Entry |
|
Name |
Sodium salicylate (JP18/USP); Salsonin (TN) |
Formula |
C7H5O3. Na
|
Exact mass |
160.0136
|
Mol weight |
160.1026
|
Structure |
|
Simcomp |
|
Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01909 Anti-inflammatory drug, salicylic acid derivatives
|
Remark |
Therapeutic category: | 1143 |
Product (mixture): | D04011<JP> D04022<JP> |
|
Efficacy |
Analgesic, Anti-inflammatory, COX inhibitor |
Comment |
Salicylic acid derivative
|
Target |
|
Pathway |
|
Interaction |
|
Structure map |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02B OTHER ANALGESICS AND ANTIPYRETICS
N02BA Salicylic acid and derivatives
N02BA04 Sodium salicylate
D00566 Sodium salicylate (JP18/USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
114 Antipyretics and analgesics, anti-inflammatory agents
1143 Salicylates
D00566 Sodium salicylate (JP18/USP)
Risk category of Japanese OTC drugs [BR:br08312]
Designated second-class OTC drugs
Inorganic and organic chemicals
Salicylic acid
D00566 Sodium salicylate (JP18/USP)
Second-class OTC drugs
Inorganic and organic chemicals
Salicylic acid
D00566 Sodium salicylate (JP18/USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01909 Anti-inflammatory drug, salicylic acid derivatives
D00566 Sodium salicylate
Drug classes [BR:br08332]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
D00566 Sodium salicylate
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D00566 Sodium salicylate (JP18/USP) <JP>
PTGS2 (COX2)
D00566 Sodium salicylate (JP18/USP) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00566 Sodium salicylate
|
Other DBs |
|
KCF data |
ATOM 11
1 C8y C 25.3293 -17.7688
2 C8y C 26.5351 -18.4678
3 C8x C 24.1118 -18.4678
4 C6a C 25.3350 -16.3708
5 C8x C 26.5351 -19.8659
6 O1a O 27.7466 -17.7688
7 C8x C 24.1118 -19.8659
8 O6a O 24.1176 -15.6602
9 O6a O 26.5408 -15.6661 #-
10 C8x C 25.3293 -20.5706
11 Z Na 28.6476 -15.7372 #+
BOND 10
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 2
8 4 9 1
9 5 10 2
10 7 10 1
|