| Entry |
|
|---|
| Name |
Floxacillin (USAN);
Flucloxacillin (INN);
Floxapen (TN) |
|---|
| Formula |
C19H17ClFN3O5S
|
|---|
| Exact mass |
453.0561
|
|---|
| Mol weight |
453.8718
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antibacterial
DG01710 beta-Lactam antibiotic
DG01713 Penicillin skeleton group
DG01480 Penicillin
DG01779 beta-Lactamase resistant penicillin
|
|---|
| Remark |
|
|---|
| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Target |
penicillin binding protein |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
J01CF Beta-lactamase resistant penicillins
J01CF05 Flucloxacillin
D04196 Floxacillin (USAN)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01713 Penicillin skeleton group
DG01480 Penicillin
DG00543 Flucloxacillin
D04196 Floxacillin
DG01779 beta-Lactamase resistant penicillin
DG00543 Flucloxacillin
D04196 Floxacillin
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
beta-Lactamase resistant penicillin
D04196 Floxacillin (USAN)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01713 Penicillin skeleton group
DG01480 Penicillin
DG00543 Flucloxacillin
DG01779 beta-Lactamase resistant penicillin
DG00543 Flucloxacillin
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
beta-Lactamase resistant penicillin
DG00543 Flucloxacillin
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 30
1 C1y C 31.7482 -14.5450
2 C5x C 31.7482 -15.9092
3 N1y N 33.1124 -15.9092
4 C1y C 33.1124 -14.5450
5 C1y C 34.4084 -16.3184
6 C1z C 35.2269 -15.2271
7 S2x S 34.4084 -14.1358
8 C1a C 36.1818 -16.1820
9 C1a C 36.1818 -14.2722
10 C6a C 34.8858 -17.6825
11 O6a O 36.2500 -17.6825
12 O6a O 34.0673 -18.7739
13 N1b N 30.5887 -13.8629
14 C5a C 29.4291 -14.5450
15 O5x O 30.5887 -16.5913
16 O5a O 29.4291 -15.9092
17 C8y C 28.2014 -13.8629
18 C8y C 28.2014 -12.4988
19 O2x O 26.9039 -12.0772
20 N5x N 26.1021 -13.1808
21 C8y C 26.9039 -14.2845
22 C8y C 26.9039 -16.8764
23 C8y C 25.7290 -17.5547
24 C8x C 25.7289 -18.9189
25 C8x C 26.9103 -19.6009
26 C8x C 28.0853 -18.9227
27 C8y C 28.0853 -17.5585
28 C1a C 29.3050 -11.6969
29 X Cl 24.5567 -16.8778
30 X F 29.2567 -16.8821
BOND 33
1 1 2 1
2 2 3 1
3 3 4 1
4 1 4 1
5 3 5 1
6 5 6 1
7 6 7 1
8 4 7 1
9 6 8 1
10 6 9 1
11 5 10 1 #Down
12 10 11 1
13 10 12 2
14 1 13 1 #Up
15 13 14 1
16 2 15 2
17 14 16 2
18 14 17 1
19 17 18 2
20 18 19 1
21 19 20 1
22 20 21 2
23 17 21 1
24 21 22 1
25 22 23 2
26 23 24 1
27 24 25 2
28 25 26 1
29 26 27 2
30 22 27 1
31 18 28 1
32 23 29 1
33 27 30 1
|
|---|
