| Entry |
|
|---|
| Name |
Mercaptopurine (USP);
Mercaptopurine hydrate (JP18);
Purinethol (TN);
Purixan (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C5H4N4S. H2O
|
|---|
| Exact mass |
170.0262
|
|---|
| Mol weight |
170.1923
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antineoplastic
DG02018 Antimetabolite
DG01958 Nucleic acid derivative, antineoplastic
|
|---|
| Remark |
| Therapeutic category: | 4221 |
| Product (DG00683): | D00161<JP/US> |
|
|---|
| Efficacy |
Antineoplastic, Antimetabolite |
|---|
| Disease |
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07041 | Antineoplastics - antimetabolic agents |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01B ANTIMETABOLITES
L01BB Purine analogues
L01BB02 Mercaptopurine
D00161 Mercaptopurine (USP) <JP/US>
USP drug classification [BR:br08302]
Antineoplastics
Antimetabolites
Mercaptopurine
D00161 Mercaptopurine (USP)
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
42 Antineoplastics
422 Antimetabolites
4221 Mercaptopurines
D00161 Mercaptopurine (USP); Mercaptopurine hydrate (JP18)
Drug groups [BR:br08330]
Antineoplastic
DG02018 Antimetabolite
DG01958 Nucleic acid derivative, antineoplastic
DG00683 Mercaptopurine
D00161 Mercaptopurine
Drug classes [BR:br08332]
Antineoplastic
DG02018 Antimetabolite
D00161 Mercaptopurine
Target-based classification of drugs [BR:br08310]
Enzymes
Transferases (EC2)
Pentosyltransferases
HPRT1
D00161 Mercaptopurine (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00161 Mercaptopurine hydrate
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D00161
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00161
Drug groups [BR:br08330]
Antineoplastic
DG02018 Antimetabolite
DG01958 Nucleic acid derivative, antineoplastic
DG00683 Mercaptopurine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 11
1 O0 O 27.8600 -17.0568
2 C8y C 22.6100 -16.9400
3 C8y C 22.6100 -18.3400
4 C8y C 23.8000 -16.2400
5 N4x N 23.8000 -19.0400
6 N5x N 24.9900 -16.9400
7 S0 S 23.8000 -14.8400
8 C8x C 24.9900 -18.3400
9 N4x N 21.2100 -16.4500
10 C8x C 20.4400 -17.6400
11 N5x N 21.2100 -18.7600
BOND 11
1 2 3 2
2 2 4 1
3 3 5 1
4 4 6 1
5 4 7 2
6 5 8 1
7 6 8 2
8 2 9 1
9 9 10 1
10 10 11 2
11 3 11 1
|
|---|
