| Entry |
|
|---|
| Name |
Atropine (USP);
Atropen (TN) |
|---|
| Formula |
C17H23NO3
|
|---|
| Exact mass |
289.1678
|
|---|
| Mol weight |
289.3694
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Source |
Atropa belladonna [TAX: 33113]
|
|---|
| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
|
|---|
| Remark |
| Product (DG00052): | D02069<JP/US> |
| Product (mixture): | D12759<US> |
|
|---|
| Efficacy |
Mydriatic, Muscarinic acetylcholine receptor antagonist |
|---|
| Comment |
Tropane derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07220 | Cholinergic and anticholinergic drugs |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
A03B BELLADONNA AND DERIVATIVES, PLAIN
A03BA Belladonna alkaloids, tertiary amines
A03BA01 Atropine
D00113 Atropine (USP)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01F MYDRIATICS AND CYCLOPLEGICS
S01FA Anticholinergics
S01FA01 Atropine
D00113 Atropine (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00052 Atropine
D00113 Atropine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D00113 Atropine (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG00052 Atropine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C1x C 18.2238 -19.1608
2 C1x C 18.5519 -17.9891
3 C1y C 19.3955 -18.8796
4 C1y C 19.7236 -17.7079
5 N1y N 18.4582 -16.3956
6 C1x C 21.2702 -18.8796
7 C1x C 20.9890 -17.7079
8 C1y C 22.3013 -19.4420
9 O7a O 23.3793 -20.3325
10 C7a C 24.5979 -20.3325
11 C1c C 25.2072 -19.2545
12 O6a O 25.2072 -21.4573
13 C8y C 26.4258 -19.2545
14 C1b C 24.5979 -18.2234
15 O1a O 25.2072 -17.1455
16 C8x C 27.1320 -20.4782
17 C8x C 28.5320 -20.4785
18 C8x C 29.2322 -19.2662
19 C8x C 28.5261 -18.0425
20 C8x C 27.1261 -18.0422
21 C1a C 17.7091 -15.2114
BOND 23
1 1 2 1
2 1 3 1
3 2 4 1
4 3 5 1
5 3 6 1
6 4 7 1
7 6 8 1
8 8 9 1 #Down
9 9 10 1
10 10 11 1
11 10 12 2
12 11 13 1
13 11 14 1
14 14 15 1
15 4 5 1
16 7 8 1
17 13 16 2
18 16 17 1
19 17 18 2
20 18 19 1
21 19 20 2
22 13 20 1
23 5 21 1
|
|---|
