| Entry |
|
|---|
| Name |
Pancuronium bromide (JP18/USP/INN);
Pavulon (TN) |
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| Formula |
C35H60N2O4. 2Br
|
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| Exact mass |
730.292
|
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| Mol weight |
732.6699
|
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| Structure |
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| Simcomp |
|
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| Class |
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
DG01742 Quaternary ammonium compound type muscle relaxant
|
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| Remark |
|
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| Efficacy |
Anesthetic (adjunct), Neuromuscular blocking agent |
|---|
| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
| map07221 | Nicotinic cholinergic receptor antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M03 MUSCLE RELAXANTS
M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
M03AC Other quaternary ammonium compounds
M03AC01 Pancuronium
D00492 Pancuronium bromide (JP18/USP/INN)
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
DG00769 Pancuronium
D00492 Pancuronium bromide
DG01742 Quaternary ammonium compound type muscle relaxant
DG00769 Pancuronium
D00492 Pancuronium bromide
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRN (neuronal type)
D00492 Pancuronium bromide (JP18/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00492 Pancuronium bromide
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
DG00769 Pancuronium
DG01742 Quaternary ammonium compound type muscle relaxant
DG00769 Pancuronium
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| Other DBs |
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| KCF data |
ATOM 43
1 C1y C 26.8959 -20.5388
2 C1y C 25.7302 -21.2091
3 C1z C 26.9135 -19.1864
4 C1x C 29.2452 -20.4979
5 C1y C 24.5586 -20.5214
6 C1x C 25.7302 -22.5673
7 C1y C 28.0968 -18.5219
8 C1x C 25.7535 -18.4928
9 C1a C 26.9426 -17.8924
10 C1y C 29.2626 -19.2155
11 C1z C 23.3752 -21.1917
12 C1x C 24.5702 -19.1690
13 C1x C 24.5469 -23.2435
14 O7a O 28.1083 -16.7963
15 N2y N 30.4459 -18.5452 #+
16 C1y C 23.3693 -22.5616
17 C1x C 22.1977 -20.5155
18 C1a C 23.2934 -19.9559
19 C7a C 26.9367 -16.0967
20 C1x C 31.6118 -19.2448
21 C1x C 30.4576 -17.1929
22 C1a C 30.4518 -20.1600
23 C1x C 22.1977 -23.2378
24 C1y C 21.0260 -21.1917
25 C1a C 25.7476 -16.7672
26 O6a O 26.9542 -14.7386
27 C1x C 32.7951 -18.5802
28 C1x C 31.6409 -16.5224
29 C1y C 21.0260 -22.5616
30 N2y N 19.7027 -20.3114 #+
31 C1x C 32.8125 -17.2220
32 O7a O 19.8427 -23.2378
33 C1x C 19.6386 -18.9591
34 C1x C 18.5311 -20.9935
35 C1a C 20.8860 -18.7781
36 C7a C 19.8427 -24.5959
37 C1x C 18.5311 -18.2771
38 C1x C 17.3537 -20.3174
39 C1a C 18.6653 -25.2778
40 O6a O 21.0260 -25.2778
41 C1x C 17.3594 -18.9591
42 X Br 19.7843 -16.9191 #-
43 X Br 31.0056 -22.2866 #-
BOND 46
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 3 9 1 #Up
9 4 10 1
10 5 11 1
11 5 12 1
12 6 13 1
13 7 14 1 #Up
14 10 15 1 #Up
15 11 16 1
16 11 17 1
17 11 18 1 #Up
18 14 19 1
19 15 20 1
20 15 21 1
21 15 22 1
22 16 23 1
23 17 24 1
24 19 25 1
25 19 26 2
26 20 27 1
27 21 28 1
28 23 29 1
29 24 30 1 #Up
30 27 31 1
31 29 32 1 #Down
32 30 33 1
33 30 34 1
34 30 35 1
35 32 36 1
36 33 37 1
37 34 38 1
38 36 39 1
39 36 40 2
40 37 41 1
41 7 10 1
42 8 12 1
43 13 16 1
44 24 29 1
45 28 31 1
46 38 41 1
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