KEGG   DRUG: Nitrofurantoin
Entry
D00439                      Drug                                   
Name
Nitrofurantoin (JAN/USP/INN);
Furadantin (TN);
Macrobid (TN)
  Abbr
NIT
Product
FURADANTIN (Casper Pharma LLC), MACROBID (Almatica Pharma LLC), MACRODANTIN (Almatica Pharma LLC), NITROFURANTION MACROCRYSTALS (Proficient Rx LP), NITROFURANTION MACROCRYSTALS (Proficient Rx LP), NITROFURANTION MACROCRYSTALS (REMEDYREPACK), NITROFURANTOIN MACROCRYSTALS (Alvogen), NITROFURANTOIN MACROCRYSTALS (Bryant Ranch Prepack), NITROFURANTOIN MACROCRYSTALS (DIRECT RX), NITROFURANTOIN MACROCRYSTALS (Major Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (Northwind Pharmaceuticals), NITROFURANTOIN MONO (PharmPak), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (A-S Medication Solutions), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (A-S Medication Solutions), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Alvogen), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Denton Pharma), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Major Pharmaceuticals), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (NuCare Pharmaceuticals), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Proficient Rx LP), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Quality Care Products LLC), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (REMEDYREPACK), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (RPK Pharmaceuticals)
  Generic
NITROFURANTION (A-S Medication Solutions), NITROFURANTION (BluePoint Labortories), NITROFURANTION (Bryant Ranch Prepack), NITROFURANTION (NuCare Pharmaceuticals), NITROFURANTION (Proficient Rx LP), NITROFURANTION (Quality Care Products), NITROFURANTION (REMEDYREPACK), NITROFURANTION (Sun Pharmaceutical Industries), NITROFURANTOIN (A-S Medication Solutions), NITROFURANTOIN (A-S Medication Solutions), NITROFURANTOIN (A-S Medication Solutions), NITROFURANTOIN (A-S Medication Solutions), NITROFURANTOIN (A-S Medication Solutions), NITROFURANTOIN (A-S Medication Solutions), NITROFURANTOIN (ANI Pharmaceuticals), NITROFURANTOIN (Actavis Pharma), NITROFURANTOIN (Alembic Pharmaceuticals Limited), NITROFURANTOIN (Alembic Pharmaceuticals), NITROFURANTOIN (American Health Packaging), NITROFURANTOIN (American Health Packaging), NITROFURANTOIN (Amneal Pharmaceuticals LLC), NITROFURANTOIN (Amneal Pharmaceuticals LLC), NITROFURANTOIN (Amneal Pharmaceuticals NY LLC), NITROFURANTOIN (Aurobindo Pharma Limited), NITROFURANTOIN (Aurobindo Pharma Limited), NITROFURANTOIN (AvPAK), NITROFURANTOIN (BluePoint Laboratories), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Directrx), NITROFURANTOIN (Lupin Pharmaceuticals), NITROFURANTOIN (MACROCRYSTALS) (Aurobindo Pharma Limited), NITROFURANTOIN (MACROCRYSTALS) (Aurobindo Pharma Limited), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Asclemed USA), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (BluePoint Laboratories), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Bryant Ranch Prepack), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Jubilant Cadista Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Lifestar Pharma LLC), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (NorthStar RxLLC), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Northstar RxLLC), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Northwind Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Northwind Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (NuCare Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (NuCare Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (PD-Rx Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (PD-Rx Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Pharmasource Meds), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Pharmasource Meds), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Preferred Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Preferred Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Proficient Rx LP), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Proficient Rx LP), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (QPharma), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (QPharma), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Quality Care Products), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (REMEDYREPACK), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (REMEDYREPACK), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (REMEDYREPACK), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Sandoz), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (St. Mary's Medical Park Pharmacy), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Teva Pharmaceuticals USA), NITROFURANTOIN (NorthStar Rx LLC), NITROFURANTOIN (Northwind Pharmaceuticals), NITROFURANTOIN (Nostrum Laboratories), NITROFURANTOIN (Novel Laboratories), NITROFURANTOIN (NuCare Pharmaceuticals), NITROFURANTOIN (NuCare Pharmaceuticals), NITROFURANTOIN (NuCare Pharmaceuticals), NITROFURANTOIN (NuCare Pharmaceuticals), NITROFURANTOIN (PD-Rx Pharmaceuticals), NITROFURANTOIN (PD-Rx Pharmaceuticals), NITROFURANTOIN (Preferred Pharmaceuticals), NITROFURANTOIN (Proficient Rx LP), NITROFURANTOIN (Proficient Rx LP), NITROFURANTOIN (Proficient Rx LP), NITROFURANTOIN (REMEDYREPACK), NITROFURANTOIN (RPK Pharmaceuticals), NITROFURANTOIN (RPK Pharmaceuticals), NITROFURANTOIN (RPK Pharmaceuticals), NITROFURANTOIN (Redpharm Drug), NITROFURANTOIN (Redpharm Drug), NITROFURANTOIN (Rising Pharma Holdings), NITROFURANTOIN (Rising Pharma Holdings), NITROFURANTOIN (ST. MARY'S MEDICAL PARK PHARMACY), NITROFURANTOIN (Trigen Laboratories), NITROFURANTOIN MACROCRYSTALS (Amneal Pharmaceuticals of New York LLC), NITROFURANTOIN MACROCRYSTALS (AvPAK), NITROFURANTOIN MACROCRYSTALS (BluePoint Laboratories), NITROFURANTOIN MACROCRYSTALS (Bryant Ranch Prepack), NITROFURANTOIN MACROCRYSTALS (Bryant Ranch Prepack), NITROFURANTOIN MACROCRYSTALS (Direct_Rx), NITROFURANTOIN MACROCRYSTALS (Lifestar Pharma LLC), NITROFURANTOIN MACROCRYSTALS (Lupin Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (Major Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (NorthStar RxLLC), NITROFURANTOIN MACROCRYSTALS (Northwind Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (Novel Laboratories), NITROFURANTOIN MACROCRYSTALS (NuCare Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (NuCare Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (PD-Rx Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (PD-Rx Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (Proficient Rx LP), NITROFURANTOIN MACROCRYSTALS (REMEDYREPACK), NITROFURANTOIN MACROCRYSTALS (REMEDYREPACK), NITROFURANTOIN MACROCRYSTALS (Zydus Lifesciences Limited), NITROFURANTOIN MACROCRYSTALS (Zydus Pharmaceuticals (USA)), NITROFURANTOIN MONOHYDRATE/MACROCRYSTAL (Direct_Rx)
Formula
C8H6N4O5
Exact mass
238.0338
Mol weight
238.157
Structure
Simcomp
Class
Antibacterial
 DG01553  5-Nitrofuran antibacterial
  DG01552  Hydantoin type nitrofuran
Remark
Same as: C07268
ATC code: J01XE01
Product: D00439<US>
Efficacy
Antibacterial
  Disease
Uncomplicated urinary tract infection [DS:H01176]
Interaction
Other map
map04976  Bile secretion
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01X OTHER ANTIBACTERIALS
    J01XE Nitrofuran derivatives
     J01XE01 Nitrofurantoin
      D00439  Nitrofurantoin (JAN/USP/INN) <US>
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Nitrofurantoin
    D00439  Nitrofurantoin (JAN/USP/INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01553  5-Nitrofuran antibacterial
   DG01552  Hydantoin type nitrofuran
    D00439  Nitrofurantoin
Antimicrobials [BR:br08307]
 Antibacterials
  Bactericidal action
   Hydantoin type nitrofuran
    D00439  Nitrofurantoin (JAN/USP/INN) <US>
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Bactericidal action
   Hydantoin type nitrofuran
    D00439  Nitrofurantoin (JAN/USP/INN)
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and mutations affecting drug response
  D00439
Other DBs
CAS: 67-20-9
PubChem: 7847505
ChEBI: 71415
PDB-CCD: U6Z[PDBj]
LigandBox: D00439
NIKKAJI: J1.410I
KCF data

