 | | DRUG: Famotidine | |
| Entry |
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| Name |
Famotidine (JP18/USP/INN);
Fluxid (TN);
Pepcid (TN) |
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| Product |
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| Generic |
FAMOTIDINE (A-S Medication Solutions), FAMOTIDINE (A-S Medication Solutions), FAMOTIDINE (A-S Medication Solutions), FAMOTIDINE (A-S Medication Solutions), FAMOTIDINE (A-S Medication Solutions), FAMOTIDINE (A-S Medication Solutions), FAMOTIDINE (A-S Medication Solutions), FAMOTIDINE (A-S Medication Solutions), FAMOTIDINE (ANI Pharmaceuticals), FAMOTIDINE (Advanced Rx Pharmacy of Tennessee), FAMOTIDINE (Ajanta Pharma USA), FAMOTIDINE (Akorn), FAMOTIDINE (Alembic Pharmaceuticals Limited), FAMOTIDINE (Alembic Pharmaceuticals), FAMOTIDINE (American Health Packaging), FAMOTIDINE (Amneal Pharmaceuticals NY LLC), FAMOTIDINE (Aphena Pharma Solutions - Tennessee), FAMOTIDINE (Aphena Pharma Solutions - Tennessee), FAMOTIDINE (Ascend Laboratories), FAMOTIDINE (Ascend Laboratories), FAMOTIDINE (Ascend Laboratories), FAMOTIDINE (Ascent Pharmaceuticals), FAMOTIDINE (Athenex Pharmaceutical Division), FAMOTIDINE (Aurobindo Pharma Limited), FAMOTIDINE (AvKARE), FAMOTIDINE (AvPAK), FAMOTIDINE (AvPAK), FAMOTIDINE (Baxter Healthcare Corporation), FAMOTIDINE (Biocon Pharma), FAMOTIDINE (BluePoint Laboratories), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Bryant Ranch Prepack), FAMOTIDINE (Camber Pharmaceuticals), FAMOTIDINE (Camber Pharmaceuticals), FAMOTIDINE (Cardinal Health 107), FAMOTIDINE (Cardinal Health 107), FAMOTIDINE (Cardinal Health 107), FAMOTIDINE (Carlsbad Technology), FAMOTIDINE (Carnegie Pharmaceuticals LLC), FAMOTIDINE (Chartwell RX), FAMOTIDINE (DR. REDDY'S LABORATORIES), FAMOTIDINE (Denton Pharma), FAMOTIDINE (Direct_Rx), FAMOTIDINE (Direct_Rx), FAMOTIDINE (Direct_Rx), FAMOTIDINE (Dr.Reddy's Laboratories Limited), FAMOTIDINE (Fresenius Kabi USA), FAMOTIDINE (Fresenius Kabi USA), FAMOTIDINE (Fresenius Kabi USA), FAMOTIDINE (Golden State Medical Supply), FAMOTIDINE (Golden State Medical Supply), FAMOTIDINE (Golden State Medical Supply), FAMOTIDINE (Graviti Pharmaceuticals Private Limited), FAMOTIDINE (HF Acquisition Co LLC), FAMOTIDINE (Hikma Pharmaceuticals USA), FAMOTIDINE (Legacy Pharmaceutical Packaging), FAMOTIDINE (Legacy Pharmaceutical Packaging), FAMOTIDINE (Lifestar Pharma LLC), FAMOTIDINE (Lupin Pharmaceuticals), FAMOTIDINE (Lupin Pharmaceuticals), FAMOTIDINE (Major Pharmaceuticals), FAMOTIDINE (Mckesson Corporation DBA SKY Packaginng), FAMOTIDINE (Medical Purchasing Solutions), FAMOTIDINE (Medical Purchasing Solutions), FAMOTIDINE (Medsource Pharmaceuticals), FAMOTIDINE (Micro Labs Limited), FAMOTIDINE (Mylan Institutional LLC), FAMOTIDINE (NCS HealthCare of KY), FAMOTIDINE (NCS HealthCare of KY), FAMOTIDINE (Navinta LLC), FAMOTIDINE (NorthStar Rx LLC), FAMOTIDINE (Northstar Rx LLC), FAMOTIDINE (Northwind Pharmaceuticals), FAMOTIDINE (Northwind Pharmaceuticals), FAMOTIDINE (Northwind Pharmaceuticals), FAMOTIDINE (Northwind Pharmaceuticals), FAMOTIDINE (NuCare Pharmaceuticals), FAMOTIDINE (NuCare Pharmaceuticals), FAMOTIDINE (NuCare