 | | DRUG: Pramipexole dihydrochloride | |
| Entry |
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| Name |
Pramipexole dihydrochloride (USP);
Pramipexole hydrochloride hydrate (JAN);
Pramipexole dihydrochloride monohydrate;
Mirapex (TN) |
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| Product |
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| Generic |
PRAMIPEXOLE (Camber Pharmaceuticals), PRAMIPEXOLE DIHYDROCHLORIDE (A-S Medication Solutions), PRAMIPEXOLE DIHYDROCHLORIDE (A-S Medication Solutions), PRAMIPEXOLE DIHYDROCHLORIDE (Alembic Pharmaceuticals Limited), PRAMIPEXOLE DIHYDROCHLORIDE (Alembic Pharmaceuticals Limited), PRAMIPEXOLE DIHYDROCHLORIDE (Alembic Pharmaceuticals Limited), PRAMIPEXOLE DIHYDROCHLORIDE (Alembic Pharmaceuticals), PRAMIPEXOLE DIHYDROCHLORIDE (Alembic Pharmaceuticals), PRAMIPEXOLE DIHYDROCHLORIDE (American Health Packaging), PRAMIPEXOLE DIHYDROCHLORIDE (Aurobindo Pharma Limited), PRAMIPEXOLE DIHYDROCHLORIDE (Bryant Ranch Prepack), PRAMIPEXOLE DIHYDROCHLORIDE (Bryant Ranch Prepack), PRAMIPEXOLE DIHYDROCHLORIDE (Bryant Ranch Prepack), PRAMIPEXOLE DIHYDROCHLORIDE (Bryant Ranch Prepack), PRAMIPEXOLE DIHYDROCHLORIDE (Dr. Reddy's Laboratories Limited), PRAMIPEXOLE DIHYDROCHLORIDE (Glenmark Pharmaceuticals), PRAMIPEXOLE DIHYDROCHLORIDE (Golden State Medical Supply), PRAMIPEXOLE DIHYDROCHLORIDE (Ingenus Pharmaceuticals), PRAMIPEXOLE DIHYDROCHLORIDE (Macleods Pharmaceuticals Limited), PRAMIPEXOLE DIHYDROCHLORIDE (Major Pharmaceuticals), PRAMIPEXOLE DIHYDROCHLORIDE (NorthStar RxLLC), PRAMIPEXOLE DIHYDROCHLORIDE (Rising Pharma Holdings), PRAMIPEXOLE DIHYDROCHLORIDE (ScieGen Pharmaceuticals), PRAMIPEXOLE DIHYDROCHLORIDE (Strides Pharma Science Limited), PRAMIPEXOLE DIHYDROCHLORIDE (Torrent Pharmaceuticals Limited), PRAMIPEXOLE DIHYDROCHLORIDE (Unichem Pharmaceuticals (USA)), PRAMIPEXOLE DIHYDROCHLORIDE (Vitruvias Therapeutics), PRAMIPEXOLE DIHYDROCHLORIDE (Xiamen LP Pharmaceutical), PRAMIPEXOLE DIHYDROCHLORIDE (Zydus Lifesciences Limited), PRAMIPEXOLE DIHYDROCHLORIDE (Zydus Lifesciences Limited), PRAMIPEXOLE DIHYDROCHLORIDE (Zydus Pharmaceuticals USA), PRAMIPEXOLE DIHYDROCHLORIDE (Zydus Pharmaceuticals USA) |
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| Formula |
C10H17N3S. 2HCl. H2O
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| Exact mass |
301.0782
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| Mol weight |
302.2642
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| Structure |
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| Simcomp |
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| Class |
Neuropsychiatric agent
DG01472 Dopamine agonist
DG01967 Antiparkinson agent
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| Remark |
| Product (DG00863): | D00559<JP/US> |
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| Efficacy |
Antidepressant, Antiparkinsonian, Dopamine receptor agonist |
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| Disease |
Parkinson disease [DS: H00057] Restless legs syndrome [DS: H01597] |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Structure map |
| map07213 | Dopamine receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04B DOPAMINERGIC AGENTS
N04BC Dopamine agonists
N04BC05 Pramipexole
D00559 Pramipexole dihydrochloride (USP) <JP/US>
USP drug classification [BR:br08302]
Antiparkinson Agents
Dopamine Agonists
Pramipexole
D00559 Pramipexole dihydrochloride (USP)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
116 Antiparkinsonian agents
1169 Others
D00559 Pramipexole dihydrochloride (USP); Pramipexole hydrochloride hydrate (JAN)
119 Miscellaneous
1190 Miscellaneous
D00559 Pramipexole dihydrochloride (USP); Pramipexole hydrochloride hydrate (JAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01472 Dopamine agonist
DG00863 Pramipexole
D00559 Pramipexole dihydrochloride
DG01967 Antiparkinson agent
DG00863 Pramipexole
D00559 Pramipexole dihydrochloride
Drug classes [BR:br08332]
Neuropsychiatric agent
DG01967 Antiparkinson agent
D00559 Pramipexole dihydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D00559 Pramipexole dihydrochloride (USP) <JP/US>
DRD3
D00559 Pramipexole dihydrochloride (USP) <JP/US>
DRD4
D00559 Pramipexole dihydrochloride (USP) <JP/US>
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D00559
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D00559
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01472 Dopamine agonist
DG00863 Pramipexole
DG01967 Antiparkinson agent
DG00863 Pramipexole
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| Other DBs |
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| KCF data |
ATOM 17
1 C8y C 21.1335 -18.9431
2 C8y C 21.1744 -17.5455
3 N5x N 22.5777 -19.3681
4 C1x C 20.0330 -19.6475
5 C1x C 20.0274 -16.8467
6 S2x S 22.5720 -17.1086
7 C8y C 23.3987 -18.2384
8 C1x C 18.8276 -18.9548
9 C1y C 18.8219 -17.5513
10 N1a N 24.8023 -18.2793
11 N1b N 17.6048 -16.8524
12 C1b C 16.3936 -17.5572
13 C1b C 15.1884 -16.8583
14 C1a C 13.9771 -17.5629
15 X Cl 29.1282 -17.3329
16 O0 O 29.1804 -19.7534
17 X Cl 29.1282 -17.3329
BOND 15
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 1
8 5 9 1
9 7 10 1
10 9 11 1 #Down
11 11 12 1
12 12 13 1
13 13 14 1
14 6 7 1
15 8 9 1
BRACKET 1 27.5100 -18.2000 27.5100 -16.5200
1 30.0300 -16.5200 30.0300 -18.2000
1 2
ORIGINAL 1 15
REPEAT 1 17
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