ATOM        17
            1   N1x N    23.7300  -16.2400
            2   C5x C    23.3100  -14.9800
            3   C1x C    21.9800  -14.9800
            4   N1y N    21.5600  -16.2400
            5   C5x C    22.6100  -17.0800
            6   O5x O    22.6100  -18.4800
            7   O5x O    24.0800  -13.8600
            8   N2b N    20.3700  -16.9400
            9   C2b C    19.1800  -16.2400
            10  C8y C    17.9900  -16.9400
            11  O2x O    16.8700  -16.1000
            12  C8y C    15.7500  -16.9400
            13  C8x C    16.1700  -18.2700
            14  C8x C    17.5700  -18.2700
            15  N2b N    14.6300  -16.2400 #+
            16  O3a O    13.1600  -17.2200 #-
            17  O3a O    14.6300  -14.9100
BOND        18
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     5   6 2
            7     2   7 2
            8     8   9 2
            9     8   4 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 2
            14   13  14 1
            15   10  14 2
            16   12  15 1
            17   15  16 1
            18   15  17 2

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Ontology (6)   
   KEGG BRITE (6)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (3)   
   KEGG DGROUP (1)   
   LigandBox (1)   
   SIDER (1)   
Chemical substance (6)   
   KEGG COMPOUND (1)   
   PubChem (1)   
   ChEBI (1)   
   HSDB (1)   
   NIKKAJI (1)   
   PDB-CCD (1)   
All databases (17)   

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