KEGG   DRUG: Fendiline
Entry
D07185                      Drug                                   
Name
Fendiline (INN)
Formula
C23H25N
Exact mass
315.1987
Mol weight
315.4513
Structure
Simcomp
Class
Cardiovascular agent
 DG01575  Calcium channel blocker
  DG01496  Calcium channel L type blocker
 DG01653  Antiarrhythmics
  DG01807  Phenylalkylamine derivative
Remark
ATC code: C08EA01
Chemical structure group: DG00332
Efficacy
Vasodilator, Calcium channel blocker
Target
CACNA1-L [HSA:775 776 778 779] [KO:K04850 K04851 K04853 K04857]
  Pathway
hsa04020  Calcium signaling pathway
hsa04260  Cardiac muscle contraction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C08 CALCIUM CHANNEL BLOCKERS
   C08E NON-SELECTIVE CALCIUM CHANNEL BLOCKERS
    C08EA Phenylalkylamine derivatives
     C08EA01 Fendiline
      D07185  Fendiline (INN)
Drug groups [BR:br08330]
 Cardiovascular agent
  DG01575  Calcium channel blocker
   DG01496  Calcium channel L type blocker
    DG00332  Fendiline
     D07185  Fendiline
  DG01653  Antiarrhythmics
   DG01807  Phenylalkylamine derivative
    DG00332  Fendiline
     D07185  Fendiline
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Calcium channels
    CACNA1-L
     D07185  Fendiline (INN)
Drug groups [BR:br08330]
 Cardiovascular agent
  DG01575  Calcium channel blocker
   DG01496  Calcium channel L type blocker
    DG00332  Fendiline
  DG01653  Antiarrhythmics
   DG01807  Phenylalkylamine derivative
    DG00332  Fendiline
Other DBs
CAS: 13042-18-7
PubChem: 51091523
LigandBox: D07185
NIKKAJI: J8.079I
KCF data

ATOM        24
            1   C8x C     9.6600  -11.7600
            2   C8x C     9.6600  -13.1600
            3   C8x C    10.8724  -13.8600
            4   C8x C    12.0849  -13.1600
            5   C8y C    12.0849  -11.7600
            6   C8x C    10.8724  -11.0600
            7   C1c C    13.3160  -11.0490
            8   C8y C    14.5212  -11.7447
            9   C8x C    14.5216  -13.1596
            10  C8x C    15.7342  -13.8593
            11  C8x C    16.9465  -13.1589
            12  C8x C    16.9460  -11.7439
            13  C8x C    15.7334  -11.0443
            14  C1b C    13.3157   -9.6601
            15  C1b C    14.5162   -8.9666
            16  N1b N    15.7062   -9.6535
            17  C1c C    16.8960   -8.9662
            18  C8y C    18.0863   -9.6532
            19  C1a C    16.8959   -7.5602
            20  C8x C    18.0866  -11.0597
            21  C8x C    19.2992  -11.7595
            22  C8x C    20.5115  -11.0592
            23  C8x C    20.5112   -9.6527
            24  C8x C    19.2986   -8.9530
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    8  13 1
            15    7  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   17  19 1
            21   18  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   18  24 1

» Japanese version   » Back

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Drug (2)   
   KEGG DGROUP (1)   
   LigandBox (1)   
Chemical substance (2)   
   PubChem (1)   
   NIKKAJI (1)   
Gene (8)   
   KEGG ORTHOLOGY (4)   
   KEGG GENES (4)   
All databases (15)   

Download RDF
DBGET integrated database retrieval system