| Entry |
|
|---|
| Name |
Rolitetracycline (JAN/USAN/INN);
Synterin (TN) |
|---|
| Formula |
C27H33N3O8
|
|---|
| Exact mass |
527.2268
|
|---|
| Mol weight |
527.5662
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01197 Tetracycline antibiotic
|
|---|
| Remark |
|
|---|
| Efficacy |
Antibacterial, Protein biosynthesis inhibitor |
|---|
| Target |
30S ribosomal subunit |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01A TETRACYCLINES
J01AA Tetracyclines
J01AA09 Rolitetracycline
D02282 Rolitetracycline (JAN/USAN/INN)
Drug groups [BR:br08330]
Antibacterial
DG01197 Tetracycline antibiotic
DG00515 Rolitetracycline
D02282 Rolitetracycline
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Tetracycline
D02282 Rolitetracycline (JAN/USAN/INN)
Drug groups [BR:br08330]
Antibacterial
DG01197 Tetracycline antibiotic
DG00515 Rolitetracycline
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 38
1 C8x C 23.7013 -16.7748
2 C8x C 23.7013 -18.2161
3 C8y C 24.9101 -18.9135
4 C8x C 24.9101 -16.0774
5 C8y C 26.1190 -16.7748
6 C8y C 26.1190 -18.2161
7 C5x C 27.3278 -18.9135
8 C1z C 27.3278 -16.0774
9 C1y C 28.5367 -16.8213
10 C2y C 28.5367 -18.2161
11 C2y C 29.7456 -18.9135
12 C1x C 29.7920 -16.1239
13 C1y C 30.9544 -16.8213
14 C1z C 30.9544 -18.2161
15 C5x C 32.1633 -18.9135
16 C2y C 33.3721 -18.2626
17 C2y C 33.3721 -16.8678
18 C1y C 32.2097 -16.1239
19 C5a C 34.5810 -18.9601
20 N1b N 35.7899 -18.2626
21 C1b C 36.9987 -18.9601
22 N1y N 38.2075 -18.2626
23 C1x C 39.5505 -18.7120
24 C1x C 40.3926 -17.6157
25 C1x C 39.5937 -16.4224
26 C1x C 38.2306 -16.8621
27 N1c N 32.2097 -14.7290
28 C1a C 33.4186 -14.0782
29 C1a C 31.0009 -14.0316
30 C1a C 27.8858 -14.5889
31 O1a O 26.6305 -14.5889
32 O1a O 24.9101 -20.3084
33 O5x O 27.3278 -20.3084
34 O1a O 29.7456 -20.3084
35 O5x O 32.1633 -20.3549
36 O5a O 34.5810 -20.3549
37 O1a O 34.6275 -16.1704
38 O1a O 30.9544 -19.6109
BOND 42
1 5 4 2
2 21 22 1
3 4 1 1
4 9 10 1
5 10 11 2
6 22 23 1
7 23 24 1
8 24 25 1
9 25 26 1
10 26 22 1
11 11 14 1
12 18 27 1 #Down
13 13 12 1
14 27 28 1
15 12 9 1
16 27 29 1
17 1 2 2
18 2 3 1
19 8 30 1 #Down
20 5 6 1
21 8 31 1 #Up
22 6 7 1
23 3 32 1
24 7 10 1
25 7 33 2
26 13 14 1
27 11 34 1
28 14 15 1
29 15 35 2
30 15 16 1
31 19 36 2
32 16 17 2
33 17 37 1
34 17 18 1
35 14 38 1 #Down
36 18 13 1
37 9 8 1
38 16 19 1
39 8 5 1
40 19 20 1
41 3 6 2
42 20 21 1
|
|---|
