Entry |
|
Name |
Mefruside (JP18/USAN/INN); Baycaron (TN) |
Formula |
C13H19ClN2O5S2
|
Exact mass |
382.0424
|
Mol weight |
382.8834
|
Structure |
|
Class |
Cardiovascular agent
DG03231 Antihypertensive
DG02992 Thiazide related diuretic
DG01690 Sulfonamide diuretic
DG02992 Thiazide related diuretic
|
Remark |
Therapeutic category: | 2135 |
|
Efficacy |
Antihypertensive, Diuretic, Na+-Cl- symport inhibitor |
Comment |
Chlorbenzene sulfonamide derivative
|
Target |
|
Interaction |
|
Structure map |
map07017 | Sulfonamide derivatives - diuretics |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C03 DIURETICS
C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES
C03BA Sulfonamides, plain
C03BA05 Mefruside
D01877 Mefruside (JP18/USAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
213 Diuretics
2135 Chlorbenzene sulfonamides
D01877 Mefruside (JP18/USAN/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG02992 Thiazide related diuretic
D01877 Mefruside
DG01690 Sulfonamide diuretic
DG02992 Thiazide related diuretic
D01877 Mefruside
Drug classes [BR:br08332]
Cardiovascular agent
DG02992 Thiazide related diuretic
D01877 Mefruside
DG03231 Antihypertensive
D01877 Mefruside
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A3 (TSC)
D01877 Mefruside (JP18/USAN/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01877 Mefruside
D01877 Mefruside tablets
|
Other DBs |
|
KCF data |
ATOM 23
1 C8y C 19.7400 -16.0300
2 S4a S 18.5500 -15.3300
3 N1c N 17.3600 -16.0300
4 O3c O 19.7400 -14.6300
5 O3c O 17.3600 -14.6300
6 C1b C 16.1700 -15.3300
7 C1a C 17.3600 -17.4300
8 C1z C 14.9100 -16.0300
9 C1x C 13.6500 -15.4700
10 C1x C 12.7400 -16.4500
11 C1x C 13.4400 -17.7100
12 O2x O 14.9100 -17.4300
13 C1a C 14.9100 -14.6300
14 C8x C 20.9300 -15.3300
15 C8x C 19.7400 -17.4300
16 C8y C 22.1200 -16.0300
17 C8x C 20.9300 -18.1300
18 C8y C 22.1200 -17.4300
19 S4a S 23.3100 -15.4000
20 X Cl 23.3100 -18.1300
21 O3c O 22.5400 -14.2800
22 O3c O 24.2200 -16.6600
23 N1a N 24.5700 -14.7000
BOND 24
1 11 12 1
2 12 8 1
3 1 2 1
4 8 13 1
5 3 7 1
6 2 4 2
7 6 8 1
8 2 5 2
9 2 3 1
10 3 6 1
11 8 9 1
12 9 10 1
13 10 11 1
14 1 14 1
15 1 15 2
16 14 16 2
17 15 17 1
18 16 18 1
19 16 19 1
20 18 20 1
21 19 21 2
22 19 22 2
23 19 23 1
24 17 18 2
|