| Entry |
|
|---|
| Name |
Aspirin (JP18/USP);
Aspalon (JAN);
Acetylsalicylic acid;
Easprin (TN);
Durlaza (TN) |
|---|
| Formula |
C9H8O4
|
|---|
| Exact mass |
180.0423
|
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| Mol weight |
180.1574
|
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| Structure |
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| Simcomp |
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| Class |
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01909 Anti-inflammatory drug, salicylic acid derivatives
|
|---|
| Remark |
| Product (DG00015): | D00109<JP> |
| Product (mixture): | D03960<JP> D10513<JP> D10527<JP> D11176<US> D11615<US> D11804<JP> D11849<US> D11859<US> D11860<US> |
|
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| Efficacy |
Analgesic, Anti-inflammatory, Antipyretic, Antirheumatic, Antiplatelet, COX inhibitor |
|---|
| Disease |
Myocardial infarction [DS: H01730] Unstable angina pectoris [DS: H01632] Chronic stable angina [DS: H01632] |
|---|
| Comment |
Salicylic acid derivative
|
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| Target |
|
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| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AD Other agents for local oral treatment
A01AD05 Acetylsalicylic acid
D00109 Aspirin (JP18/USP) <JP>
B BLOOD AND BLOOD FORMING ORGANS
B01 ANTITHROMBOTIC AGENTS
B01A ANTITHROMBOTIC AGENTS
B01AC Platelet aggregation inhibitors excl. heparin
B01AC06 Acetylsalicylic acid
D00109 Aspirin (JP18/USP) <JP>
N NERVOUS SYSTEM
N02 ANALGESICS
N02B OTHER ANALGESICS AND ANTIPYRETICS
N02BA Salicylic acid and derivatives
N02BA01 Acetylsalicylic acid
D00109 Aspirin (JP18/USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
114 Antipyretics and analgesics, anti-inflammatory agents
1143 Salicylates
D00109 Aspirin (JP18/USP); Aspalon (JAN)
3 Agents affecting metabolism
33 Blood and body fluid agents
339 Miscellaneous
3399 Others
D00109 Aspirin (JP18/USP); Aspalon (JAN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for nervous and sensory systems
01 Cold remedy (oral use)
D00109 Aspirin (JP18/USP)
03 Antipyretic analgesic agents
D00109 Aspirin (JP18/USP)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Aspirin
D00109 Aspirin (JP18/USP)
Second-class OTC drugs
Inorganic and organic chemicals
Aspirin
D00109 Aspirin (JP18/USP)
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
DG00015 Acetylsalicylic acid
D00109 Aspirin
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01909 Anti-inflammatory drug, salicylic acid derivatives
DG00015 Acetylsalicylic acid
D00109 Aspirin
Drug classes [BR:br08332]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
D00109 Aspirin
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D00109 Aspirin (JP18/USP) <JP>
PTGS2 (COX2)
D00109 Aspirin (JP18/USP) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00109 Aspirin
D00109 Aspirin tablets
Rx-to-OTC switch list in the USA [br08315.html]
D00109
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
DG00015 Acetylsalicylic acid
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01909 Anti-inflammatory drug, salicylic acid derivatives
DG00015 Acetylsalicylic acid
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| Other DBs |
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| KCF data |
ATOM 13
1 C8y C 20.2981 -15.8105
2 C8y C 21.5226 -16.5029
3 C8x C 19.0928 -16.5029
4 C6a C 20.2981 -14.6227
5 C8x C 21.5226 -17.9133
6 O7a O 22.7278 -15.8040
7 C8x C 19.0928 -17.9133
8 O6a O 21.5033 -13.9240
9 O6a O 19.0863 -13.9304
10 C8x C 20.2981 -18.6250
11 C7a C 23.9396 -16.4964
12 C1a C 25.1450 -15.7977
13 O6a O 23.9396 -17.8942
BOND 13
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 1
7 4 8 1
8 4 9 2
9 5 10 1
10 6 11 1
11 11 12 1
12 11 13 2
13 7 10 2
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