| Entry |
|
|---|
| Name |
Enflurane (JP18/USP/INN);
Ethrane (TN) |
|---|
| Formula |
C3H2ClF5O
|
|---|
| Exact mass |
183.9714
|
|---|
| Mol weight |
184.4924
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG02030 Anesthetics
DG02027 General anesthetics
DG02028 Inhalational anaesthetics
DG01994 Halogenated hydrocarbons
Metabolizing enzyme substrate
DG02855 CYP2E1 substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Anesthetic (inhalation) |
|---|
| Comment |
Halogenated alkane derivative
|
|---|
| Metabolism |
Enzyme: CYP2E1 [HSA: 1571]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AB Halogenated hydrocarbons
N01AB04 Enflurane
D00543 Enflurane (JP18/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG02027 General anesthetics
DG02028 Inhalational anaesthetics
DG01994 Halogenated hydrocarbons
D00543 Enflurane
Metabolizing enzyme substrate
DG02855 CYP2E1 substrate
D00543 Enflurane
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00543 Enflurane
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00543
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 10
1 C1d C 21.2160 -16.6601
2 C1c C 20.0090 -17.3599
3 O2a O 22.4231 -17.3599
4 X F 21.2160 -15.2606
5 X F 21.2101 -18.0654
6 X F 18.7903 -16.6601
7 X Cl 20.0090 -18.7594
8 C1c C 23.6359 -16.6601
9 X F 24.8489 -17.3599
10 X F 23.6359 -15.2606
BOND 9
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 1
6 2 7 1
7 3 8 1
8 8 9 1
9 8 10 1
|
|---|
