| Entry |
|
|---|
| Name |
Chlordiazepoxide (JP18/USP/INN);
Libritabs (TN) |
|---|
| Formula |
C16H14ClN3O
|
|---|
| Exact mass |
299.0825
|
|---|
| Mol weight |
299.7549
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01567 GABA-A receptor agonist
DG01914 Anxiolytics, benzodiazepine derivatives
|
|---|
| Remark |
| Therapeutic category: | 1124 |
| Product (DG00908): | D00267<JP> D00693<US> |
| Product (mixture): | D10207<US> |
|
|---|
| Efficacy |
Antianxiety, Minor tranquilizer, Sedative-hypnotic |
|---|
| Comment |
Benzodiazepine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05B ANXIOLYTICS
N05BA Benzodiazepine derivatives
N05BA02 Chlordiazepoxide
D00267 Chlordiazepoxide (JP18/USP/INN) <JP>
USP drug classification [BR:br08302]
Anxiolytics
Benzodiazepines
Chlordiazepoxide
D00267 Chlordiazepoxide (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
112 Hypnotics and sedatives, anxiolytics
1124 Benzodiazepins
D00267 Chlordiazepoxide (JP18/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01567 GABA-A receptor agonist
DG00908 Chlordiazepoxide
D00267 Chlordiazepoxide
DG01914 Anxiolytics, benzodiazepine derivatives
DG00908 Chlordiazepoxide
D00267 Chlordiazepoxide
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00267 Chlordiazepoxide (JP18/USP/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00267 Chlordiazepoxide
D00267 Chlordiazepoxide tablets
D00267 Chlordiazepoxide powder
Narcotics and psychotropics in Japan [br08308.html]
Psychotropics by Control Act Article 2 Table 31 (10 substances)
D00267
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01567 GABA-A receptor agonist
DG00908 Chlordiazepoxide
DG01914 Anxiolytics, benzodiazepine derivatives
DG00908 Chlordiazepoxide
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C2y C 15.8134 -15.8294
2 C8y C 14.9713 -14.7198
3 C8y C 15.3065 -13.3630
4 N2x N 16.5675 -12.7849
5 N2y N 17.2192 -15.8546 #+
6 C2y C 17.8211 -13.4072
7 C1x C 18.1076 -14.7759
8 C8x C 14.2994 -12.3946
9 C8x C 12.9574 -12.7827
10 C8y C 12.6222 -14.1395
11 C8x C 13.6293 -15.1076
12 C1a C 20.1966 -12.9099
13 N1b N 18.8652 -12.4728
14 X Cl 11.2574 -14.5339
15 C8y C 15.1789 -17.0791
16 C8x C 13.7773 -17.0791
17 O3a O 17.7925 -17.0976 #-
18 C8x C 13.0773 -18.2916
19 C8x C 13.7773 -19.5040
20 C8x C 15.1789 -19.5040
21 C8x C 15.8789 -18.2916
BOND 23
1 3 4 1
2 1 5 2
3 4 6 2
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 12 13 1
14 6 13 1
15 10 14 1
16 1 15 1
17 15 16 1
18 5 17 1
19 16 18 2
20 18 19 1
21 19 20 2
22 20 21 1
23 15 21 2
|
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