| Entry |
|
|---|
| Name |
Propylthiouracil (JP18/USP/INN);
Propylthiouracil (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C7H10N2OS
|
|---|
| Exact mass |
170.0514
|
|---|
| Mol weight |
170.2321
|
|---|
| Structure |
|
|---|
| Simcomp |
|
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| Class |
Hormonal agent
DG01934 Antithyroid agent
|
|---|
| Remark |
| Therapeutic category: | 2432 |
|
|---|
| Efficacy |
Antithyroid, Thyroid hormone synthesis inhibitor |
|---|
| Disease |
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04919 | Thyroid hormone signaling pathway |
|
|---|
| Network |
|
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| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H03 THYROID THERAPY
H03B ANTITHYROID PREPARATIONS
H03BA Thiouracils
H03BA02 Propylthiouracil
D00562 Propylthiouracil (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Hormonal Agents, Suppressant (Thyroid)
Antithyroid Agents
Propylthiouracil
D00562 Propylthiouracil (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
243 Thyroid and parathyroid hormone preparations
2432 Antithyroid hormones
D00562 Propylthiouracil (JP18/USP/INN)
Drug groups [BR:br08330]
Hormonal agent
DG01934 Antithyroid agent
D00562 Propylthiouracil
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Peroxidase
TPO
D00562 Propylthiouracil (JP18/USP/INN) <JP/US>
Thyroxine 5'-deiodinase
DIO1
D00562 Propylthiouracil (JP18/USP/INN) <JP/US>
DIO2
D00562 Propylthiouracil (JP18/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00562 Propylthiouracil
D00562 Propylthiouracil tablets
|
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| Other DBs |
|
|---|
| KCF data |
ATOM 11
1 C8y C 25.3173 -19.8324
2 C8x C 25.3173 -18.4289
3 N4x N 26.5346 -20.5256
4 C1b C 24.1060 -20.5256
5 C8y C 26.5346 -17.7243
6 C8y C 27.7461 -19.8324
7 C1b C 22.8887 -19.8324
8 N4x N 27.7461 -18.4289
9 O5x O 26.5346 -16.3265
10 S0 S 28.9574 -20.5256
11 C1a C 21.6774 -20.5313
BOND 11
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 1
7 5 8 1
8 5 9 2
9 6 10 2
10 7 11 1
11 6 8 1
|
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