 | | DRUG: Allopurinol | |
| Entry |
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| Name |
Allopurinol (JP18/USP/INN);
Zyloprim (TN) |
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| Product |
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| Generic |
ALLOPURINOL (A-S Medication Solutions), ALLOPURINOL (A-S Medication Solutions), ALLOPURINOL (A-S Medication Solutions), ALLOPURINOL (A-S Medication Solutions), ALLOPURINOL (A-S Medication Solutions), ALLOPURINOL (A-S Medication Solutions), ALLOPURINOL (A-S Medication Solutions), ALLOPURINOL (A-S Medication Solutions), ALLOPURINOL (Accord Healthcare), ALLOPURINOL (Advanced Rx Pharmacy of Tennessee), ALLOPURINOL (American Health Packaging), ALLOPURINOL (Aphena Pharma Solutions - Tennessee), ALLOPURINOL (Aphena Pharma Solutions - Tennessee), ALLOPURINOL (Aphena Pharma Solutions - Tennessee), ALLOPURINOL (Aphena Pharma Solutions - Tennessee), ALLOPURINOL (Aphena Pharma Solutions - Tennessee), ALLOPURINOL (Aphena Pharma Solutions - Tennessee), ALLOPURINOL (Aphena Pharma Solutions - Tennessee), ALLOPURINOL (Aphena Pharma Solutions - Tennessee), ALLOPURINOL (Aphena Pharma Solutions - Tennessee), ALLOPURINOL (Aphena Pharma Solutions - Tennessee), ALLOPURINOL (Bryant Ranch Prepack), ALLOPURINOL (Bryant Ranch Prepack), ALLOPURINOL (Bryant Ranch Prepack), ALLOPURINOL (Bryant Ranch Prepack), ALLOPURINOL (Bryant Ranch Prepack), ALLOPURINOL (Bryant Ranch Prepack), ALLOPURINOL (Bryant Ranch Prepack), ALLOPURINOL (Bryant Ranch Prepack), ALLOPURINOL (Bryant Ranch Prepack), ALLOPURINOL (Bryant Ranch Prepack), ALLOPURINOL (Bryant Ranch Prepack), ALLOPURINOL (Bryant Ranch Prepack), ALLOPURINOL (Bryant Ranch Prepack), ALLOPURINOL (Camber Pharmaceuticals), ALLOPURINOL (Cardinal Health 107), ALLOPURINOL (Cardinal Health 107), ALLOPURINOL (Cardinal Health 107), ALLOPURINOL (Chartwell RX), ALLOPURINOL (DIRECT RX), ALLOPURINOL (Denton Pharma), ALLOPURINOL (Denton Pharma), ALLOPURINOL (Direct_Rx), ALLOPURINOL (Direct_Rx), ALLOPURINOL (Direct_Rx), ALLOPURINOL (Dr. Reddy's Laboratories Limited), ALLOPURINOL (Florida Pharmaceutical Products), ALLOPURINOL (Harman Finochem Limited), ALLOPURINOL (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), ALLOPURINOL (Leading Pharma), ALLOPURINOL (Major Pharmaceuticals), ALLOPURINOL (Major Pharmaceuticals), ALLOPURINOL (McKesson Corporation dba SKY Packaging), ALLOPURINOL (Mylan Institutional), ALLOPURINOL (Mylan Pharmaceuticals), ALLOPURINOL (NCS HealthCare of KY), ALLOPURINOL (NorthStar RxLLC), ALLOPURINOL (Northstar RxLLC), ALLOPURINOL (Northwind Pharmaceuticals), ALLOPURINOL (Northwind Pharmaceuticals), ALLOPURINOL (Northwind Pharmaceuticals), ALLOPURINOL (Northwind Pharmaceuticals), ALLOPURINOL (Northwind Pharmaceuticals), ALLOPURINOL (Northwind Pharmaceuticals), ALLOPURINOL (NuCare Pharmaceuticals), ALLOPURINOL (NuCare Pharmaceuticals), ALLOPURINOL (NuCare Pharmaceuticals), ALLOPURINOL (NuCare Pharmaceuticals), ALLOPURINOL (NuCare Pharmaceuticals), ALLOPURINOL (PD-Rx Pharmaceuticals), ALLOPURINOL (PD-Rx Pharmaceuticals), ALLOPURINOL (PD-Rx Pharmaceuticals), ALLOPURINOL (PD-Rx Pharmaceuticals), ALLOPURINOL (Par Pharmaceutical), ALLOPURINOL (Preferred Pharmaceuticals), ALLOPURINOL (Preferred Pharmaceuticals), ALLOPURINOL (Preferred Pharmaceuticals), ALLOPURINOL (Preferred Pharmaceuticals), ALLOPURINOL (Preferred Pharmaceuticals), ALLOPURINOL (Preferred Pharmaceuticals), ALLOPURINOL (Proficient Rx LP), ALLOPURINOL (Proficient Rx LP), ALLOPURINOL (Proficient Rx LP), ALLOPURINOL (Quality Care Products), ALLOPURINOL (Quality Care Products), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (RPK Pharmaceuticals), ALLOPURINOL (Redpharm Drug), ALLOPURINOL (Rising Pharma Holdings), ALLOPURINOL (ST. MARY'S MEDICAL PARK PHARMACY), ALLOPURINOL (ST. MARY'S MEDICAL PARK PHARMACY), ALLOPURINOL (St. Mary's Medical Park Pharmacy), ALLOPURINOL (St. Mary's Medical Park Pharmacy), ALLOPURINOL (Sun Pharmaceutical Industries), ALLOPURINOL (Unichem Pharmaceuticals (USA)), ALLOPURINOL (Zydus Lifesciences Limited), ALLOPURINOL (Zydus Pharmaceuticals (USA)) |
