| Entry |
|
|---|
| Name |
Pentobarbital (USP/INN);
Nembutal (TN) |
|---|
| Formula |
C11H18N2O3
|
|---|
| Exact mass |
226.1317
|
|---|
| Mol weight |
226.2722
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG01567 GABA-A receptor agonist
|
|---|
| Remark |
| Product (DG00915): | D00500<US> D02253<JP> |
|
|---|
| Efficacy |
Sedative-hypnotic |
|---|
| Comment |
Barbiturates
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05C HYPNOTICS AND SEDATIVES
N05CA Barbiturates, plain
N05CA01 Pentobarbital
D00499 Pentobarbital (USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG00915 Pentobarbital
D00499 Pentobarbital
DG01567 GABA-A receptor agonist
DG00915 Pentobarbital
D00499 Pentobarbital
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00499 Pentobarbital (USP/INN)
Narcotics and psychotropics in Japan [br08308.html]
Psychotropics by Control Act Article 2 Table 31 (10 substances)
D00499
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01837 Barbiturate sedative-hypnotics
DG00915 Pentobarbital
DG01567 GABA-A receptor agonist
DG00915 Pentobarbital
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 16
1 C1z C 24.3484 -19.3667
2 C5x C 23.1527 -18.6842
3 C5x C 24.3484 -20.7840
4 C1c C 25.7366 -19.3608
5 C1b C 24.3367 -17.9610
6 N1x N 21.9277 -19.3667
7 O5x O 23.1527 -17.2902
8 N1x N 23.1527 -21.4840
9 O5x O 25.5616 -21.4840
10 C1b C 26.4307 -18.1476
11 C1a C 26.4424 -20.5741
12 C1a C 25.5442 -17.2435
13 C5x C 21.9277 -20.7840
14 C1b C 27.8247 -18.1476
15 O5x O 20.7086 -21.4840
16 C1a C 28.5246 -16.9402
BOND 16
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 1
6 2 7 2
7 3 8 1
8 3 9 2
9 4 10 1
10 4 11 1
11 5 12 1
12 6 13 1
13 10 14 1
14 13 15 2
15 14 16 1
16 8 13 1
|
|---|
