KEGG DRUG: Dinoprost

DRUG: Dinoprost

Entry

D00081                      Drug

Name

Dinoprost (JP18/USAN/INN);
Prosmon (TN)

Formula

C20H34O5

Exact mass

354.2406

Mol weight

354.481

Structure

Simcomp

Class

Hormonal agent
DG01961 Prostaglandin derivative
DG01960 Prostaglandin F derivative

Remark

Same as:

C00639

Therapeutic category:

2499

ATC code:

G02AD01

Chemical structure group:

DG00447

Product (DG00447):

D00081<JP>

Efficacy

Oxytocic, Prostaglandin F receptor agonist

Comment

Prostaglandin derivative

Target

PTGFR [HSA:5737] [KO:K04262]

Pathway

hsa04020

Calcium signaling pathway

hsa04080

Neuroactive ligand-receptor interaction

Interaction

Structure map

map07035

Prostaglandins

map07228

Eicosanoid receptor agonists/antagonists

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
  G02 OTHER GYNECOLOGICALS
   G02A UTEROTONICS
    G02AD Prostaglandins
     G02AD01 Dinoprost
      D00081  Dinoprost (JP18/USAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2499  Others
     D00081  Dinoprost (JP18/USAN/INN)
Drug groups [BR:br08330]
Hormonal agent
  DG01961  Prostaglandin derivative
   DG01960  Prostaglandin F derivative
    DG00447  Dinoprost
     D00081  Dinoprost
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
  Rhodopsin family
   Prostaglandin
    PTGFR
     D00081  Dinoprost (JP18/USAN/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
  D00081  Dinoprost
Drug groups [BR:br08330]
Hormonal agent
  DG01961  Prostaglandin derivative
   DG01960  Prostaglandin F derivative
    DG00447  Dinoprost

Other DBs

CAS:

551-11-1

PubChem:

7847149

ChEBI:

15553

PDB-CCD:

UGU[PDBj]

LigandBox:

D00081

NIKKAJI:

J9.246K

KCF data

ATOM        25
            1   C1y C    26.2459  -14.3536
            2   C1y C    26.2400  -15.7232
            3   C1y C    24.9454  -13.9393
            4   C1b C    27.6327  -13.1279
            5   C1y C    24.9626  -16.1432
            6   C2b C    27.6270  -16.8801
            7   C1x C    24.1513  -15.0498
            8   O1a O    24.5023  -12.6101
            9   C2b C    28.8066  -13.8184
            10  O1a O    24.5311  -17.4840
            11  C2b C    28.8010  -16.2069
            12  C2b C    30.1531  -13.8184
            13  C1c C    29.9748  -16.8801
            14  C1b C    31.3213  -13.1279
            15  C1b C    31.1489  -16.2069
            16  O1a O    29.9748  -18.2382
            17  C1b C    32.4837  -13.8013
            18  C1b C    32.3227  -16.8801
            19  C1b C    33.6577  -13.1223
            20  C1b C    33.5138  -16.2069
            21  C6a C    34.8258  -13.7897
            22  C1b C    34.6704  -16.8801
            23  O6a O    36.0226  -13.0818
            24  O6a O    34.8373  -15.1706
            25  C1a C    35.8616  -16.2069
BOND        25
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     3   8 1 #Down
            8     4   9 1
            9     5  10 1 #Down
            10    6  11 2
            11    9  12 2
            12   11  13 1
            13   12  14 1
            14   13  15 1
            15   13  16 1 #Down
            16   14  17 1
            17   15  18 1
            18   17  19 1
            19   18  20 1
            20   19  21 1
            21   20  22 1
            22   21  23 1
            23   21  24 2
            24   22  25 1
            25    5   7 1

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