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| Formula |
C5H4N4O
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| Exact mass |
136.0385
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| Mol weight |
136.1115
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| Structure |
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| Simcomp |
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| Class |
Cardiovascular agent
DG01503 Xanthine dehydrogenase inhibitor
Musculo-skeletal system agent
DG03130 Xanthin oxidase inhibitor
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
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| Remark |
| Therapeutic category: | 3943 |
| Product (DG00779): | D00224<JP/US> D07564<US> |
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| Efficacy |
Gout suppressant, Uric acid biosynthesis inhibitor, Xanthine oxidase inhibitor |
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| Disease |
Primary or secondary gout [DS: H01532] |
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| Target |
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| Pathway |
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| Interaction |
CYP inhibition: CYP1A2 [HSA: 1544]
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| Other map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M04 ANTIGOUT PREPARATIONS
M04A ANTIGOUT PREPARATIONS
M04AA Preparations inhibiting uric acid production
M04AA01 Allopurinol
D00224 Allopurinol (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antigout Agents
Allopurinol
D00224 Allopurinol (JP18/USP/INN)
Antineoplastics
Antineoplastic Adjuncts/Mitigators
Allopurinol
D00224 Allopurinol (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
394 Gout preparations
3943 Allopurinols
D00224 Allopurinol (JP18/USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01503 Xanthine dehydrogenase inhibitor
DG00779 Allopurinol
D00224 Allopurinol
Musculo-skeletal system agent
DG03130 Xanthin oxidase inhibitor
DG00779 Allopurinol
D00224 Allopurinol
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00779 Allopurinol
D00224 Allopurinol
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Xanthine dehydrogenase/oxidase
XDH
D00224 Allopurinol (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00224 Allopurinol
D00224 Allopurinol tablets
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00224
Drug groups [BR:br08330]
Cardiovascular agent
DG01503 Xanthine dehydrogenase inhibitor
DG00779 Allopurinol
Musculo-skeletal system agent
DG03130 Xanthin oxidase inhibitor
DG00779 Allopurinol
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00779 Allopurinol
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| Other DBs |
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| KCF data |
ATOM 10
1 C8y C 18.5315 -16.1687
2 C8y C 18.5315 -17.5678
3 C8y C 19.7490 -15.4662
4 C8x C 17.1967 -15.7414
5 N5x N 19.7490 -18.2703
6 N4x N 17.2026 -18.0068
7 N5x N 20.9548 -16.1687
8 O1a O 19.7490 -14.0673
9 N5x N 16.3773 -16.8711
10 C8x C 20.9548 -17.5678
BOND 11
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 3 8 1
8 4 9 2
9 5 10 2
10 6 9 1
11 7 10 1
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