Pharmaceuticals), FAMOTIDINE (NuCare Pharmaceuticals), FAMOTIDINE (NuCare Pharmaceuticals), FAMOTIDINE (NuCare Pharmaceuticals), FAMOTIDINE (NuCare Pharmaceuticals), FAMOTIDINE (NuCare Pharmaceuticals), FAMOTIDINE (NuCare Pharmaceuticals), FAMOTIDINE (NuCare Pharmceuticals), FAMOTIDINE (PD-Rx Pharmaceuticals), FAMOTIDINE (PD-Rx Pharmaceuticals), FAMOTIDINE (PD-Rx Pharmaceuticals), FAMOTIDINE (PD-Rx Pharmaceuticals), FAMOTIDINE (PD-Rx Pharmaceuticals), FAMOTIDINE (PD-Rx Pharmaceuticals), FAMOTIDINE (PD-Rx Pharmaceuticals), FAMOTIDINE (Padagis US LLC), FAMOTIDINE (Preferred Pharmaceuticals), FAMOTIDINE (Preferred Pharmaceuticals), FAMOTIDINE (Preferred Pharmaceuticals), FAMOTIDINE (Preferred Pharmaceuticals), FAMOTIDINE (Preferred Pharmaceuticals), FAMOTIDINE (Preferred Pharmaceuticals), FAMOTIDINE (Preferred Pharmaceuticals), FAMOTIDINE (Preferred Pharmaceuticals), FAMOTIDINE (Proficient Rx LP), FAMOTIDINE (Proficient Rx LP), FAMOTIDINE (Proficient Rx LP), FAMOTIDINE (Proficient Rx LP), FAMOTIDINE (Proficient Rx LP), FAMOTIDINE (Proficient Rx LP), FAMOTIDINE (Proficient Rx LP), FAMOTIDINE (Proficient Rx LP), FAMOTIDINE (REMEDYREPACK), FAMOTIDINE (REMEDYREPACK), FAMOTIDINE (REMEDYREPACK), FAMOTIDINE (REMEDYREPACK), FAMOTIDINE (REMEDYREPACK), FAMOTIDINE (REMEDYREPACK), FAMOTIDINE (RPK Pharmaceuticals), FAMOTIDINE (RPK Pharmaceuticals), FAMOTIDINE (RPK Pharmaceuticals), FAMOTIDINE (RPK Pharmaceuticals), FAMOTIDINE (Redpharm Drug), FAMOTIDINE (Redpharm drug), FAMOTIDINE (ST. MARY'S MEDICAL PARK PHARMACY), FAMOTIDINE (ST. MARY'S MEDICAL PARK PHARMACY), FAMOTIDINE (St. Mary's Medical Park Pharmacy), FAMOTIDINE (St. Mary's Medical Park Pharmacy), FAMOTIDINE (Teva Pharmaceuticals USA), FAMOTIDINE (Upsher-Smith Laboratories), FAMOTIDINE (XLCare Pharmaceuticals), FAMOTIDINE (Zydus Lifesciences Limited), FAMOTIDINE (Zydus Lifesciences Limited), FAMOTIDINE (Zydus Pharmaceuticals USA), FAMOTIDINE (Zydus Pharmaceuticals USA), FAMOTIDINE (Zydus Pharmaceuticals USA), FAMOTIDINE (direct rx), FAMOTIDINE (direct rx), PEPCID (Bausch Health US LLC) |
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| Formula |
C8H15N7O2S3
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| Exact mass |
337.0449
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| Mol weight |
337.4454
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| Structure |
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| Class |
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG01481 Histamine receptor H2 antagonist
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
Transporter substrate
DG02854 SLC22A2 substrate
DG02860 SLC22A8 substrate
Transporter inhibitor
DG02863 SLC22A2 inhibitor
DG02881 SLC22A3 inhibitor
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| Remark |
| Therapeutic category: | 2325 |
| Product (mixture): | D11575<US> |
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| Efficacy |
Anti-ulcerative, H2 receptor antagonist |
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| Disease |
Duodenal ulcer [DS: H01634] Gastric ulcer [DS: H01634] Gastroesophageal reflux disease [DS: H01602] Zollinger-Ellison syndrome [DS: H01522] |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Metabolism |
