| Entry |
|
|---|
| Name |
Isoflurophate;
Fluostigmine;
Floropryl (TN) |
|---|
| Formula |
C6H14FO3P
|
|---|
| Exact mass |
184.0665
|
|---|
| Mol weight |
184.1457
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
DG01594 Butyrylcholinesterase inhibitor
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Acetylcholinesterase inhibitor, Butyrylcholinesterase inhibitor (ophthalmic) |
|---|
| Comment |
Reversible cholinesterase inhibitor
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EB Parasympathomimetics
S01EB07 Fluostigmine
D00043 Isoflurophate
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01595 Cholinesterase inhibitor
DG01593 Acetylcholinesterase inhibitor
D00043 Isoflurophate
DG01594 Butyrylcholinesterase inhibitor
D00043 Isoflurophate
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D00043 Isoflurophate
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Carboxylic-ester hydrolases
ACHE
D00043 Isoflurophate
BCHE
D00043 Isoflurophate
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 11
1 P1b P 23.2694 -15.1480
2 O2b O 21.8252 -15.1480
3 O2b O 23.2694 -16.5348
4 O3b O 23.2183 -13.7549
5 X F 24.6114 -15.1545
6 C1c C 20.3425 -15.1352
7 C1c C 23.2694 -17.9279
8 C1a C 19.6268 -14.0802
9 C1a C 19.6715 -16.3495
10 C1a C 22.0616 -18.6183
11 C1a C 24.4709 -18.6183
BOND 10
1 1 2 1
2 1 3 1
3 1 4 2
4 1 5 1
5 2 6 1
6 3 7 1
7 6 8 1
8 6 9 1
9 7 10 1
10 7 11 1
|
|---|
