| Entry |
|
|---|
| Name |
Captopril (JP18/USP/INN);
Apopril (TN);
Capoten (TN) |
|---|
| Product |
|
|---|
| Generic |
CAPTOPRIL (AMICI PHARMACEUTICALS LLC), CAPTOPRIL (Ajanta Pharma USA), CAPTOPRIL (American Health Packaging), CAPTOPRIL (Bryant Ranch Prepack), CAPTOPRIL (Bryant Ranch Prepack), CAPTOPRIL (Bryant Ranch Prepack), CAPTOPRIL (Bryant Ranch Prepack), CAPTOPRIL (Bryant Ranch Prepack), CAPTOPRIL (Bryant Ranch Prepack), CAPTOPRIL (Camber Pharmaceuticals), CAPTOPRIL (Golden State Medical Supply), CAPTOPRIL (Hikma Pharmaceuticals USA), CAPTOPRIL (Major Pharmaceuticals), CAPTOPRIL (PD-Rx Pharmaceuticals), CAPTOPRIL (SANDOZ), CAPTOPRIL (Solco Healthcare US) |
|---|
| Formula |
C9H15NO3S
|
|---|
| Exact mass |
217.0773
|
|---|
| Mol weight |
217.2853
|
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| Structure |
|
|---|
| Simcomp |
|
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| Class |
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
|
|---|
| Remark |
| Therapeutic category: | 2144 |
| Product (mixture): | D10276<US> |
|
|---|
| Efficacy |
Antihypertensive, Angiotensin-converting enzyme inhibitor |
|---|
| Disease |
|
|---|
| Target |
|
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| Pathway |
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| Interaction |
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| Structure map |
| map07217 | Renin-angiotensin system inhibitors |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
C09A ACE INHIBITORS, PLAIN
C09AA ACE inhibitors, plain
C09AA01 Captopril
D00251 Captopril (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Angiotensin-converting Enzyme (ACE) Inhibitors
Captopril
D00251 Captopril (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
214 Antihypertensives
2144 Angiotensin converting enzyme inhibitors
D00251 Captopril (JP18/USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01925 Renin-angiotensin system inhibitor
DG01501 Angiotensin-converting enzyme inhibitor
D00251 Captopril
DG03231 Antihypertensive
DG01501 Angiotensin-converting enzyme inhibitor
D00251 Captopril
Drug classes [BR:br08332]
Cardiovascular agent
DG01501 Angiotensin-converting enzyme inhibitor
D00251 Captopril
DG03231 Antihypertensive
D00251 Captopril
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Peptidyl-dipeptidases
ACE (CD143)
D00251 Captopril (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00251 Captopril
Prodrugs [br08324.html]
D00251
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| Other DBs |
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| KCF data |
ATOM 14
1 C1x C 30.3001 -29.3105
2 C1x C 30.7108 -30.6489
3 C1x C 32.1107 -30.6718
4 C1y C 32.5650 -29.3476
5 N1y N 31.4460 -28.5062
6 C5a C 31.4460 -27.1062
7 O5a O 32.6533 -26.4091
8 C1c C 30.2145 -26.3954
9 C1b C 29.0237 -27.0832
10 S1a S 27.8339 -26.3964
11 C6a C 33.8944 -28.9394
12 O6a O 35.2472 -29.5220
13 O6a O 33.8637 -27.5503
14 C1a C 30.2142 -24.9902
BOND 14
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 5 6 1
7 6 7 2
8 6 8 1
9 8 9 1
10 9 10 1
11 4 11 1 #Down
12 11 12 1
13 11 13 2
14 8 14 1 #Up
|
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