| Entry |
|
|---|
| Name |
Triamcinolone (JP18/USP/INN);
Aristocort (TN);
Kenacort (TN) |
|---|
| Formula |
C21H27FO6
|
|---|
| Exact mass |
394.1792
|
|---|
| Mol weight |
394.4339
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
Dermatological agent
DG03243 Atopic dermatitis agent
|
|---|
| Remark |
| Therapeutic category: | 2454 |
| Product (DG00010): | D00385<JP> D00983<JP/US> |
|
|---|
| Efficacy |
Antiasthmatic, Anti-inflammatory, Antirheumatic, Glucocorticoid receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A01 STOMATOLOGICAL PREPARATIONS
A01A STOMATOLOGICAL PREPARATIONS
A01AC Corticosteroids for local oral treatment
A01AC01 Triamcinolone
D00385 Triamcinolone (JP18/USP/INN) <JP>
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA12 Triamcinolone
D00385 Triamcinolone (JP18/USP/INN) <JP>
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AB Corticosteroids, moderately potent (group II)
D07AB09 Triamcinolone
D00385 Triamcinolone (JP18/USP/INN) <JP>
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XB Corticosteroids, moderately potent, other combinations
D07XB02 Triamcinolone
D00385 Triamcinolone (JP18/USP/INN) <JP>
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB08 Triamcinolone
D00385 Triamcinolone (JP18/USP/INN) <JP>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD11 Triamcinolone
D00385 Triamcinolone (JP18/USP/INN) <JP>
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
R03BA Glucocorticoids
R03BA06 Triamcinolone
D00385 Triamcinolone (JP18/USP/INN) <JP>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA05 Triamcinolone
D00385 Triamcinolone (JP18/USP/INN) <JP>
USP drug classification [BR:br08302]
Dental and Oral Agents
Triamcinolone
D00385 Triamcinolone (JP18/USP/INN)
Hormonal Agents, Stimulant/Replacement/Modifying (Adrenal)
Triamcinolone
D00385 Triamcinolone (JP18/USP/INN)
Respiratory Tract/Pulmonary Agents
Anti-inflammatories, Inhaled Corticosteroids
Triamcinolone
D00385 Triamcinolone (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
245 Adrenal hormone preparations
2454 Fluorinated adrenocorticotropic hormones
D00385 Triamcinolone (JP18/USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00010 Triamcinolone
D00385 Triamcinolone
Dermatological agent
DG03243 Atopic dermatitis agent
D00385 Triamcinolone
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D00385 Triamcinolone
Dermatological agent
DG03243 Atopic dermatitis agent
D00385 Triamcinolone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00385 Triamcinolone (JP18/USP/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00385 Triamcinolone
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00010 Triamcinolone
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 28
1 C2x C 14.0000 -26.6700
2 C5x C 14.0000 -28.0700
3 C2x C 15.2124 -28.7700
4 C2y C 16.4249 -28.0700
5 C1z C 16.4249 -26.6700
6 C2x C 15.2124 -25.9700
7 C1x C 17.6373 -28.7700
8 C1x C 18.8497 -28.0700
9 C1y C 18.8497 -26.6700
10 C1z C 17.6373 -25.9700
11 C1y C 20.0622 -25.9700
12 C1z C 20.0622 -24.5700
13 C1x C 18.8497 -23.8700
14 C1y C 17.6373 -24.5700
15 C1x C 22.4870 -25.9700
16 C1y C 22.4870 -24.5700
17 C1z C 21.2746 -23.8700
18 O5x O 12.7876 -28.7700
19 C1a C 16.4249 -25.2700
20 X F 17.6373 -27.3700
21 O1a O 16.4269 -23.8712
22 C1a C 20.0622 -23.1700
23 C5a C 21.2746 -22.1900
24 O1a O 22.6970 -22.9600
25 O1a O 23.6866 -23.8773
26 O5a O 22.4911 -21.4877
27 C1b C 20.0662 -21.4923
28 O1a O 18.8727 -22.1816
BOND 31
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 2 18 2
22 5 19 1 #Up
23 10 20 1 #Down
24 14 21 1 #Up
25 12 22 1 #Up
26 17 23 1 #Up
27 17 24 1 #Down
28 16 25 1 #Down
29 23 26 2
30 23 27 1
31 27 28 1
|
|---|
