| Entry |
|
|---|
| Name |
Acarbose (JAN/USAN/INN);
Precose (TN) |
|---|
| Product |
|
|---|
| Generic |
ACARBOSE (A-S Medication Solutions), ACARBOSE (Aphena Pharma Solutions - Tennessee), ACARBOSE (AvKARE), ACARBOSE (Bryant Ranch Prepack), ACARBOSE (Bryant Ranch Prepack), ACARBOSE (Bryant Ranch Prepack), ACARBOSE (Chartwell RX), ACARBOSE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), ACARBOSE (Hikma Pharmaceuticals USA), ACARBOSE (PD-Rx Pharmaceuticals), ACARBOSE (Proficient Rx LP), ACARBOSE (Strides Pharma Science Limited), ACARBOSE (Virtus Pharmaceuticals LLC) |
|---|
| Formula |
C25H43NO18
|
|---|
| Exact mass |
645.248
|
|---|
| Mol weight |
645.6048
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Source |
|
|---|
| Class |
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01663 alpha-Glucosidase inhibitor
|
|---|
| Remark |
| Therapeutic category: | 3969 |
|
|---|
| Efficacy |
Antidiabetic, alpha-Glucosidase inhibitor |
|---|
| Disease |
Type 2 diabetes mellitus [DS: H00409] |
|---|
| Target |
|
|---|
| Pathway |
| hsa04973 | Carbohydrate digestion and absorption |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A10 DRUGS USED IN DIABETES
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
A10BF Alpha glucosidase inhibitors
A10BF01 Acarbose
D00216 Acarbose (JAN/USAN/INN) <JP/US>
USP drug classification [BR:br08302]
Blood Glucose Regulators
Antidiabetic Agents
Glucose Control Agents, Other
Acarbose
D00216 Acarbose (JAN/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
396 Antidiabetic agents
3969 Others
D00216 Acarbose (JAN/USAN/INN)
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01663 alpha-Glucosidase inhibitor
D00216 Acarbose
Drug classes [BR:br08332]
Antidiabetic agent
DG01663 alpha-Glucosidase inhibitor
D00216 Acarbose
DG02044 Hypoglycemic agent
D00216 Acarbose
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Glycosidases
AMY
D00216 Acarbose (JAN/USAN/INN) <JP/US>
GAA
D00216 Acarbose (JAN/USAN/INN) <JP/US>
GANC
D00216 Acarbose (JAN/USAN/INN) <JP/US>
MGAM
D00216 Acarbose (JAN/USAN/INN) <JP/US>
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 44
1 C1y C 18.1630 -9.4066
2 C1y C 18.1630 -10.8090
3 C1y C 19.4251 -11.5102
4 C1y C 20.6172 -10.8090
5 C2x C 20.6172 -9.4066
6 C2y C 19.4251 -8.7054
7 C1b C 19.4251 -7.3031
8 O1a O 20.6172 -6.6019
9 O1a O 16.9709 -11.5102
10 O1a O 19.4251 -12.9126
11 O1a O 16.9709 -8.7054
12 N1b N 21.8793 -11.5102
13 C1y C 23.0713 -10.8090
14 C1y C 24.2634 -11.5102
15 C1y C 25.4554 -10.8090
16 C1y C 25.4554 -9.4066
17 O2x O 24.2634 -8.7054
18 C1y C 23.0713 -9.4066
19 O2a O 26.7175 -8.7054
20 O1a O 24.2634 -12.9126
21 O1a O 26.6474 -11.5102
22 C1a C 21.8092 -8.7054
23 C1y C 27.9096 -6.6019
24 C1y C 27.9096 -8.0043
25 C1y C 29.1016 -8.7054
26 C1y C 30.3638 -8.0043
27 C1y C 30.3638 -6.6019
28 O2x O 29.1016 -5.9007
29 C1b C 26.7175 -5.9007
30 O1a O 29.1016 -10.1078
31 O1a O 31.5558 -8.7054
32 O2a O 31.5558 -5.9007
33 O1a O 25.5255 -6.6019
34 C1y C 32.7478 -3.7971
35 C1y C 32.7478 -5.1995
36 C1y C 33.9399 -5.9007
37 C1y C 35.2020 -5.1995
38 C1y C 35.2020 -3.7971
39 O2x O 33.9399 -3.0959
40 C1b C 31.5558 -3.0959
41 O1a O 33.9399 -7.3031
42 O1a O 36.3940 -3.0959
43 O1a O 36.3940 -5.9007
44 O1a O 30.3638 -3.7971
BOND 47
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 2
6 1 6 1
7 6 7 1
8 7 8 1
9 2 9 1 #Up
10 3 10 1 #Down
11 1 11 1 #Down
12 4 12 1 #Down
13 13 12 1 #Down
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 17 18 1
19 13 18 1
20 16 19 1 #Down
21 14 20 1 #Up
22 15 21 1 #Down
23 18 22 1 #Up
24 23 24 1
25 24 25 1
26 25 26 1
27 26 27 1
28 27 28 1
29 23 28 1
30 23 29 1 #Up
31 25 30 1 #Up
32 24 19 1 #Down
33 26 31 1 #Down
34 27 32 1 #Down
35 29 33 1
36 34 35 1
37 35 36 1
38 36 37 1
39 37 38 1
40 38 39 1
41 34 39 1
42 34 40 1 #Up
43 36 41 1 #Up
44 38 42 1 #Either
45 37 43 1 #Down
46 35 32 1 #Down
47 40 44 1
|
|---|
