| Entry |
|
|---|
| Name |
Cefuroxime (USAN/INN);
Cefuroxime (TN) |
|---|
| Formula |
C16H16N4O8S
|
|---|
| Exact mass |
424.0689
|
|---|
| Mol weight |
424.3852
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Product (DG00558): | D00914<JP/US> D00915<US> |
|
|---|
| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07012 | Cephalosporins - parenteral agents |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DC Second-generation cephalosporins
J01DC02 Cefuroxime
D00262 Cefuroxime (USAN/INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA27 Cefuroxime
D00262 Cefuroxime (USAN/INN)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00558 Cefuroxime
D00262 Cefuroxime
DG01775 Second-generation cephalosporin
DG00558 Cefuroxime
D00262 Cefuroxime
DG01804 Oxyimino beta-lactam
DG00558 Cefuroxime
D00262 Cefuroxime
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Second-generation cephalosporin
D00262 Cefuroxime (USAN/INN)
Prodrugs [br08324.html]
D00262
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01714 Cephalosporin skeleton group
DG01488 Cephem
DG00558 Cefuroxime
DG01775 Second-generation cephalosporin
DG00558 Cefuroxime
DG01804 Oxyimino beta-lactam
DG00558 Cefuroxime
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Second-generation cephalosporin
DG00558 Cefuroxime
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 29
1 C1y C 32.5439 -17.8678
2 N1y N 32.5439 -19.2637
3 C2y C 33.7531 -19.9616
4 C2y C 34.9620 -19.2637
5 C1x C 34.9620 -17.8678
6 S2x S 33.7531 -17.1697
7 C1y C 31.1478 -17.8678
8 C5x C 31.1478 -19.2637
9 N1b N 29.9390 -17.1697
10 C5a C 28.7299 -17.8678
11 O5a O 28.7299 -19.2637
12 O5x O 29.9390 -19.9616
13 C2c C 27.5208 -17.1697
14 C1b C 36.1894 -19.9728
15 C6a C 33.7531 -21.3574
16 O6a O 32.5271 -22.0653
17 O6a O 34.9450 -22.0458
18 C8y C 26.2925 -17.8794
19 O2x O 25.1407 -17.0683
20 C8x C 24.0088 -17.9134
21 C8x C 24.4626 -19.2510
22 C8x C 25.8750 -19.2329
23 N2b N 27.5207 -15.7524
24 O7a O 37.4156 -19.2654
25 C7a C 38.6006 -19.9502
26 N1a N 39.7939 -19.2616
27 O6a O 38.6002 -21.3533
28 O2a O 28.7331 -15.0524
29 C1a C 28.7333 -13.6504
BOND 31
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1
8 7 8 1
9 2 8 1
10 7 9 1 #Up
11 9 10 1
12 10 11 2
13 8 12 2
14 10 13 1
15 4 14 1
16 3 15 1
17 15 16 2
18 15 17 1
19 13 18 1
20 18 19 1
21 19 20 1
22 20 21 2
23 21 22 1
24 18 22 2
25 13 23 2
26 14 24 1
27 24 25 1
28 25 26 1
29 25 27 2
30 23 28 1
31 28 29 1
|
|---|
