| Entry |
|
|---|
| Name |
Ganciclovir (JAN/USP/INN);
Cytovene (TN);
Vitrasert (TN);
Zirgan (TN) |
|---|
| Product |
|
|---|
| Formula |
C9H13N5O4
|
|---|
| Exact mass |
255.0968
|
|---|
| Mol weight |
255.2306
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antiviral
DG02840 Anti-herpesvirus agent
DG01937 Anti-cytomegalovirus agent
|
|---|
| Remark |
| Therapeutic category: | 6250 |
| Product (DG00646): | D00333<JP/US> D04301<US> |
|
|---|
| Efficacy |
Antiviral, DNA polymerase inhibitor |
|---|
| Disease |
CMV retinitis, Prevention of CMV disease [DS: H00368] Acute herpetic keratitis [DS: H00365] |
|---|
| Target |
HCMV DNA polymerase [KO: K18964] Herpesvirus DNA polymerase [KO: K18964] |
|---|
| Pathway |
|
|---|
| Interaction |
|
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| Structure map |
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| Other map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
J05AB06 Ganciclovir
D00333 Ganciclovir (JAN/USP/INN) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AD Antivirals
S01AD09 Ganciclovir
D00333 Ganciclovir (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antivirals
Anti-cytomegalovirus (CMV) Agents
Ganciclovir
D00333 Ganciclovir (JAN/USP/INN)
Ophthalmic Agents
Ophthalmic Anti-Infectives
Antiviral, Ophthalmic
Ganciclovir
D00333 Ganciclovir (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
625 Antivirals
6250 Antivirals
D00333 Ganciclovir (JAN/USP/INN)
Drug groups [BR:br08330]
Antiviral
DG02840 Anti-herpesvirus agent
DG00646 Ganciclovir
D00333 Ganciclovir
DG01937 Anti-cytomegalovirus agent
DG00646 Ganciclovir
D00333 Ganciclovir
Drug classes [BR:br08332]
Antiviral
DG02840 Anti-herpesvirus agent
D00333 Ganciclovir
DG01937 Anti-cytomegalovirus agent
D00333 Ganciclovir
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D00333 Ganciclovir (JAN/USP/INN) <JP/US>
Prodrugs [br08324.html]
D00333
Drug groups [BR:br08330]
Antiviral
DG02840 Anti-herpesvirus agent
DG00646 Ganciclovir
DG01937 Anti-cytomegalovirus agent
DG00646 Ganciclovir
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
DG00646 Ganciclovir
|
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| Other DBs |
|
|---|
| KCF data |
ATOM 18
1 N4y N 23.5894 -15.7792
2 C8y C 24.8354 -15.3006
3 C8y C 24.8570 -13.9009
4 N5x N 23.5108 -13.5146
5 C8x C 22.7274 -14.6754
6 N5x N 26.2117 -15.9583
7 C8y C 27.3295 -15.2166
8 N4x N 27.2810 -13.8170
9 C8y C 26.0446 -13.1592
10 O5x O 26.0667 -11.7758
11 N1a N 28.5757 -15.8792
12 C1b C 23.5894 -17.1792
13 O2a O 22.3901 -17.8713
14 C1c C 21.1762 -17.1701
15 C1b C 19.9977 -17.8502
16 C1b C 21.1759 -15.7504
17 O1a O 19.9890 -15.0651
18 O1a O 18.8022 -17.1595
BOND 19
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 1 5 1
6 2 6 1
7 6 7 2
8 7 8 1
9 8 9 1
10 3 9 1
11 9 10 2
12 7 11 1
13 1 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 14 16 1
18 16 17 1
19 15 18 1
|
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