 | | DRUG: Fluocinonide | |
| Entry |
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| Name |
Fluocinonide (JP18/USP/INN);
Lidex (TN);
Vanos (TN) |
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| Product |
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| Generic |
FLUOCINONIDE (A-S Medication Solutions), FLUOCINONIDE (A-S Medication Solutions), FLUOCINONIDE (A-S Medication Solutions), FLUOCINONIDE (Amneal Pharmaceuticals NY LLC), FLUOCINONIDE (Asclemed USA), FLUOCINONIDE (Asclemed USA), FLUOCINONIDE (Bryant Ranch Prepack), FLUOCINONIDE (Bryant Ranch Prepack), FLUOCINONIDE (Bryant Ranch Prepack), FLUOCINONIDE (Bryant Ranch Prepack), FLUOCINONIDE (Bryant Ranch Prepack), FLUOCINONIDE (Bryant Ranch Prepack), FLUOCINONIDE (Bryant Ranch Prepack), FLUOCINONIDE (Bryant Ranch Prepack), FLUOCINONIDE (Bryant Ranch Prepack), FLUOCINONIDE (Bryant Ranch Prepack), FLUOCINONIDE (Bryant Ranch Prepack), FLUOCINONIDE (Cosette Pharmaceuticals), FLUOCINONIDE (Cosette Pharmaceuticals), FLUOCINONIDE (E. Fougera & Co. a division of Fougera Pharmaceuticals), FLUOCINONIDE (Encube Ethicals Private Limited), FLUOCINONIDE (Fougera Pharmaceuticals), FLUOCINONIDE (Fougera Pharmaceuticals), FLUOCINONIDE (Glasshouse Pharmaceuticals Limited Canada), FLUOCINONIDE (Glenmark Pharmaceuticals), FLUOCINONIDE (IPG PHARMACEUTICALS), FLUOCINONIDE (IPG PHARMACEUTICALS), FLUOCINONIDE (IPG PHARMACEUTICALS), FLUOCINONIDE (Lupin Pharmaceuticals), FLUOCINONIDE (Macleods Pharmaceuticals Limited), FLUOCINONIDE (Novel Laboratories), FLUOCINONIDE (NuCare Pharmaceuticals), FLUOCINONIDE (NuCare Pharmaceuticals), FLUOCINONIDE (NuCare Pharmaceuticals), FLUOCINONIDE (Padagis Israel Pharmaceuticals), FLUOCINONIDE (Preferred Pharmaceuticals), FLUOCINONIDE (Preferred Pharmaceuticals), FLUOCINONIDE (Proficient Rx LP), FLUOCINONIDE (RPK Pharmaceuticals), FLUOCINONIDE (RPK Pharmaceuticals), FLUOCINONIDE (RPK Pharmaceuticals), FLUOCINONIDE (Rising Pharmaceuticals), FLUOCINONIDE (Taro Pharmaceuticals U.S.A.), FLUOCINONIDE (Taro Pharmaceuticals U.S.A.), FLUOCINONIDE (Taro Pharmaceuticals U.S.A.), FLUOCINONIDE (Teva Pharmaceuticals USA), FLUOCINONIDE (Viona Pharmaceuticals), FLUOCINONIDE (Xiromed LLC), FLUOCINONIDE (Zydus Lifesciences Limited), FLUOCINONIDE (Zydus Lifesciences Limited), FLUOCINONIDE (Zydus Pharmaceuticals USA), FLUOCINONIDE CREAM (Amneal Pharmaceuticals NY LLC), FLUOCINONIDE CREAM (NuCare Pharmaceuticals), FLUOCINONIDE CREAM (NuCare Pharmceuticals), FLUOCINONIDE CREAM (Preferred Pharmaceuticals) |
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| Formula |
C26H32F2O7
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| Exact mass |
494.2116
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| Mol weight |
494.5249
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| Structure |
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| Simcomp |
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| Class |
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
Dermatological agent
DG03243 Atopic dermatitis agent
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| Remark |
| Therapeutic category: | 2646 |
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| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA11 Fluocinonide
D00325 Fluocinonide (JP18/USP/INN) <JP/US>
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AC Corticosteroids, potent (group III)
D07AC08 Fluocinonide
D00325 Fluocinonide (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Dermatological Agents
Dermatitis and Pruitus Agents
Glucocorticoids, High Potency
Fluocinonide
D00325 Fluocinonide (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
26 Epidermides
264 Analgesics, anti-itchings, astringents, anti-inflammatory agents
2646 Adrenocorticotropic hormones
D00325 Fluocinonide (JP18/USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
D00325 Fluocinonide
Dermatological agent
DG03243 Atopic dermatitis agent
D00325 Fluocinonide
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D00325 Fluocinonide
Dermatological agent
DG03243 Atopic dermatitis agent
D00325 Fluocinonide
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00325 Fluocinonide (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00325 Fluocinonide
Topical steroids potency [br08317.html]
Classification in the USA
D00325
Classification in Japan
D00325
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| Other DBs |
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| KCF data |
ATOM 35
1 C2x C 18.6900 -28.5600
2 C5x C 18.6900 -29.8900
3 C2x C 19.8800 -30.5900
4 C2y C 21.0700 -29.8900
5 C1z C 21.0700 -28.5600
6 C2x C 19.8800 -27.8600
7 C1y C 22.2600 -30.5900
8 C1x C 23.4500 -29.8900
9 C1y C 23.4500 -28.5600
10 C1z C 22.2600 -27.8600
11 C1y C 24.5700 -27.8600
12 C1z C 24.5700 -26.5300
13 C1x C 23.4500 -25.8300
14 C1y C 22.2600 -26.5300
15 C1x C 26.9500 -27.8600
16 C1y C 26.9500 -26.5300
17 C1z C 25.7600 -25.8300
18 O5x O 17.5700 -30.5900
19 C1a C 21.0700 -27.1600
20 X F 22.2600 -29.1900
21 O1a O 21.0700 -25.8300
22 C1a C 24.5700 -25.1300
23 C5a C 25.7600 -24.2200
24 O2x O 27.1600 -24.9200
25 O5a O 26.9500 -23.5200
26 C1b C 24.5700 -23.5200
27 O7a O 23.4500 -24.2200
28 O2x O 28.3500 -26.5300
29 C1z C 28.5600 -24.9200
30 C1a C 29.9600 -24.9200
31 C1a C 28.5600 -23.5200
32 X F 22.2600 -31.9900
33 C7a C 22.2138 -23.5629
34 C1a C 20.9972 -24.3229
35 O6a O 22.1654 -22.1902
BOND 39
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 2 18 2
22 5 19 1 #Up
23 10 20 1 #Down
24 14 21 1 #Up
25 12 22 1 #Up
26 17 23 1 #Up
27 17 24 1 #Down
28 23 25 2
29 23 26 1
30 26 27 1
31 16 28 1 #Down
32 24 29 1
33 29 28 1
34 29 30 1
35 29 31 1
36 7 32 1 #Down
37 27 33 1
38 33 34 1
39 33 35 2
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