| Entry |
|
|---|
| Name |
Dichlorphenamide (USP);
Diclofenamide (JAN/INN);
Daranide (TN);
Keveyis (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C6H6Cl2N2O4S2
|
|---|
| Exact mass |
303.9146
|
|---|
| Mol weight |
305.1588
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01534 Carbonic anhydrase inhibitor
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiglaucoma, Antiepileptic, Carbonic anhydrase inhibitor |
|---|
| Disease |
|
|---|
| Comment |
Sulfonamide derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04964 | Proximal tubule bicarbonate reclamation |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
| map07055 | Sulfonamide derivatives - overview |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EC Carbonic anhydrase inhibitors
S01EC02 Diclofenamide
D00518 Dichlorphenamide (USP) <US>
USP drug classification [BR:br08302]
Genetic, Enzyme, or Protein Disorder: Replacement, Modifiers, Treatment
Dichlorphenamide
D00518 Dichlorphenamide (USP)
Drug groups [BR:br08330]
Cardiovascular agent
DG01534 Carbonic anhydrase inhibitor
D00518 Dichlorphenamide
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D00518 Dichlorphenamide
Drug classes [BR:br08332]
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D00518 Dichlorphenamide
Target-based classification of drugs [BR:br08310]
Enzymes
Lyases (EC4)
Aldehyde-lyases
CA
D00518 Dichlorphenamide (USP) <US>
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 16
1 C8y C 8.9600 -15.7500
2 C8x C 8.9600 -17.1500
3 C8y C 10.1724 -17.8500
4 C8y C 11.3849 -17.1500
5 C8y C 11.3849 -15.7500
6 C8x C 10.1724 -15.0500
7 S4a S 7.7476 -15.0500
8 S4a S 12.6160 -15.0390
9 N1a N 6.5351 -14.3500
10 O3c O 8.4630 -13.8335
11 O3c O 7.0437 -16.2469
12 N1a N 13.8284 -14.3390
13 O3c O 11.9167 -13.8281
14 O3c O 13.3168 -16.2526
15 X Cl 10.1724 -19.2498
16 X Cl 12.6160 -17.8610
BOND 16
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 5 8 1
9 7 9 1
10 7 10 2
11 7 11 2
12 8 12 1
13 8 13 2
14 8 14 2
15 3 15 1
16 4 16 1
|
|---|
