 | | DRUG: Temazepam | |
| Entry |
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| Name |
Temazepam (USP/INN);
Restoril (TN) |
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| Product |
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| Generic |
TEMAZEPAM (A-S Medication Solutions), TEMAZEPAM (Actavis Pharma), TEMAZEPAM (Advanced Rx Pharmacy of Tennessee), TEMAZEPAM (Advanced Rx Pharmacy of Tennessee), TEMAZEPAM (Alembic Pharmaceuticals Limited), TEMAZEPAM (Alembic Pharmaceuticals), TEMAZEPAM (Amneal Pharmaceuticals LLC), TEMAZEPAM (Amneal Pharmaceuticals of New York LLC), TEMAZEPAM (Aphena Pharma Solutions - Tennessee), TEMAZEPAM (Aphena Pharma Solutions - Tennessee), TEMAZEPAM (Aphena Pharma Solutions - Tennessee), TEMAZEPAM (Aphena Pharma Solutions - Tennessee), TEMAZEPAM (Aphena Pharma Solutions - Tennessee), TEMAZEPAM (Aphena Pharma Solutions - Tennessee), TEMAZEPAM (Ascend Laboratories), TEMAZEPAM (AvPAK), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Bryant Ranch Prepack), TEMAZEPAM (Direct Rx), TEMAZEPAM (DirectRX), TEMAZEPAM (Golden State Medical Supply), TEMAZEPAM (Major Pharmaceuticals), TEMAZEPAM (McKesson Corporation dba SKY Packaging), TEMAZEPAM (NuCare Pharmaceuticals), TEMAZEPAM (NuCare Pharmaceuticals), TEMAZEPAM (PD-Rx Pharmaceuticals), TEMAZEPAM (PD-Rx Pharmaceuticals), TEMAZEPAM (Preferred Pharmaceuticals), TEMAZEPAM (Preferred Pharmaceuticals), TEMAZEPAM (Preferred Pharmaceuticals), TEMAZEPAM (Proficient Rx LP), TEMAZEPAM (Proficient Rx LP), TEMAZEPAM (Proficient Rx LP), TEMAZEPAM (Proficient Rx LP), TEMAZEPAM (Quality Care Products LLC), TEMAZEPAM (REMEDYREPACK), TEMAZEPAM (REMEDYREPACK), TEMAZEPAM (REMEDYREPACK), TEMAZEPAM (REMEDYREPACK), TEMAZEPAM (REMEDYREPACK), TEMAZEPAM (Solco Healthcare U.S.), TEMAZEPAM (Sun Pharmaceutical Industries) |
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| Formula |
C16H13ClN2O2
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| Exact mass |
300.0666
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| Mol weight |
300.7396
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| Structure |
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| Simcomp |
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| Class |
Neuropsychiatric agent
DG01835 Benzodiazepine sedative-hypnotics
DG03202 Hypnotic
DG01567 GABA-A receptor agonist
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| Remark |
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| Efficacy |
Minor tranquilizer |
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| Disease |
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| Comment |
Temazepam is metabolite of Diazepam.
Benzodiazepine derivative
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05C HYPNOTICS AND SEDATIVES
N05CD Benzodiazepine derivatives
N05CD07 Temazepam
D00370 Temazepam (USP/INN) <US>
USP drug classification [BR:br08302]
Sleep Disorder Agents
Sleep Promoting Agents
Temazepam
D00370 Temazepam (USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01835 Benzodiazepine sedative-hypnotics
D00370 Temazepam
DG03202 Hypnotic
D00370 Temazepam
DG01567 GABA-A receptor agonist
D00370 Temazepam
Drug classes [BR:br08332]
Neuropsychiatric agent
DG03202 Hypnotic
D00370 Temazepam
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00370 Temazepam (USP/INN) <US>
Narcotics and psychotropics in Japan [br08308.html]
Psychotropics by Cabinet order Article 3 (78 substances)
D00370
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| Other DBs |
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| KCF data |
ATOM 21
1 C2y C 17.3534 -8.3394
2 C8y C 16.5113 -7.2298
3 C8y C 16.8465 -5.8730
4 N1y N 18.1075 -5.2949
5 N2x N 18.7592 -8.3646
6 C5x C 19.3611 -5.9172
7 C1y C 19.6476 -7.2859
8 C8x C 15.8394 -4.9046
9 C8x C 14.4974 -5.2927
10 C8y C 14.1622 -6.6495
11 C8x C 15.1693 -7.6176
12 O1a O 20.9788 -7.7230
13 O5x O 20.4052 -4.9828
14 X Cl 12.7974 -7.0439
15 C8y C 16.7189 -9.5891
16 C8x C 15.3173 -9.5891
17 C8x C 14.6173 -10.8016
18 C8x C 15.3173 -12.0140
19 C8x C 16.7189 -12.0140
20 C8x C 17.4189 -10.8016
21 C1a C 18.1075 -3.8949
BOND 23
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 1
14 6 13 2
15 10 14 1
16 1 15 1
17 15 16 1
18 16 17 2
19 17 18 1
20 18 19 2
21 19 20 1
22 15 20 2
23 4 21 1
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