| Entry |
|
|---|
| Name |
Oxaprozin (JP18/USP/INN);
Daypro (TN) |
|---|
| Product |
|
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| Generic |
OXAPROZIN (Amneal Pharmaceuticals NY LLC), OXAPROZIN (Bryant Ranch Prepack), OXAPROZIN (Bryant Ranch Prepack), OXAPROZIN (Bryant Ranch Prepack), OXAPROZIN (Bryant Ranch Prepack), OXAPROZIN (Chartwell RX), OXAPROZIN (Dr. Reddy's Laboratories Limited), OXAPROZIN (Eon Labs), OXAPROZIN (Greenstone LLC), OXAPROZIN (ST MARY'S MEDICAL PARK PHARMACY), OXAPROZIN (St Mary's Medical Park Pharmacy), OXAPROZIN (St. Mary's Medical Park Pharmacy) |
|---|
| Formula |
C18H15NO3
|
|---|
| Exact mass |
293.1052
|
|---|
| Mol weight |
293.3166
|
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| Structure |
|
|---|
| Simcomp |
|
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| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
|
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| Remark |
| Therapeutic category: | 1149 |
|
|---|
| Efficacy |
Analgesic, Anti-inflammatory, COX inhibitor |
|---|
| Disease |
Rheumatoid arthritis [DS: H00630] Juvenile rheumatoid arthritis [DS: H01672] |
|---|
| Comment |
Propionic acid derivative
|
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| Target |
|
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| Pathway |
|
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| Interaction |
|
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| Structure map |
| map07112 | 1,2-Diphenyl substitution family |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AE Propionic acid derivatives
M01AE12 Oxaprozin
D00463 Oxaprozin (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Analgesics
Nonsteroidal Anti-inflammatory Drugs
Oxaprozin
D00463 Oxaprozin (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
114 Antipyretics and analgesics, anti-inflammatory agents
1149 Others
D00463 Oxaprozin (JP18/USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01908 Anti-inflammatory drug, propionic acid derivatives
D00463 Oxaprozin
Drug classes [BR:br08332]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
D00463 Oxaprozin
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D00463 Oxaprozin (JP18/USP/INN) <JP/US>
PTGS2 (COX2)
D00463 Oxaprozin (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00463 Oxaprozin
|
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| Other DBs |
|
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| KCF data |
ATOM 22
1 C8y C 25.8557 -17.0142
2 C1b C 27.2577 -17.0142
3 N5x N 25.0145 -15.8927
4 C8y C 23.7060 -16.3132
5 C8y C 23.7060 -17.7152
6 O2x O 25.0145 -18.1358
7 C8x C 20.0609 -14.2103
8 C8x C 20.0609 -15.6123
9 C8x C 21.2760 -16.3132
10 C8y C 22.4910 -15.6123
11 C8x C 22.4910 -14.2103
12 C8x C 21.2760 -13.5093
13 C8x C 20.0609 -18.4162
14 C8x C 20.0609 -19.8181
15 C8x C 21.2760 -20.5191
16 C8x C 22.4910 -19.8181
17 C8y C 22.4910 -18.4162
18 C8x C 21.2760 -17.7152
19 C1b C 27.9586 -15.8000
20 C6a C 29.3606 -15.8000
21 O6a O 30.0620 -14.5852
22 O6a O 30.0612 -17.0135
BOND 24
1 1 2 1
2 1 3 2
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 1
7 7 8 2
8 8 9 1
9 9 10 2
10 10 11 1
11 11 12 2
12 7 12 1
13 10 4 1
14 13 14 2
15 14 15 1
16 15 16 2
17 16 17 1
18 17 18 2
19 13 18 1
20 17 5 1
21 2 19 1
22 19 20 1
23 20 21 1
24 20 22 2
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