KEGG DRUG: Etomidate

DRUG: Etomidate

Entry

D00548                      Drug

Name

Etomidate (USP/INN);
Amidate (TN)

Product

AMIDATE (Henry Schein), AMIDATE (Hospira), AMIDATE(TM) ETOMIDATE (HF Acquisition Co LLC), AMIDATE(TM) ETOMIDATE (HF Acquisition Co LLC)

Generic

ETOMIDATE (Armas Pharmaceuticals), ETOMIDATE (Caplin Steriles Limited), ETOMIDATE (Civica), ETOMIDATE (Eugia US LLC), ETOMIDATE (Fosun Pharma USA), ETOMIDATE (Fresenius Kabi USA), ETOMIDATE (Fresenius Kabi USA), ETOMIDATE (Gland Pharma Limited), ETOMIDATE (HF Acquisition Co LLC), ETOMIDATE (HF Acquisition Co LLC), ETOMIDATE (Hikma Pharmaceuticals USA), ETOMIDATE (Hikma Pharmaceuticals USA), ETOMIDATE (Mylan Institutional LLC), ETOMIDATE (Sagent Pharmaceuticals), ETOMIDATE (Zydus Lifesciences Limited), ETOMIDATE (Zydus Pharmaceuticals USA), ETOMIDATE INJECTION, SOLUTION (HF Acquisition Co LLC)

Formula

C14H16N2O2

Exact mass

244.1212

Mol weight

244.289

Structure

Simcomp

Class

Neuropsychiatric agent
DG02030 Anesthetics
DG02027 General anesthetics

Remark

Same as:

C07522

ATC code:

N01AX07

Product:

D00548<US>

Efficacy

Sedative-hypnotic

Target

GABRA1 [HSA:2554] [KO:K05175]

Pathway

hsa04080

Neuroactive ligand-receptor interaction

Interaction

Structure map

map07026

Antifungal agents

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01A ANESTHETICS, GENERAL
    N01AX Other general anesthetics
     N01AX07 Etomidate
      D00548  Etomidate (USP/INN) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
  DG02030  Anesthetics
   DG02027  General anesthetics
    D00548  Etomidate
Target-based classification of drugs [BR:br08310]
Ion channels
  Ligand-gated ion channels
   GABA (ionotropic)
    GABRA1
     D00548  Etomidate (USP/INN) <US>

Other DBs

CAS:	33125-97-2

PubChem:

7847614

ChEBI:

4910

PDB-CCD:

V8D[PDBj]

LigandBox:

D00548

NIKKAJI:

J17.549H J335.015K

KCF data

ATOM        18
            1   N4y N    18.6294  -16.3821
            2   C8y C    19.9715  -15.9761
            3   C1c C    17.3983  -15.6728
            4   C8x C    18.6071  -17.7926
            5   C8x C    20.7629  -17.1255
            6   C8y C    16.1847  -16.3821
            7   C1a C    17.3983  -14.2714
            8   N5x N    19.9334  -18.2459
            9   C8x C    14.9711  -15.6728
            10  C8x C    16.1847  -17.7775
            11  C8x C    13.8216  -16.3821
            12  C8x C    14.9711  -18.4809
            13  C8x C    13.7575  -17.7892
            14  C7a C    19.9715  -14.5732
            15  O7a O    21.1620  -13.8860
            16  O6a O    18.7483  -13.8667
            17  C1b C    22.3637  -14.5800
            18  C1a C    23.5518  -13.8941
BOND        19
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     3   7 1 #Up
            7     4   8 2
            8     6   9 2
            9     6  10 1
            10    9  11 1
            11   10  12 2
            12   11  13 2
            13    5   8 1
            14   12  13 1
            15    2  14 1
            16   14  15 1
            17   14  16 2
            18   15  17 1
            19   17  18 1

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