 | | DRUG: Acetazolamide | |
| Entry |
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| Name |
Acetazolamide (JP18/USP/INN);
Diamox (TN) |
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| Product |
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| Generic |
ACETAZOLAMIDE (A-S Medication Solutions), ACETAZOLAMIDE (A-S Medication Solutions), ACETAZOLAMIDE (A-S Medication Solutions), ACETAZOLAMIDE (A-S Medication Solutions), ACETAZOLAMIDE (A-S Medication Solutions), ACETAZOLAMIDE (ANI Pharmaceuticals), ACETAZOLAMIDE (Aarkish Pharmaceuticals NJ), ACETAZOLAMIDE (Accord Healthcare), ACETAZOLAMIDE (Advagen Pharma), ACETAZOLAMIDE (Ajanta Pharma USA), ACETAZOLAMIDE (Alembic Pharmaceuticals Limited), ACETAZOLAMIDE (Alembic Pharmaceuticals), ACETAZOLAMIDE (American Health Packaging), ACETAZOLAMIDE (American Health Packaging), ACETAZOLAMIDE (AvKARE), ACETAZOLAMIDE (AvPAK), ACETAZOLAMIDE (Bryant Ranch Prepack), ACETAZOLAMIDE (Bryant Ranch Prepack), ACETAZOLAMIDE (Bryant Ranch Prepack), ACETAZOLAMIDE (Bryant Ranch Prepack), ACETAZOLAMIDE (Bryant Ranch Prepack), ACETAZOLAMIDE (Bryant Ranch Prepack), ACETAZOLAMIDE (Chartwell RX), ACETAZOLAMIDE (Chartwell RX), ACETAZOLAMIDE (Eywa Pharma), ACETAZOLAMIDE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), ACETAZOLAMIDE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), ACETAZOLAMIDE (Ingenus Pharmaceuticals), ACETAZOLAMIDE (Lifestar Pharma LLC), ACETAZOLAMIDE (Major Pharmaceuticals), ACETAZOLAMIDE (Marlex Pharmaceuticals), ACETAZOLAMIDE (Northwind Pharmaceuticals), ACETAZOLAMIDE (Nostrum Laboratories), ACETAZOLAMIDE (NuCare Pharmaceuticals), ACETAZOLAMIDE (PD-Rx Pharmaceuticals), ACETAZOLAMIDE (PD-Rx Pharmaceuticals), ACETAZOLAMIDE (PD-Rx Pharmaceuticals), ACETAZOLAMIDE (Proficient Rx LP), ACETAZOLAMIDE (Strides Pharma Science Limited), ACETAZOLAMIDE (TRUPHARMA), ACETAZOLAMIDE (Taro Pharmaceuticals U.S.A.), ACETAZOLAMIDE (Viona Pharmaceuticals), ACETAZOLAMIDE (Westminster Pharmaceuticals), ACETAZOLAMIDE (Zydus Lifesciences Limited), ACETAZOLAMIDE (Zydus Lifesciences Limited), ACETAZOLAMIDE (Zydus Pharmaceuticals (USA)), ACETAZOLAMIDE (Zydus Pharmaceuticals (USA)), ACETAZOLAMIDE EXTENDED-RELEASE (AvPAK), ACETAZOLAMIDE EXTENDED-RELEASE (Micro Labs Limited) |
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| Formula |
C4H6N4O3S2
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| Exact mass |
221.9881
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| Mol weight |
222.2454
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| Structure |
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| Simcomp |
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| Class |
Cardiovascular agent
DG01534 Carbonic anhydrase inhibitor
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
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| Remark |
| Therapeutic category: | 2134 |
| Product (DG01134): | D00218<JP/US> D01196<JP/US> |
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| Efficacy |
Antiglaucoma, Carbonic anhydrase inhibitor |
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| Disease |
Chronic simple (open-angle) glaucoma [DS: H00612] |
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| Comment |
Sulfonamide derivative
Diuretic action
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| Target |
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| Pathway |
| hsa04964 | Proximal tubule bicarbonate reclamation |
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| Interaction |
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| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
| map07055 | Sulfonamide derivatives - overview |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EC Carbonic anhydrase inhibitors
S01EC01 Acetazolamide
D00218 Acetazolamide (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Cardiovascular Agents, Other
Acetazolamide
D00218 Acetazolamide (JP18/USP/INN)
Ophthalmic Agents
Intraocular Pressure Lowering Agents
Carbonic Anhydrase Inhibitors, Ophthalmic
Acetazolamide
D00218 Acetazolamide (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
213 Diuretics
2134 Carbonic anhydrase inhibitors
D00218 Acetazolamide (JP18/USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01534 Carbonic anhydrase inhibitor
DG01134 Acetazolamide
D00218 Acetazolamide
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01134 Acetazolamide
D00218 Acetazolamide
Drug classes [BR:br08332]
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D00218 Acetazolamide
Target-based classification of drugs [BR:br08310]
Enzymes
Lyases (EC4)
Aldehyde-lyases
CA
D00218 Acetazolamide (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00218 Acetazolamide
Drug groups [BR:br08330]
Cardiovascular agent
DG01534 Carbonic anhydrase inhibitor
DG01134 Acetazolamide
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01134 Acetazolamide
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| Other DBs |
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| KCF data |
ATOM 13
1 C8y C 19.6602 -17.3655
2 S2x S 20.7952 -16.5406
3 N5x N 20.0991 -18.6934
4 S4a S 18.2620 -17.3595
5 C8y C 21.9303 -17.3655
6 N5x N 21.4973 -18.6934
7 N1a N 18.2503 -18.7579
8 O3c O 18.2503 -15.9613
9 O3c O 16.8579 -17.3595
10 N1b N 23.1354 -16.6517
11 C5a C 24.3464 -17.3538
12 C1a C 25.5574 -16.6459
13 O5a O 24.3464 -18.7519
BOND 13
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 1
7 4 8 2
8 4 9 2
9 5 10 1
10 10 11 1
11 11 12 1
12 11 13 2
13 5 6 2
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