| Entry |
|
|---|
| Name |
Famciclovir (JAN/USP/INN);
Famvir (TN) |
|---|
| Abbr |
FCV |
|---|
| Product |
|
|---|
| Generic |
FAMCICLOVIR (Apotex Corp.), FAMCICLOVIR (Aurobindo Pharma Limited), FAMCICLOVIR (AvKARE), FAMCICLOVIR (Camber Pharmaceuticals), FAMCICLOVIR (Macleods Pharmaceuticals Limited), FAMCICLOVIR (PD-Rx Pharmaceuticals), FAMCICLOVIR (Proficient Rx LP), FAMCICLOVIR (Proficient Rx LP), FAMCICLOVIR (Proficient Rx LP), FAMCICLOVIR (RPK Pharmaceuticals), FAMCICLOVIR (Rising Pharmaceuticals), FAMCICLOVIR (Teva Pharmaceuticals USA) |
|---|
| Formula |
C14H19N5O4
|
|---|
| Exact mass |
321.1437
|
|---|
| Mol weight |
321.3318
|
|---|
| Structure |
|
|---|
| Class |
Antiviral
DG02840 Anti-herpesvirus agent
|
|---|
| Remark |
| Therapeutic category: | 6250 |
|
|---|
| Efficacy |
Antiviral, DNA polymerase inhibitor |
|---|
| Disease |
Herpes labialis, Genital herpes [DS: H00365] Herpes zoster [DS: H00366] |
|---|
| Comment |
Active form of prodrug: Penciclovir [DR: D05407]
|
|---|
| Target |
Herpesvirus DNA polymerase [KO: K18964] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
J05AB09 Famciclovir
D00317 Famciclovir (JAN/USP/INN) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AD Antivirals
S01AD07 Famciclovir
D00317 Famciclovir (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antivirals
Antiherpetic Agents
Famciclovir
D00317 Famciclovir (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
625 Antivirals
6250 Antivirals
D00317 Famciclovir (JAN/USP/INN)
Drug groups [BR:br08330]
Antiviral
DG02840 Anti-herpesvirus agent
D00317 Famciclovir
Drug classes [BR:br08332]
Antiviral
DG02840 Anti-herpesvirus agent
D00317 Famciclovir
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D00317 Famciclovir (JAN/USP/INN) <JP/US>
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D00317 Famciclovir (JAN/USP/INN)
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D00317
Prodrugs [br08324.html]
D00317
|
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| Other DBs |
|
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| KCF data |
ATOM 23
1 C8y C 21.2800 -21.7700
2 C8y C 21.2800 -20.3700
3 N4y N 19.8800 -22.1900
4 N5x N 22.4700 -22.5400
5 N5x N 19.9500 -19.9500
6 C8x C 22.4700 -19.7400
7 C8x C 19.1100 -21.0700
8 C8y C 23.7300 -21.8400
9 N5x N 23.7300 -20.4400
10 N1a N 24.8500 -22.6100
11 C1b C 19.8800 -23.5900
12 C1b C 18.6900 -24.2900
13 C1c C 17.5000 -23.5900
14 C1b C 16.3100 -24.2900
15 C1b C 17.5000 -22.1900
16 O7a O 16.3100 -21.4900
17 O7a O 15.1200 -23.5900
18 C7a C 13.8600 -24.2900
19 C1a C 12.7400 -23.5900
20 O6a O 13.8600 -25.6900
21 C7a C 16.3214 -20.0900
22 O6a O 17.5308 -19.4048
23 C1a C 15.1062 -19.3752
BOND 24
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 4 8 2
8 6 9 2
9 8 10 1
10 5 7 2
11 8 9 1
12 3 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 13 15 1
17 15 16 1
18 14 17 1
19 17 18 1
20 18 19 1
21 18 20 2
22 16 21 1
23 21 22 2
24 21 23 1
|
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