| Entry |
|
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| Name |
Tobramycin sulfate (USP);
Nebcin (TN) |
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| Product |
|
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| Generic |
TOBRAMYCIN (Baxter Healthcare Corporation), TOBRAMYCIN (Eugia US LLC), TOBRAMYCIN (Fosun Pharma USA), TOBRAMYCIN (Fresenius Kabi USA), TOBRAMYCIN (Fresenius Kabi USA), TOBRAMYCIN (Fresenius Kabi USA), TOBRAMYCIN (Gland Pharma Limited), TOBRAMYCIN (Gland Pharma Limited), TOBRAMYCIN (Gland Pharma Limited), TOBRAMYCIN (Hospira), TOBRAMYCIN (Mylan Institutional LLC), TOBRAMYCIN (XGen Pharmaceuticals DJB), TOBRAMYCIN (Xiromed LLC) |
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| Formula |
(C18H37N5O9)2. 5H2SO4
|
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| Exact mass |
1424.3552
|
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| Mol weight |
1425.4214
|
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| Structure |
|
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| Class |
Antibacterial
DG01447 Aminoglycoside antibiotic
|
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| Remark |
| Product (DG00608): | D00063<JP/US> D02542<US> |
|
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| Efficacy |
Antibacterial, Protein biosynthesis inhibitor |
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| Target |
50S ribosomal subunit
30S ribosomal subunit |
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| Pathway |
|
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01G AMINOGLYCOSIDE ANTIBACTERIALS
J01GB Other aminoglycosides
J01GB01 Tobramycin
D02542 Tobramycin sulfate (USP) <US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA12 Tobramycin
D02542 Tobramycin sulfate (USP) <US>
USP drug classification [BR:br08302]
Antibacterials
Aminoglycosides
Tobramycin
D02542 Tobramycin sulfate (USP)
Ophthalmic Agents
Ophthalmic Anti-Infectives
Antibacterials, Ophthalmic
Tobramycin
D02542 Tobramycin sulfate (USP)
Drug groups [BR:br08330]
Antibacterial
DG01447 Aminoglycoside antibiotic
DG00608 Tobramycin
D02542 Tobramycin sulfate
Drug classes [BR:br08332]
Antibacterial
DG01447 Aminoglycoside antibiotic
D02542 Tobramycin sulfate
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Aminoglycoside
D02542 Tobramycin sulfate (USP) <US>
Drug groups [BR:br08330]
Antibacterial
DG01447 Aminoglycoside antibiotic
DG00608 Tobramycin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Aminoglycoside
DG00608 Tobramycin
|
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| Other DBs |
|
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| KCF data |
ATOM 89
1 C1y C 16.6047 -20.3920
2 C1y C 16.6047 -21.7937
3 C1y C 17.7961 -22.4945
4 C1y C 19.0576 -21.7937
5 C1y C 19.0576 -20.3920
6 O2x O 17.7961 -19.6912
7 C1b C 15.4133 -19.6912
8 O1a O 14.2218 -20.3920
9 O1a O 15.4133 -22.4945
10 N1a N 17.7961 -23.8962
11 O1a O 20.2490 -22.4945
12 O2a O 20.2490 -19.6912
13 C1y C 21.4404 -18.9904
14 C1y C 22.7019 -19.6912
15 C1x C 23.8933 -18.9904
16 C1y C 23.8933 -17.5887
17 C1y C 22.6318 -16.8879
18 C1y C 21.4404 -17.5887
19 N1a N 22.7019 -21.0929
20 N1a N 25.0146 -16.8879
21 O1a O 20.2490 -16.8879
22 O2a O 22.6318 -15.4862
23 C1y C 23.8232 -14.7854
24 O2x O 25.0847 -15.4862
25 C1y C 26.2761 -14.7854
