| Entry |
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| Name |
Rifamycin (USAN/INN);
Rifamycin SV |
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| Formula |
C37H47NO12
|
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| Exact mass |
697.3098
|
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| Mol weight |
697.7686
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| Structure |
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| Simcomp |
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| Sequence |
0 Ahb 1 Mtn 2 Man 3 Mtd 4 Mtk 5 Mtk 6 Mtk 7 Mtk 8 Mtd
9 Mad 10 Mtn |
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| Type |
PK |
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| Source |
Amycolatopsis mediterranei [TAX: 33910]
|
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| Class |
|
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| Remark |
| Product (DG00640): | D08480<US> |
|
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| Efficacy |
Antibacterial (tuberculostatic) |
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| Comment |
Rifamycin derivative
|
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| Interaction |
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| Biosynthesis |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07A INTESTINAL ANTIINFECTIVES
A07AA Antibiotics
A07AA13 Rifamycin
D02549 Rifamycin (USAN/INN)
D DERMATOLOGICALS
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE
D06AX Other antibiotics for topical use
D06AX15 Rifamycin
D02549 Rifamycin (USAN/INN)
J ANTIINFECTIVES FOR SYSTEMIC USE
J04 ANTIMYCOBACTERIALS
J04A DRUGS FOR TREATMENT OF TUBERCULOSIS
J04AB Antibiotics
J04AB03 Rifamycin
D02549 Rifamycin (USAN/INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA16 Rifamycin
D02549 Rifamycin (USAN/INN)
S02 OTOLOGICALS
S02A ANTIINFECTIVES
S02AA Antiinfectives
S02AA12 Rifamycin
D02549 Rifamycin (USAN/INN)
Drug groups [BR:br08330]
Antibacterial
DG01966 Antitubercular
DG01598 Rifamycin antibiotic
DG00640 Rifamycin
D02549 Rifamycin
Antimicrobials [BR:br08307]
Antibacterials
Nucleic acid synthesis inhibitor
Rifamycin
D02549 Rifamycin (USAN/INN)
Drug groups [BR:br08330]
Antibacterial
DG01966 Antitubercular
DG01598 Rifamycin antibiotic
DG00640 Rifamycin
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| Other DBs |
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| KCF data |
ATOM 50
1 C1c C 22.2618 -13.6612
2 C1c C 22.2618 -15.0783
3 O1a O 24.6237 -15.0109
4 C1c C 24.6237 -13.6612
5 C1c C 23.4090 -12.9864
6 C2b C 26.9181 -13.6612
7 C1c C 25.7709 -12.9864
8 C5a C 28.1327 -15.7532
9 C2c C 29.2800 -15.0783
10 C2b C 29.2800 -13.6612
11 C2b C 28.1327 -12.9864
12 C1a C 25.7709 -11.6367
13 C1a C 23.4090 -11.6367
14 O1a O 21.1146 -12.9864
15 C1a C 30.4272 -15.7532
16 O5a O 26.9855 -15.0783
17 N1b N 28.1327 -17.3728
18 C1c C 21.1146 -15.7532
19 O7a O 19.9674 -15.0783
20 C1c C 21.1146 -17.3728
21 C8y C 26.9855 -18.0476
22 C8x C 26.9855 -19.3973
23 C8y C 25.7709 -17.3728
24 C8y C 24.6237 -18.0476
25 C8y C 24.6237 -19.3973
26 C8y C 25.7709 -20.0721
27 C8y C 23.4764 -17.3728
28 C8y C 22.2618 -18.0476
29 C8y C 22.2618 -19.3973
30 C8y C 23.4764 -20.0721
31 O1a O 25.7709 -16.0231
32 O1a O 23.4764 -16.0231
33 C1a C 21.1146 -13.9987
34 C7a C 18.7526 -14.4035
35 C1a C 17.6054 -15.0783
36 O6a O 18.7526 -13.0538
37 C1c C 19.9674 -18.0476
38 O2a O 18.8201 -17.3728
39 C2b C 19.9674 -19.3973
40 C1a C 19.9674 -16.4280
41 C1a C 17.6729 -18.0476
42 C2b C 18.8201 -20.0721
43 O2a O 18.8201 -21.4218
44 O2x O 21.1146 -20.0721
45 C1z C 21.1146 -21.4218
46 C5x C 23.4764 -21.4218
47 C1a C 21.1146 -22.7714
48 C1a C 22.2618 -16.6979
49 O1a O 25.7709 -21.4218
50 O5x O 24.5562 -22.0966
BOND 53
1 1 2 1
2 4 3 1 #Down
3 4 5 1
4 1 5 1
5 6 7 1
6 4 7 1
7 8 9 1
8 9 10 2
9 10 11 1
10 6 11 2
11 7 12 1 #Up
12 5 13 1 #Down
13 1 14 1 #Down
14 9 15 1
15 8 16 2
16 8 17 1
17 2 18 1
18 18 19 1 #Up
19 18 20 1
20 17 21 1
21 21 22 1
22 21 23 2
23 23 24 1
24 24 25 1
25 25 26 1
26 24 27 2
27 27 28 1
28 28 29 2
29 29 30 1
30 25 30 2
31 23 31 1
32 27 32 1
33 2 33 1 #Up
34 19 34 1
35 34 35 1
36 34 36 2
37 26 22 2
38 20 37 1
39 37 38 1 #Down
40 37 39 1
41 20 40 1 #Down
42 38 41 1
43 39 42 2
44 42 43 1
45 29 44 1
46 44 45 1
47 43 45 1
48 30 46 1
49 45 46 1
50 45 47 1 #Down
51 28 48 1
52 26 49 1
53 50 46 2
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