| Entry |
|
|---|
| Name |
Nitrazepam (JP18/USAN/INN);
Benzalin (TN);
Nitrazepam (TN) |
|---|
| Formula |
C15H11N3O3
|
|---|
| Exact mass |
281.08
|
|---|
| Mol weight |
281.2661
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01835 Benzodiazepine sedative-hypnotics
DG03202 Hypnotic
DG01567 GABA-A receptor agonist
DG03199 Antiepileptic agent
DG02036 Benzodiazepine derivative, antiepileptic
|
|---|
| Remark |
|
|---|
| Efficacy |
Anticonvulsant, Sedative-hypnotic |
|---|
| Comment |
Benzodiazepine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N05 PSYCHOLEPTICS
N05C HYPNOTICS AND SEDATIVES
N05CD Benzodiazepine derivatives
N05CD02 Nitrazepam
D00531 Nitrazepam (JP18/USAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
112 Hypnotics and sedatives, anxiolytics
1124 Benzodiazepins
D00531 Nitrazepam (JP18/USAN/INN)
113 Antiepileptics
1139 Others
D00531 Nitrazepam (JP18/USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01835 Benzodiazepine sedative-hypnotics
D00531 Nitrazepam
DG03202 Hypnotic
D00531 Nitrazepam
DG01567 GABA-A receptor agonist
D00531 Nitrazepam
DG03199 Antiepileptic agent
DG02036 Benzodiazepine derivative, antiepileptic
D00531 Nitrazepam
Drug classes [BR:br08332]
Neuropsychiatric agent
DG03202 Hypnotic
D00531 Nitrazepam
DG03199 Antiepileptic agent
D00531 Nitrazepam
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00531 Nitrazepam (JP18/USAN/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00531 Nitrazepam
Narcotics and psychotropics in Japan [br08308.html]
Psychotropics by Control Act Article 2 Table 31 (10 substances)
D00531
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C2y C 12.1312 -8.7786
2 C8y C 11.2876 -7.6671
3 C8y C 11.6234 -6.3079
4 N1x N 12.8866 -5.7287
5 N2x N 13.5395 -8.7339
6 C5x C 14.1424 -6.3521
7 C1x C 14.4294 -7.7233
8 C8x C 10.6145 -5.3378
9 C8x C 9.2701 -5.7265
10 C8y C 8.9343 -7.0857
11 C8x C 9.9432 -8.0556
12 O5x O 15.1884 -5.4161
13 N2b N 7.5671 -7.4808 #+
14 C8y C 11.4955 -10.0306
15 C8x C 10.0915 -10.0306
16 C8x C 9.3902 -11.2452
17 C8x C 10.0915 -12.4597
18 C8x C 11.4955 -12.4597
19 C8x C 12.1968 -11.2452
20 O3a O 7.5671 -8.8833
21 O3a O 6.4666 -6.6538 #-
BOND 23
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 6 12 2
14 10 13 1
15 1 14 1
16 14 15 1
17 15 16 2
18 16 17 1
19 17 18 2
20 18 19 1
21 14 19 2
22 13 20 2
23 13 21 1
|
|---|
