| Entry |
|
|---|
| Name |
Droperidol (JP18/USP/INN);
Droleptan (TN);
Inapsine (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C22H22FN3O2
|
|---|
| Exact mass |
379.1696
|
|---|
| Mol weight |
379.4274
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
|
|---|
| Remark |
| Therapeutic category: | 1119 |
|
|---|
| Efficacy |
Anesthetic (intravenous), Anti-emetic, Antipsychotic |
|---|
| Comment |
Butyrophenone derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07031 | Antipsychotics - butyrophenones |
| map07213 | Dopamine receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05A ANTIPSYCHOTICS
N05AD Butyrophenone derivatives
N05AD08 Droperidol
D00308 Droperidol (JP18/USP/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
111 General anesthetics
1119 Others
D00308 Droperidol (JP18/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01478 Dopamine antagonist
DG01474 Dopamine D2-receptor antagonist
D00308 Droperidol
DG03200 Antipsychotic agent
DG01940 Butyrophenone derivative
D00308 Droperidol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D00308 Droperidol (JP18/USP/INN) <JP/US>
Dopamine
DRD2
D00308 Droperidol (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00308 Droperidol
|
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| Other DBs |
|
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| KCF data |
ATOM 28
1 N4y N 34.7898 -14.1599
2 C8y C 36.1337 -14.5455
3 C2y C 33.5782 -14.8648
4 C8y C 34.7636 -12.7484
5 C8y C 36.9382 -13.4028
6 C8x C 36.7369 -15.8127
7 C1x C 33.5782 -16.2626
8 C2x C 32.3726 -14.1599
9 N4x N 36.0849 -12.2909
10 O5x O 33.6158 -11.9504
11 C8x C 38.3329 -13.5172
12 C8x C 38.1331 -15.9387
13 C1x C 32.3726 -16.9615
14 C1x C 31.1553 -14.8648
15 C8x C 38.9302 -14.7851
16 N1y N 31.1612 -16.2626
17 C1b C 29.9498 -16.9615
18 C1b C 28.7325 -16.2626
19 C1b C 27.5210 -16.9615
20 C5a C 26.3037 -16.2626
21 C8y C 25.0923 -16.9615
22 O5a O 26.3037 -14.8648
23 C8x C 23.8807 -16.2626
24 C8x C 25.0923 -18.3593
25 C8x C 22.6693 -16.9615
26 C8x C 23.8866 -19.0642
27 C8y C 22.6752 -18.3652
28 X F 21.4636 -19.0699
BOND 31
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 1
7 3 8 2
8 4 9 1
9 4 10 2
10 5 11 1
11 6 12 2
12 7 13 1
13 8 14 1
14 11 15 2
15 13 16 1
16 16 17 1
17 17 18 1
18 18 19 1
19 19 20 1
20 20 21 1
21 20 22 2
22 21 23 2
23 21 24 1
24 23 25 1
25 24 26 2
26 25 27 2
27 27 28 1
28 5 9 1
29 12 15 1
30 14 16 1
31 26 27 1
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