1
15 14 15 1 #Down
16 15 16 1
17 3 4 2
18 14 17 2
19 16 18 2
20 16 19 1
|
|---|
