KEGG DRUG: Prilocaine

DRUG: Prilocaine

Entry

D00553                      Drug

Name

Prilocaine (USP/INN);
Propitocaine (JAN)

Formula

C13H20N2O

Exact mass

220.1576

Mol weight

220.3107

Structure

Simcomp

Class

Cardiovascular agent
DG01575  Calcium channel blocker
  DG01573  Calcium channel T type blocker
Neuropsychiatric agent
DG02030  Anesthetics
  DG01675  Local anesthetic
   DG01673  Amide type local anesthetic

Remark

Same as:

C07531

ATC code:

N01BB04

Chemical structure group:

DG00803

Product (DG00803):

D01243<US>

Product (mixture):

D02740<JP/US>

Efficacy

Anesthetic (local)

Target

SCN1A [HSA:6323] [KO:K04833]
SCN2A [HSA:6326] [KO:K04834]
SCN3A [HSA:6328] [KO:K04836]
SCN4A [HSA:6329] [KO:K04837]
SCN5A [HSA:6331] [KO:K04838]
SCN8A [HSA:6334] [KO:K04840]
SCN9A [HSA:6335] [KO:K04841]
SCN10A [HSA:6336] [KO:K04842]
SCN11A [HSA:11280] [KO:K04843]

Pathway

hsa04728

Dopaminergic synapse

Interaction

Structure map

map07231

Sodium channel blocking drugs

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01B ANESTHETICS, LOCAL
    N01BB Amides
     N01BB04 Prilocaine
      D00553  Prilocaine (USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
  DG01575  Calcium channel blocker
   DG01573  Calcium channel T type blocker
    DG00803  Prilocaine
     D00553  Prilocaine
Neuropsychiatric agent
  DG02030  Anesthetics
   DG01675  Local anesthetic
    DG01673  Amide type local anesthetic
     DG00803  Prilocaine
      D00553  Prilocaine
Target-based classification of drugs [BR:br08310]
Ion channels
  Voltage-gated ion channels
   Sodium channels
    SCN1A
     D00553  Prilocaine (USP/INN)
    SCN2A
     D00553  Prilocaine (USP/INN)
    SCN3A
     D00553  Prilocaine (USP/INN)
    SCN4A
     D00553  Prilocaine (USP/INN)
    SCN5A
     D00553  Prilocaine (USP/INN)
    SCN8A
     D00553  Prilocaine (USP/INN)
    SCN9A
     D00553  Prilocaine (USP/INN)
    SCN10A
     D00553  Prilocaine (USP/INN)
    SCN11A
     D00553  Prilocaine (USP/INN)
Drug groups [BR:br08330]
Cardiovascular agent
  DG01575  Calcium channel blocker
   DG01573  Calcium channel T type blocker
    DG00803  Prilocaine
Neuropsychiatric agent
  DG02030  Anesthetics
   DG01675  Local anesthetic
    DG01673  Amide type local anesthetic
     DG00803  Prilocaine

Other DBs

CAS:

721-50-6

PubChem:

ChEBI:

LigandBox:

NIKKAJI:

KCF data

ATOM        16
            1   C8y C    19.9828  -18.3051
            2   N1b N    21.2173  -19.0214
            3   C8y C    18.7484  -19.0272
            4   C8x C    19.9828  -16.8786
            5   C5a C    22.4459  -18.2935
            6   C8x C    17.5198  -18.3051
            7   C1a C    18.7601  -20.4420
            8   C8x C    18.7484  -16.1683
            9   C1c C    23.6686  -19.0214
            10  O5a O    22.5042  -17.2164
            11  C8x C    17.5198  -16.8786
            12  N1b N    24.9029  -18.2935
            13  C1a C    23.6628  -20.4130
            14  C1b C    26.1432  -19.0214
            15  C1b C    27.3601  -18.2935
            16  C1a C    28.5770  -18.9806
BOND        16
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     3   7 1
            7     4   8 2
            8     5   9 1
            9     5  10 2
            10    6  11 2
            11    9  12 1
            12    9  13 1
            13   12  14 1
            14   14  15 1
            15   15  16 1
            16    8  11 1

» Japanese version » Back

DBGET integrated database retrieval system