| Entry |
|
|---|
| Name |
Clonidine (JAN/USP/INN);
Catarpres-TTS (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C9H9Cl2N3
|
|---|
| Exact mass |
229.0174
|
|---|
| Mol weight |
230.0939
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01738 Centrally-acting antiadrenergic
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
DG03231 Antihypertensive
|
|---|
| Remark |
| Product (DG00249): | D00281<US> D00604<JP/US> |
|
|---|
| Efficacy |
Antihypertensive, alpha2-Adrenergic receptor agonist |
|---|
| Comment |
Imidazoline derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07215 | alpha-Adrenergic receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C02 ANTIHYPERTENSIVES
C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING
C02AC Imidazoline receptor agonists
C02AC01 Clonidine
D00281 Clonidine (JAN/USP/INN) <US>
N NERVOUS SYSTEM
N02 ANALGESICS
N02C ANTIMIGRAINE PREPARATIONS
N02CX Other antimigraine preparations
N02CX02 Clonidine
D00281 Clonidine (JAN/USP/INN) <US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EA Sympathomimetics in glaucoma therapy
S01EA04 Clonidine
D00281 Clonidine (JAN/USP/INN) <US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Alpha-adrenergic Agonists
Clonidine
D00281 Clonidine (JAN/USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01738 Centrally-acting antiadrenergic
DG00249 Clonidine
D00281 Clonidine
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
DG00249 Clonidine
D00281 Clonidine
DG03231 Antihypertensive
DG00249 Clonidine
D00281 Clonidine
Drug classes [BR:br08332]
Cardiovascular agent
DG03231 Antihypertensive
D00281 Clonidine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA2
D00281 Clonidine (JAN/USP/INN) <US>
Drug groups [BR:br08330]
Cardiovascular agent
DG01738 Centrally-acting antiadrenergic
DG00249 Clonidine
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
DG00249 Clonidine
DG03231 Antihypertensive
DG00249 Clonidine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 14
1 C8x C 8.2600 -20.5100
2 C8x C 8.2600 -21.9100
3 C8x C 9.4724 -22.6100
4 C8y C 10.6849 -21.9100
5 C8y C 10.6849 -20.5100
6 C8y C 9.4724 -19.8100
7 X Cl 11.8973 -22.6100
8 N1x N 13.1097 -21.9100
9 C2y C 13.1097 -20.5100
10 N2b N 11.8973 -19.8100
11 C1x C 14.4412 -22.3426
12 C1x C 15.2641 -21.2100
13 N1x N 14.4412 -20.0774
14 X Cl 9.4724 -18.4102
BOND 15
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 8 9 1
9 9 10 2
10 5 10 1
11 8 11 1
12 11 12 1
13 12 13 1
14 9 13 1
15 6 14 1
|
|---|
