| Entry |
|
|---|
| Name |
Clofibrate (JP18/USP/INN);
Atromid-S (TN) |
|---|
| Formula |
C12H15ClO3
|
|---|
| Exact mass |
242.071
|
|---|
| Mol weight |
242.6987
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 2183 |
| Product (DG00358): | D00279<JP> |
|
|---|
| Efficacy |
Antihyperlipidemic, Triglyceride synthesis inhibitor, Peroxisome proliferator-activated receptor (PPAR) alpha agonist |
|---|
| Comment |
Clofibrate derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04920 | Adipocytokine signaling pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07222 | Peroxisome proliferator-activated receptor (PPAR) agonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C10 LIPID MODIFYING AGENTS
C10A LIPID MODIFYING AGENTS, PLAIN
C10AB Fibrates
C10AB01 Clofibrate
D00279 Clofibrate (JP18/USP/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
218 Hyperlipidemia agents
2183 Clofibrates
D00279 Clofibrate (JP18/USP/INN)
Drug groups [BR:br08330]
Hypolipidemic agent
DG01946 Hypolipidemic agent
DG01733 PPAR alpha agonist
DG01547 Fibrate
DG00358 Clofibrate
D00279 Clofibrate
Drug classes [BR:br08332]
Cardiovascular agent
DG01946 Hypolipidemic agent
D00279 Clofibrate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C1 (PPARA)
D00279 Clofibrate (JP18/USP/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00279 Clofibrate
D00279 Clofibrate capsules
Drug groups [BR:br08330]
Hypolipidemic agent
DG01946 Hypolipidemic agent
DG01733 PPAR alpha agonist
DG01547 Fibrate
DG00358 Clofibrate
|
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| Other DBs |
|
|---|
| KCF data |
ATOM 16
1 C8y C 22.6483 -14.4413
2 O2a O 23.9107 -13.7399
3 C1d C 25.1030 -14.4413
4 C7a C 26.2953 -13.7399
5 O7a O 27.5577 -14.4413
6 O6a O 26.2953 -12.3373
7 C1b C 28.7500 -13.7399
8 C1a C 29.9423 -14.4413
9 C8x C 21.4560 -13.7399
10 C8x C 20.1936 -14.4413
11 C8y C 20.1936 -15.8440
12 C8x C 21.3858 -16.5453
13 C8x C 22.6483 -15.8440
14 X Cl 19.0013 -16.4752
15 C1a C 24.1130 -15.4312
16 C1a C 26.0929 -15.4312
BOND 16
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 4 6 2
6 5 7 1
7 7 8 1
8 1 9 2
9 9 10 1
10 10 11 2
11 11 12 1
12 12 13 2
13 1 13 1
14 11 14 1
15 3 15 1
16 3 16 1
|
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