KEGG   DRUG: Neomycin
Entry
D08260                      Drug                                   
Name
Neomycin (INN);
Fradiomycin;
Neomycin;
Kaomycine (TN)
Formula
C12H25N4O5R
Structure
Simcomp
Source
Streptomyces Fradiae [TAX:1906]
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Same as: C00384
ATC code: A01AB08 A07AA01 B05CA09 D06AX04 J01GB05 R02AB01 S01AA03 S02AA07 S03AA01
Chemical structure group: DG00003
Product (DG00003): D01618<JP/US>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Comment
R: See Neomycin [CPD:C00384]
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AB Antiinfectives and antiseptics for local oral treatment
     A01AB08 Neomycin
      D08260  Neomycin (INN)
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA01 Neomycin
      D08260  Neomycin (INN)
 B BLOOD AND BLOOD FORMING ORGANS
  B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
   B05C IRRIGATING SOLUTIONS
    B05CA Antiinfectives
     B05CA09 Neomycin
      D08260  Neomycin (INN)
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX04 Neomycin
      D08260  Neomycin (INN)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB05 Neomycin
      D08260  Neomycin (INN)
 R RESPIRATORY SYSTEM
  R02 THROAT PREPARATIONS
   R02A THROAT PREPARATIONS
    R02AB Antibiotics
     R02AB01 Neomycin
      D08260  Neomycin (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA03 Neomycin
      D08260  Neomycin (INN)
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA07 Neomycin
      D08260  Neomycin (INN)
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03A ANTIINFECTIVES
    S03AA Antiinfectives
     S03AA01 Neomycin
      D08260  Neomycin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00003  Neomycin
    D08260  Neomycin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D08260  Neomycin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00003  Neomycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00003  Neomycin
Other DBs
CAS: 1404-04-2
PubChem: 96024948
ChEBI: 7507
NIKKAJI: J872I
KCF data

ATOM        22
            1   R   R    20.5100  -18.6200
            2   O1a O    20.5800  -21.4200
            3   C1y C    21.8400  -20.7200
            4   C1y C    23.0300  -21.4200
            5   C1x C    24.2200  -20.7200
            6   C1y C    24.2200  -19.3200
            7   C1y C    23.0300  -18.6200
            8   C1y C    21.8400  -19.3200
            9   N1a N    23.0300  -22.8200
            10  N1a N    25.4100  -18.6200
            11  O2a O    23.0300  -17.2200
            12  C1y C    24.2200  -16.5200
            13  O2x O    25.4100  -17.2200
            14  C1y C    26.6000  -16.5200
            15  C1y C    26.6000  -15.1200
            16  C1y C    25.4100  -14.4200
            17  C1y C    24.2200  -15.1200
            18  C1b C    27.8600  -17.1500
            19  N1a N    27.8600  -18.5500
            20  N1a N    22.9600  -14.4200
            21  O1a O    25.4100  -13.0200
            22  O1a O    27.8600  -14.3500
BOND        23
            1    13  14 1
            2    14  15 1
            3    15  16 1
            4    16  17 1
            5    17  12 1
            6    14  18 1 #Up
            7     3   2 1 #Down
            8    18  19 1
            9    17  20 1 #Down
            10   16  21 1 #Up
            11   15  22 1 #Down
            12    3   4 1
            13    4   5 1
            14    5   6 1
            15    6   7 1
            16    7   8 1
            17    8   3 1
            18    4   9 1 #Up
            19    6  10 1 #Up
            20    7  11 1 #Down
            21    8   1 1 #Up
            22   12  11 1 #Down
            23   12  13 1

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Ontology (3)   
   KEGG BRITE (3)   
Drug (2)   
   KEGG DGROUP (1)   
   SIDER (1)   
Chemical substance (5)   
   KEGG COMPOUND (1)   
   PubChem (1)   
   ChEBI (1)   
   HSDB (1)   
   NIKKAJI (1)   
All databases (10)   

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