Transporter: SLC22A2 [HSA: 6582], SLC22A8 [HSA: 9376]
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| Interaction |
CYP inhibition: CYP1A2 [HSA: 1544]
Transporter inhibition: SLC22A2 [HSA: 6582], SLC22A3 [HSA: 6581]
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| Structure map |
| map07227 | Histamine H2/H3 receptor agonists/antagonists |
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| Other map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A02 DRUGS FOR ACID RELATED DISORDERS
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
A02BA H2-receptor antagonists
A02BA03 Famotidine
D00318 Famotidine (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Gastrointestinal Agents
Histamine2 (H2) Receptor Antagonists
Famotidine
D00318 Famotidine (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
23 Digestive organ agents
232 Peptic ulcer agents
2325 H2 blockers
D00318 Famotidine (JP18/USP/INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for digestive organs
09 Histamine H2 receptor blocker containing drugs
D00318 Famotidine (JP18/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
First-class OTC drugs
Inorganic and organic chemicals
Famotidine
D00318 Famotidine (JP18/USP/INN)
Drug groups [BR:br08330]
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG01481 Histamine receptor H2 antagonist
D00318 Famotidine
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
D00318 Famotidine
Transporter substrate
DG02854 SLC22A2 substrate
D00318 Famotidine
DG02860 SLC22A8 substrate
D00318 Famotidine
Transporter inhibitor
DG02863 SLC22A2 inhibitor
D00318 Famotidine
DG02881 SLC22A3 inhibitor
D00318 Famotidine
Drug classes [BR:br08332]
Gastrointestinal agent
DG01481 Histamine receptor H2 antagonist
D00318 Famotidine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH2
D00318 Famotidine (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00318 Famotidine
D00318 Famotidine tablets
D00318 Famotidine powder
D00318 Famotidine injection
D00318 Famotidine for injection
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00318
Drug transporters
D00318
Rx-to-OTC switch list in the USA [br08315.html]
D00318
Rx-to-OTC switch list in Japan [br08314.html]
D00318
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| Other DBs |
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| KCF data |
ATOM 20
1 C1b C 21.2100 -23.8000
2 S2a S 22.4700 -23.1000
3 C1b C 23.6600 -23.8000
4 C1b C 24.8500 -23.1000
5 C2c C 26.1100 -23.8000
6 N2b N 27.3000 -23.1000
7 C8y C 20.0200 -23.1000
8 N5x N 20.0200 -21.7000
9 C8y C 18.6900 -21.2800
10 S2x S 17.8500 -22.4000
11 C8x C 18.6900 -23.5200
12 N2b N 18.2620 -19.9470
13 C2c C 16.9019 -19.6530
14 N1a N 15.9389 -20.7155
15 N1a N 16.4756 -18.3267
16 N1a N 26.1272 -25.1999
17 S4a S 28.5181 -23.7901
18 O3c O 29.6995 -23.0950
19 O3c O 28.4598 -25.1994
20 N1a N 29.7021 -24.5005
BOND 20
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 2
6 1 7 1
7 7 8 1
8 8 9 2
9 9 10 1
10 10 11 1
11 7 11 2
12 9 12 1
13 12 13 2
14 13 14 1
15 13 15 1
16 5 16 1
17 6 17 1
18 17 18 2
19 17 19 2
20 17 20 1
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