| Entry |
|
|---|
| Name |
Zalcitabine (JAN/USP/INN);
Hivid (TN) |
|---|
| Abbr |
ddC |
|---|
| Formula |
C9H13N3O3
|
|---|
| Exact mass |
211.0957
|
|---|
| Mol weight |
211.2178
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antiviral
DG01890 Nucleoside reverse transcriptase inhibitor (NRTI)
DG01440 Arabinofuranosyl type antiviral
DG03107 Anti-HIV agent
DG01656 HIV reverse transcriptase inhibitor
Transporter substrate
DG02859 SLC22A6 substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiviral, Reverse transcriptase inhibitor |
|---|
| Target |
HIV-1 reverse transcriptase [KO: K24802] |
|---|
| Pathway |
|
|---|
| Metabolism |
Transporter: SLC22A6 [HSA: 9356]
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
J05AF03 Zalcitabine
D00412 Zalcitabine (JAN/USP/INN)
Drug groups [BR:br08330]
Antiviral
DG01890 Nucleoside reverse transcriptase inhibitor (NRTI)
D00412 Zalcitabine
DG01440 Arabinofuranosyl type antiviral
D00412 Zalcitabine
DG03107 Anti-HIV agent
DG01656 HIV reverse transcriptase inhibitor
D00412 Zalcitabine
Transporter substrate
DG02859 SLC22A6 substrate
D00412 Zalcitabine
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
HIV reverse transcriptase inhibitor
D00412 Zalcitabine (JAN/USP/INN)
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
HIV reverse transcriptase inhibitor
D00412 Zalcitabine (JAN/USP/INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug transporters
D00412
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 15
1 C1x C 18.1827 -18.2480
2 C1y C 18.5900 -16.9111
3 O2x O 17.4593 -16.0809
4 C1y C 16.3457 -16.9339
5 C1x C 16.7800 -18.2622
6 N4y N 19.7751 -16.1976
7 C8y C 20.9746 -16.8869
8 N5x N 22.2298 -16.1727
9 C8y C 22.2156 -14.7700
10 C8x C 21.0162 -14.0808
11 C8x C 19.7609 -14.7950
12 O5x O 20.9888 -18.2895
13 N1a N 23.4007 -14.0565
14 C1b C 15.1463 -16.2446
15 O1a O 13.9611 -16.9581
BOND 16
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 2 6 1 #Up
7 6 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 10 11 2
12 6 11 1
13 7 12 2
14 9 13 1
15 4 14 1 #Up
16 14 15 1
|
|---|
