 | | DRUG: Warfarin sodium | |
| Entry |
|
|---|
| Name |
Warfarin sodium (USP);
Coumadin (TN);
Jantoven (TN) |
|---|
| Product |
|
|---|
| Generic |
JANTOVEN (Upsher-Smith Laboratories), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (American Health Packaging), WARFARIN SODIUM (American Health Packaging), WARFARIN SODIUM (Amneal Pharmaceuticals LLC), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Cardinal Health 107), WARFARIN SODIUM (Cardinal Health 107), WARFARIN SODIUM (DIRECT RX), WARFARIN SODIUM (Direct_Rx), WARFARIN SODIUM (Exelan Pharmaceuticals), WARFARIN SODIUM (Golden State Medical Supply), WARFARIN SODIUM (Golden State Medical Supply), WARFARIN SODIUM (Northwind Pharmaceuticals), WARFARIN SODIUM (Northwind Pharmaceuticals), WARFARIN SODIUM (Northwind Pharmaceuticals), WARFARIN SODIUM (NuCare Pharmaceuticals), WARFARIN SODIUM (PD-Rx Pharmaceuticals), WARFARIN SODIUM (Preferred Pharmaceuticals), WARFARIN SODIUM (Preferred Pharmaceuticals), WARFARIN SODIUM (Preferred Pharmaceuticals), WARFARIN SODIUM (Preferred Pharmaceuticals), WARFARIN SODIUM (Proficient Rx LP), WARFARIN SODIUM (Proficient Rx LP), WARFARIN SODIUM (Proficient Rx LP), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (Rising Health), WARFARIN SODIUM (Taro Pharmaceuticals U.S.A.), WARFARIN SODIUM (Teva Pharmaceuticals USA), WARFARIN SODIUM (Zydus Lifesciences Limited), WARFARIN SODIUM (Zydus Pharmaceuticals USA) |
|---|
| Formula |
C19H15O4. Na
|
|---|
| Exact mass |
330.0868
|
|---|
| Mol weight |
330.3098
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Blood modifier agent
DG01950 Antithrombotic agent
DG01708 Coumarin anticoagulant
DG01760 Warfarin and analog
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
|
|---|
| Remark |
| Product (DG00149): | D00564<US> D01280<JP> |
|
|---|
| Efficacy |
Anticoagulant, Vitamin K antagonist |
|---|
| Comment |
Coumarin derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa00130 | Ubiquinone and other terpenoid-quinone biosynthesis |
|
|---|
| Metabolism |
Enzyme: CYP2C9 [HSA: 1559]
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
B01 ANTITHROMBOTIC AGENTS
B01A ANTITHROMBOTIC AGENTS
B01AA Vitamin K antagonists
B01AA03 Warfarin
D00564 Warfarin sodium (USP) <US>
USP drug classification [BR:br08302]
Blood Products and Modifiers
Anticoagulants
Vitamin K Antagonist
Warfarin
D00564 Warfarin sodium (USP)
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01708 Coumarin anticoagulant
DG01760 Warfarin and analog
DG00149 Warfarin
D00564 Warfarin sodium
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
DG00149 Warfarin
D00564 Warfarin sodium
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
NAD(P)H dehydrogenase
NQO1
D00564 Warfarin sodium (USP) <US>
Vitamin-K-epoxide reductase
VKORC1
D00564 Warfarin sodium (USP) <US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00564
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00564
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01708 Coumarin anticoagulant
DG01760 Warfarin and analog
DG00149 Warfarin
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
DG00149 Warfarin
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 24
1 C8y C 24.8370 -17.3313
2 C1c C 26.0487 -18.0418
3 C8y C 23.6253 -18.0245
4 C8y C 24.8428 -15.9389
5 C1b C 27.2662 -17.3429
6 C8y C 22.4252 -17.3137
7 O1a O 23.6894 -19.4226 #-
8 O7x O 23.6427 -15.2398
9 O6a O 26.0661 -15.2515
10 C5a C 28.4721 -18.0534
11 C8y C 22.4311 -15.9215
12 C8x C 21.2135 -18.0245
13 C1a C 28.4662 -19.4576
14 O5a O 29.6837 -17.3604
15 C8x C 21.2193 -15.2224
16 C8x C 20.0077 -17.3196
17 C8x C 20.0077 -15.9156
18 C8y C 26.0423 -19.4449
19 C8x C 24.8108 -20.1486
20 C8x C 24.8046 -21.5475
21 C8x C 26.0129 -22.2524
22 C8x C 27.2445 -21.5486
23 C8x C 27.2507 -20.1497
24 Z Na 21.3600 -19.4568 #+
BOND 25
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 3 6 1
6 3 7 1
7 4 8 1
8 4 9 2
9 5 10 1
10 6 11 2
11 6 12 1
12 10 13 1
13 10 14 2
14 11 15 1
15 12 16 2
16 15 17 2
17 8 11 1
18 16 17 1
19 2 18 1
20 18 19 2
21 19 20 1
22 20 21 2
23 21 22 1
24 22 23 2
25 18 23 1
|
|---|
|
» Japanese version » Back
|
|