26 C1y C 26.2761 -13.3838
27 C1x C 25.0146 -12.6829
28 C1y C 23.8232 -13.3838
29 C1b C 27.5376 -15.4862
30 N1a N 27.5376 -16.8879
31 O1a O 27.4675 -12.6128
32 N1a N 22.6318 -12.6829
33 S4a S 33.9151 -18.7101
34 O1d O 33.9151 -20.1117
35 O1d O 33.9151 -17.3084
36 O1d O 35.3168 -18.7101
37 O1d O 32.5135 -18.7101
38 C1y C 16.6047 -20.3920
39 C1y C 16.6047 -21.7937
40 C1y C 17.7961 -22.4945
41 C1y C 19.0576 -21.7937
42 C1y C 19.0576 -20.3920
43 O2x O 17.7961 -19.6912
44 O2a O 20.2490 -19.6912
45 C1y C 21.4404 -18.9904
46 C1y C 22.7019 -19.6912
47 C1x C 23.8933 -18.9904
48 C1y C 23.8933 -17.5887
49 C1y C 22.6318 -16.8879
50 C1y C 21.4404 -17.5887
51 O1a O 20.2490 -16.8879
52 O2a O 22.6318 -15.4862
53 C1y C 23.8232 -14.7854
54 O2x O 25.0847 -15.4862
55 C1y C 26.2761 -14.7854
56 C1y C 26.2761 -13.3838
57 C1x C 25.0146 -12.6829
58 C1y C 23.8232 -13.3838
59 N1a N 22.6318 -12.6829
60 O1a O 27.4675 -12.6128
61 C1b C 27.5376 -15.4862
62 N1a N 27.5376 -16.8879
63 N1a N 25.0146 -16.8879
64 N1a N 22.7019 -21.0929
65 O1a O 20.2490 -22.4945
66 N1a N 17.7961 -23.8962
67 O1a O 15.4133 -22.4945
68 C1b C 15.4133 -19.6912
69 O1a O 14.2218 -20.3920
70 S4a S 33.9151 -18.7101
71 O1d O 33.9151 -20.1117
72 O1d O 33.9151 -17.3084
73 O1d O 35.3168 -18.7101
74 O1d O 32.5135 -18.7101
75 S4a S 33.9151 -18.7101
76 O1d O 33.9151 -20.1117
77 O1d O 33.9151 -17.3084
78 O1d O 35.3168 -18.7101
79 O1d O 32.5135 -18.7101
80 S4a S 33.9151 -18.7101
81 O1d O 33.9151 -20.1117
82 O1d O 33.9151 -17.3084
83 O1d O 35.3168 -18.7101
84 O1d O 32.5135 -18.7101
85 S4a S 33.9151 -18.7101
86 O1d O 33.9151 -20.1117
87 O1d O 33.9151 -17.3084
88 O1d O 35.3168 -18.7101
89 O1d O 32.5135 -18.7101
BOND 88
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 1 7 1 #Up
8 7 8 1
9 2 9 1 #Down
10 3 10 1 #Up
11 4 11 1 #Down
12 5 12 1 #Down
13 13 12 1 #Down
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 17 18 1
19 13 18 1
20 14 19 1 #Up
21 16 20 1 #Up
22 18 21 1 #Up
23 17 22 1 #Down
24 23 22 1 #Down
25 23 24 1
26 24 25 1
27 25 26 1
28 26 27 1
29 27 28 1
30 23 28 1
31 25 29 1 #Up
32 29 30 1
33 26 31 1 #Down
34 28 32 1 #Down
35 38 39 1
36 39 40 1
37 40 41 1
38 41 42 1
39 42 43 1
40 38 43 1
41 38 68 1 #Up
42 68 69 1
43 39 67 1 #Down
44 40 66 1 #Up
45 41 65 1 #Down
46 42 44 1 #Down
47 45 44 1 #Down
48 45 46 1
49 46 47 1
50 47 48 1
51 48 49 1
52 49 50 1
53 45 50 1
54 46 64 1 #Up
55 48 63 1 #Up
56 50 51 1 #Up
57 49 52 1 #Down
58 53 52 1 #Down
59 53 54 1
60 54 55 1
61 55 56 1
62 56 57 1
63 57 58 1
64 53 58 1
65 55 61 1 #Up
66 61 62 1
67 56 60 1 #Down
68 58 59 1 #Down
69 33 34 2
70 33 35 2
71 33 36 1
72 33 37 1
73 70 71 2
74 70 72 2
75 70 73 1
76 70 74 1
77 75 76 2
78 75 77 2
79 75 78 1
80 75 79 1
81 80 81 2
82 80 82 2
83 80 83 1
84 80 84 1
85 85 86 2
86 85 87 2
87 85 88 1
88 85 89 1
BRACKET 1 12.8100 -24.7100 12.8100 -11.2000
1 29.4000 -11.2000 29.4000 -24.7100
1 2
ORIGINAL 1 1 2 3 4 5 6 12 13 14 15 16 17 18 21 22 23
1 24 25 26 27 28 32 31 29 30 20 19 11 10 9 7 8
REPEAT 1 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53
1 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69
2 31.2200 -20.6500 31.2200 -16.5900
2 36.7500 -16.5900 36.7500 -20.6500
2 5
ORIGINAL 2 33 34 35 36 37
REPEAT 2 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85
2 86 87 88 89
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