| Entry |
|
|---|
| Name |
Chlorothiazide (JAN/USP/INN);
Diuril (TN) |
|---|
| Product |
|
|---|
| Formula |
C7H6ClN3O4S2
|
|---|
| Exact mass |
294.9488
|
|---|
| Mol weight |
295.7232
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Product (DG00268): | D00519<US> D03471<US> |
|
|---|
| Efficacy |
Antihypertensive, Diuretic, Na+-Cl- symport inhibitor |
|---|
| Disease |
|
|---|
| Comment |
Thiazides
|
|---|
| Target |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
| map07055 | Sulfonamide derivatives - overview |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C03 DIURETICS
C03A LOW-CEILING DIURETICS, THIAZIDES
C03AA Thiazides, plain
C03AA04 Chlorothiazide
D00519 Chlorothiazide (JAN/USP/INN) <US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Diuretics, Thiazide
Chlorothiazide
D00519 Chlorothiazide (JAN/USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01749 Thiazide diuretic
DG00268 Chlorothiazide
D00519 Chlorothiazide
DG01690 Sulfonamide diuretic
DG01749 Thiazide diuretic
DG00268 Chlorothiazide
D00519 Chlorothiazide
Drug classes [BR:br08332]
Cardiovascular agent
DG03231 Antihypertensive
D00519 Chlorothiazide
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A3 (TSC)
D00519 Chlorothiazide (JAN/USP/INN) <US>
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01749 Thiazide diuretic
DG00268 Chlorothiazide
DG01690 Sulfonamide diuretic
DG01749 Thiazide diuretic
DG00268 Chlorothiazide
|
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| Other DBs |
|
|---|
| KCF data |
ATOM 17
1 C8y C 19.8889 -15.0612
2 C8y C 19.8946 -16.4185
3 C8x C 21.0648 -14.3768
4 S2x S 18.7070 -14.3943
5 C8x C 21.0705 -17.0914
6 N5x N 18.7304 -17.1088
7 C8y C 22.2407 -15.0495
8 N4x N 17.5371 -15.0846
9 O3c O 17.3849 -13.5811
10 O3c O 19.9298 -13.5577
11 C8y C 22.2465 -16.4068
12 C8x C 17.5488 -16.4419
13 S4a S 23.4166 -14.3651
14 X Cl 23.4283 -17.0797
15 N1a N 24.6568 -13.5168
16 O3c O 24.5457 -15.3714
17 O3c O 22.3284 -13.3295
BOND 18
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 1
8 4 9 2
9 4 10 2
10 5 11 2
11 6 12 2
12 7 13 1
13 11 14 1
14 13 15 1
15 13 16 2
16 13 17 2
17 7 11 1
18 8 12 1
|
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