| Entry |
|
|---|
| Name |
Phenobarbital (JP18/USP/INN);
Luminal (TN) |
|---|
| Formula |
C12H12N2O3
|
|---|
| Exact mass |
232.0848
|
|---|
| Mol weight |
232.2353
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Product (DG00845): | D00506<JP> D00701<JP/US> |
| Product (mixture): | D07583<JP> |
|
|---|
| Efficacy |
Antianxiety, Anticonvulsant, Sedative-hypnotic |
|---|
| Comment |
Barbiturates
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N03 ANTIEPILEPTICS
N03A ANTIEPILEPTICS
N03AA Barbiturates and derivatives
N03AA02 Phenobarbital
D00506 Phenobarbital (JP18/USP/INN) <JP>
USP drug classification [BR:br08302]
Anticonvulsants
Gamma-aminobutyric Acid (GABA) Augmenting Agents
Barbituates
Phenobarbital
D00506 Phenobarbital (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
112 Hypnotics and sedatives, anxiolytics
1125 Barbiturates and thiobarbiturates
D00506 Phenobarbital (JP18/USP/INN)
113 Antiepileptics
1134 Barbiturates
D00506 Phenobarbital (JP18/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01567 GABA-A receptor agonist
DG00845 Phenobarbital
D00506 Phenobarbital
DG03199 Antiepileptic agent
DG01904 Barbiturate antiepileptic
DG00845 Phenobarbital
D00506 Phenobarbital
Metabolizing enzyme inducer
DG01637 CYP1A2 inducer
DG00845 Phenobarbital
D00506 Phenobarbital
DG02891 CYP2B6 inducer
DG00845 Phenobarbital
D00506 Phenobarbital
DG02886 CYP2C9 inducer
DG00845 Phenobarbital
D00506 Phenobarbital
DG02853 CYP3A/CYP3A4 inducer
DG00845 Phenobarbital
D00506 Phenobarbital
Drug classes [BR:br08332]
Neuropsychiatric agent
DG03199 Antiepileptic agent
D00506 Phenobarbital
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00506 Phenobarbital (JP18/USP/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00506 Phenobarbital
D00506 Phenobarbital tablets
D00506 10% Phenobarbital powder
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00506
Prodrugs [br08324.html]
D00506
Narcotics and psychotropics in Japan [br08308.html]
Psychotropics by Control Act Article 2 Table 31 (10 substances)
D00506
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01567 GABA-A receptor agonist
DG00845 Phenobarbital
DG03199 Antiepileptic agent
DG01904 Barbiturate antiepileptic
DG00845 Phenobarbital
Metabolizing enzyme inducer
DG01637 CYP1A2 inducer
DG00845 Phenobarbital
DG02891 CYP2B6 inducer
DG00845 Phenobarbital
DG02886 CYP2C9 inducer
DG00845 Phenobarbital
DG02853 CYP3A/CYP3A4 inducer
DG00845 Phenobarbital
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 17
1 C1z C 24.5688 -19.5768
2 C8y C 25.7739 -18.8690
3 C5x C 23.3288 -18.8924
4 C5x C 24.5688 -20.9807
5 C1b C 25.7679 -20.2728
6 C8x C 26.9847 -19.5534
7 C8x C 25.7562 -17.4653
8 N1x N 22.1238 -19.5768
9 O5x O 23.3288 -17.4770
10 N1x N 23.3288 -21.6826
11 O5x O 25.7621 -21.6826
12 C1a C 27.1718 -20.2728
13 C8x C 28.1895 -18.8457
14 C8x C 26.9612 -16.7574
15 C5x C 22.1238 -20.9807
16 C8x C 28.1778 -17.4476
17 O5x O 20.9130 -21.6766
BOND 18
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 2
6 2 7 1
7 3 8 1
8 3 9 2
9 4 10 1
10 4 11 2
11 5 12 1
12 6 13 1
13 7 14 2
14 8 15 1
15 13 16 2
16 15 17 2
17 10 15 1
18 14 16 1
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