| Entry |
|
|---|
| Name |
Melphalan (JP18/USP/INN);
Alkeran (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C13H18Cl2N2O2
|
|---|
| Exact mass |
304.0745
|
|---|
| Mol weight |
305.2002
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antineoplastic
DG01677 Alkylating agent
DG01678 Nitrogen mustard analog
|
|---|
| Remark |
| Therapeutic category: | 4219 |
| Product (DG00676): | D00369<JP/US> D08173<US> |
|
|---|
| Efficacy |
Antineoplastic, Alkylating agent |
|---|
| Disease |
Multiple myeloma [DS: H00010] Carcinoma of the ovary [DS: H00027] |
|---|
| Target |
DNA |
|---|
| Interaction |
|
|---|
| Structure map |
| map07040 | Antineoplastics - alkylating agents |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01A ALKYLATING AGENTS
L01AA Nitrogen mustard analogues
L01AA03 Melphalan
D00369 Melphalan (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antineoplastics
Alkylating Agents
Melphalan
D00369 Melphalan (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
42 Antineoplastics
421 Alkylating agents
4219 Others
D00369 Melphalan (JP18/USP/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01677 Alkylating agent
DG01678 Nitrogen mustard analog
DG00676 Melphalan
D00369 Melphalan
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00369 Melphalan
Drug groups [BR:br08330]
Antineoplastic
DG01677 Alkylating agent
DG01678 Nitrogen mustard analog
DG00676 Melphalan
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 19
1 C8y C 24.0484 -21.2669
2 N1c N 25.2588 -21.9595
3 C8x C 22.8382 -21.9595
4 C8x C 24.0484 -19.8647
5 C1b C 25.2588 -23.3618
6 C1b C 26.4750 -21.2669
7 C8x C 21.6220 -21.2669
8 C8x C 22.8382 -19.1606
9 C8y C 21.6279 -19.8763
10 C1b C 20.4175 -19.1723
11 C1c C 19.2073 -19.8763
12 C6a C 17.9911 -19.1723
13 N1a N 19.2073 -21.2729
14 O6a O 16.7866 -19.8763
15 O6a O 17.9911 -17.7699
16 C1b C 26.4782 -19.8929
17 X Cl 27.7035 -19.1890
18 C1b C 24.0287 -24.0718
19 X Cl 24.0283 -25.4754
BOND 19
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 4 8 2
8 7 9 2
9 9 10 1
10 10 11 1
11 11 12 1
12 11 13 1 #Down
13 12 14 1
14 12 15 2
15 8 9 1
16 6 16 1
17 16 17 1
18 5 18 1
19 18 19 1
|
|---|
