| Entry |
|
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| Name |
Oxytocin (JP18/USP/INN);
Oxytocin (TN);
Pitocin (TN);
Syntocinon (TN) |
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| Product |
|
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| Generic |
|
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| Formula |
C43H66N12O12S2
|
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| Exact mass |
1006.4365
|
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| Mol weight |
1007.1873
|
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| Structure |
|
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| Simcomp |
|
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| Sequence |
Cys Tyr Ile Gln Asn Cys Pro Leu Gly (Disulfide bridge: 1-6) |
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| Type |
Peptide |
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| Remark |
| Therapeutic category: | 2414 |
|
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| Efficacy |
Oxytocic, Oxytocin receptor agonist |
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| Comment |
Posterior pituitary hormone
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
H01B POSTERIOR PITUITARY LOBE HORMONES
H01BB Oxytocin and analogues
H01BB02 Oxytocin
D00089 Oxytocin (JP18/USP/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
241 Pituitary hormone preparations
2414 Posterior pituitary hormones
D00089 Oxytocin (JP18/USP/INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Oxytocin
OXTR
D00089 Oxytocin (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00089 Oxytocin
D00089 Oxytocin injection
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| Other DBs |
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| KCF data |
ATOM 69
1 C8x C 26.7400 -15.1900
2 C8y C 26.7400 -16.5900
3 C8x C 27.9300 -17.2900
4 C8x C 29.1900 -16.5900
5 C8y C 29.1900 -15.1900
6 C8x C 27.9300 -14.4900
7 O1a O 25.5500 -17.2900
8 C1b C 30.3800 -14.4900
9 C1y C 32.1300 -15.1900
10 C5x C 33.3200 -14.4900
11 N1x N 32.1300 -16.5900
12 N1x N 34.5100 -15.1900
13 O5x O 33.3200 -13.0900
14 C5x C 30.9400 -17.2900
15 C1y C 30.9400 -18.6900
16 O5x O 29.7500 -16.5900
17 N1a N 29.7500 -19.3900
18 C1x C 32.1300 -19.3900
19 S3x S 32.1300 -20.7900
20 S3x S 33.3200 -21.4900
21 C1x C 34.5100 -20.7900
22 C1y C 35.7000 -21.4900
23 N1x N 36.8900 -20.7900
24 C5a C 35.7000 -22.8900
25 O5a O 34.5100 -23.5900
26 N1y N 36.8900 -23.5900
27 C1y C 36.8900 -24.9900
28 C1x C 38.2200 -25.4100
29 C1x C 39.0600 -24.2900
30 C1x C 38.2200 -23.1700
31 C5a C 35.7700 -25.8300
32 N1b N 34.5100 -25.2700
33 O5a O 35.7700 -27.2300
34 C5a C 32.1300 -25.2700
35 C1c C 33.3200 -25.9700
36 C1b C 33.3200 -27.3700
37 C1c C 32.1300 -28.0700
38 C1a C 30.9400 -27.3700
39 C1a C 32.1300 -29.4700
40 N1b N 30.9400 -25.9700
41 O5a O 32.1300 -23.8700
42 C1b C 29.7500 -25.2700
43 C5a C 28.5600 -25.9700
44 N1a N 27.3700 -25.2700
45 O5a O 28.5600 -27.3700
46 C5x C 36.8900 -19.3900
47 O5x O 35.7000 -18.6900
48 C1y C 38.0800 -18.6900
49 N1x N 38.0800 -17.2900
50 C5x C 39.2700 -16.5900
51 O5x O 40.5300 -17.2900
52 C1y C 39.2700 -15.1900
53 N1x N 38.0800 -14.4900
54 C5x C 36.8900 -15.1900
55 C1y C 35.7000 -14.4900
56 O5x O 36.8900 -16.5900
57 C1c C 35.7000 -13.0900
58 C1b C 36.8900 -12.3900
59 C1a C 38.0800 -13.0900
60 C1a C 34.5100 -12.3900
61 C1b C 39.3400 -19.3900
62 C1b C 40.4600 -14.4900
63 C1b C 41.7200 -15.1900
64 C5a C 42.9100 -14.4200
65 N1a N 44.1000 -15.1200
66 O5a O 42.9100 -13.0200
67 C5a C 39.3400 -20.7900
68 N1a N 40.5300 -21.4900
69 O5a O 38.1500 -21.4900
BOND 71
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1
8 5 8 1
9 9 8 1 #Up
10 9 10 1
11 9 11 1
12 10 12 1
13 10 13 2
14 11 14 1
15 14 15 1
16 14 16 2
17 15 17 1 #Down
18 15 18 1
19 18 19 1
20 19 20 1
21 20 21 1
22 21 22 1
23 22 23 1
24 22 24 1 #Down
25 24 25 2
26 24 26 1
27 26 27 1
28 27 28 1 #Up
29 28 29 1
30 29 30 1
31 26 30 1
32 27 31 1
33 31 32 1
34 31 33 2
35 34 35 1
36 35 32 1
37 35 36 1 #Up
38 36 37 1
39 37 38 1
40 37 39 1
41 34 40 1
42 34 41 2
43 40 42 1
44 42 43 1
45 43 44 1
46 43 45 2
47 23 46 1
48 46 47 2
49 46 48 1
50 48 49 1
51 49 50 1
52 50 51 2
53 50 52 1
54 52 53 1
55 53 54 1
56 55 54 1 #Up
57 55 12 1
58 54 56 2
59 55 57 1
60 57 58 1
61 58 59 1
62 57 60 1 #Up
63 48 61 1 #Up
64 52 62 1 #Up
65 62 63 1
66 63 64 1
67 64 65 1
68 64 66 2
69 61 67 1
70 67 68 1
71 67 69 2
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